The ISBI data that support the findings of this study are openly available in the Cancer Imaging Archive at https://doi.org/10.7937/K9/TCIA.2015.zF0vlOPv, reference number47; The MSD-P data that support the findings of this study are openly available in the MICCAI Grand Challenge at https://doi.org/10.1007/978-3-642-33418-4_51, reference number48; The ProstateX data that support the findings of this study are openly available in the Cancer Imaging Archive at https://doi.orghttps://doi.org/10.1109/ISBI.2019.8759572, reference number49; The PROMISE12 data that support the findings of this study are openly available in the MICCAI Grand Challenge at http://promise12.grand-challenge.org/Results/Overview, reference number.51