Prakash Kumar Sahoo Susanta Kumar Biswal Mohammad Azam

Keywords: Dipicolinic acid, Metal complexes, Antimicrobial activity

Abstract

 

ABSTRACT. A novel series of mononuclear complexes of the type, [M(L)(H2O)2] [M = Co(II) (1), Ni(II) (2), Zn(II) (3), Cd(II) (4), L = dipicolinate), has been investigated using various techniques, including elemental analyses, FT-IR, 1H- and 13C NMR spectroscopy, powder XRD and thermogravimetric analysis. The results indicate that the coordination of the dipicolinic acid to the metal ions involves two carboxylate O atoms, the pyridine N atom, and two water molecules. The pyridine-2,6-dicarboxylic acid and its studied compounds have been screened against microbial species. The findings show that the complexes have higher activity in comparison to the free pyridine-dicarboxylic acid.

 

KEY WORDS: Dipicolinic acid, Metal complexes, Antimicrobial activity

 

Bull. Chem. Soc. Ethiop. 2022, 36(3), 607-615.                                                              

DOI: https://dx.doi.org/10.4314/bcse.v36i3.10