The protective efficacy of Quercetin and Naringenin against radiation-related submandibular gland injury in female rats: A histopathological, immunohistochemical, and biochemical study

Objectifs. – Notre travail a visé à évaluer l’anxiété, la dépression et le trouble de stress post-traumatique post maladie à coronavirus 2019 (Covid-19) et à identifier les facteurs associés.

Patients et méthodes. – Nous avons mené une étude transversale durant la période allant du 1er mars 2021 au 15 mai 2021 à l’unité Covid-19 du service de pneumologie à l’hôpital Hédi Chaker Sfax (Tunisie). L’évaluation psychométrique a été réalisée à l’aide des échelles « Hospital Anxiety and Depression Scale », « Impact of Event Scale-Revised » et « Self-Reported Instrument Measuring Covid-19 Related Stigma ».

Résultats. – Notre étude a inclus 154 patients. La prévalence de l’anxiété, la dépression et le trouble de stress post traumatique étaient de 24,7 %, 11 % et 13,6 % respectivement. Nous avons constaté une association entre la dépression et le sexe féminin (p = 0,025), l’atteinte gastro-intestinale (p = 0,002) et la stigmatisation (p = 0,002). Nous avons trouvé une association entre l’anxiété et le niveau scolaire (p = 0,034), ainsi qu’entre l’anxiété et l’asthénie (p= 0,032).

Conclusions. – L’anxiété, la dépression et le trouble stress post-traumatique étaient indépendants de la majorité des caractéristiques de la maladie, notamment la sévérité de la Covid-19.

Objectives. – Our study aimed to assess anxiety, depression, and post-traumatic stress disorder in post coronavirus disease 2019 (Covid-19) and identify associated factors.

Patients and methods. – Our study is a descriptive and analytical cross-sectional study carried out during the period from March 1 to May 15th 2021 on patients who were hospitalized and discharged from the Covid-19 unit in the pneumology department at the Hedi Chaker hospital in Sfax (Tunisia). Patients who met all of the following criteria were included: aged 18 and over; having a diagnosis of Covid-19 by polymerase chain reaction (PCR) and/or by CT scan; monitored at the Covid-19 unit and who their clinical conditions did not require intensive care; survivors after 3 months of leaving the service; and having given their informed and informal consent to participate in the study.

Results. – Our study included 154 patients. The prevalence of anxiety, depression and post-traumatic stress disorder was 24.7%, 11% and 13.6% respectively. We found an association between depression and female gender (p= 0.025), gastrointestinal involvement (p= 0.002) and stigma (p= 0.002). We found an association between anxiety and grade level (p= 0.034), and between anxiety and asthenia (p= 0.032).

Conclusions. – Anxiety, depression, and post-traumatic stress disorder were independent of the majority of disease characteristics including the severity of Covid-19.

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