Keywords

COVID-19,Comorbidities,Severity,hospitalization

How to Cite

Ganguli, S., Howlader, S., Dey, K., Barua, S., Islam, M. N., Aquib, T. I., Partho, P. B., Chakraborty, R. R., Barua, B., Hawlader, M. D. H., & Biswas, P. K. (2022). Association of comorbidities with the COVID-19 severity and hospitalization: A study among the recovered individuals in Bangladesh. International Journal of Health Sciences, 16(4), 30-38. Retrieved from https://ijhs.org.sa/index.php/journal/article/view/6290

Abstract

Objectives: We aimed at the identification of the association of comorbidities with the COVID-19 severity and hospitalization.
Methods: It is a retrospective cross-sectional study to investigate the variation in age, sex, dwelling, comorbidities, and medication with the COVID-19 severity and hospitalization by enrolling 1025 recovered individuals while comparing their time of recovery with or without comorbidities.
Results: COVID-19 patients mostly suffered from fever. The predominant underlying medical conditions in them were hypertension (HTN) followed by diabetes mellitus (DM). Patients with cardiovascular disease (CVD) (54.3%) and hepatic disorders (HD) (43.6%) experienced higher severity. The risk of symptomatic cases was higher in aged (odds ratio, OR = 1.04, 95% CI = 1.02–1.06) and comorbid (OR = 1.87, 95% CI = 1.34–2.60) patients. T-test confirmed the differences between the comorbid and non-comorbid patients’ recovery duration. The presence of multiple comorbidities increased the time of recovery (15–27 days) and hospitalization (20–40%). Increased symptomatic cases were found for patients having DM+HTN whereas CVD+Asthma patients were found with higher percentage of severity. Besides, DM+CKD (chronic kidney disease) was associated with higher hospitalization rate. Higher odds of severity were found for DM+CVD (OR = 4.42, 95% CI = 1.81–10.78) patients. Hospitalization risk was also increased for them (OR = 5.14, 95% CI = 2.02–13.07). Moreover, if they had HTN along with DM+CVD, they were found with even higher odds (OR = 6.82, 95% CI = 2.37–19.58) for hospitalization.
Conclusion: Our study indicates that people who are aged, females, living in urban area and have comorbid conditions are at a higher risk for developing COVID-19 severity. Clinicians and health management authorities should prioritize these high-risk groups to reduce mortality attributed to the disease.