1. Laribi, S, Aouba, A, Nikolaou, M, et al. Trends in death attributed to heart failure over the past two decades in Europe. Eur J Heart Fail 2012; 14: 234–239.
Google Scholar | Crossref | Medline | ISI2. The Lancet . Heart failure: The need for improved treatment and care. Lancet 2018; 392: 451.
Google Scholar | Crossref | Medline3. Senni, M, Parrella, P, De Maria, R, et al. Predicting heart failure outcome from cardiac and comorbid conditions: The 3C-HF score. Int J Cardiol 2013; 163: 206–211.
Google Scholar | Crossref | Medline | ISI4. O’Connor, CM, Whellan, DJ, Wojdyla, D, et al. Factors related to morbidity and mortality in patients with chronic heart failure with systolic dysfunction: The HF-ACTION predictive risk score model. Circ Heart Fail 2012; 5: 63–71.
Google Scholar | Crossref | Medline5. Adlam, D, Silcocks, P, Sparrow, N. Using BNP to develop a risk score for heart failure in primary care. Eur Heart J 2005; 26: 1086–1093.
Google Scholar | Crossref | Medline6. Kirkpatrick, JN, Vannan, MA, Narula, J, et al. Echocardiography in heart failure: Applications, utility, and new horizons. J Am Coll Cardiol 2007; 50: 381–396.
Google Scholar | Crossref | Medline7. Levy, WC, Mozaffarian, D, Linker, DT, et al. The Seattle Heart Failure Model: Prediction of survival in heart failure. Circulation 2006; 113: 1424–1433.
Google Scholar | Crossref | Medline | ISI8. Aaronson, KD, Schwartz, JS, Chen, TM, et al. Development and prospective validation of a clinical index to predict survival in ambulatory patients referred for cardiac transplant evaluation. Circulation 1997; 95: 2660–2667.
Google Scholar | Crossref | Medline | ISI9. Agostoni, P, Corra, U, Cattadori, G, et al. Metabolic exercise test data combined with cardiac and kidney indexes, the MECKI score: A multiparametric approach to heart failure prognosis. Int J Cardiol 2013; 167: 2710–2718.
Google Scholar | Crossref | Medline | ISI10. O’Neill, JO, Young, JB, Pothier, CE, et al. Peak oxygen consumption as a predictor of death in patients with heart failure receiving beta-blockers. Circulation 2005; 111: 2313–2318.
Google Scholar | Crossref | Medline | ISI11. Opasich, C, Pinna, GD, Bobbio, M, et al. Peak exercise oxygen consumption in chronic heart failure: Toward efficient use in the individual patient. J Am Coll Cardiol 1998; 31: 766–775.
Google Scholar | Crossref | Medline | ISI12. Kleber, FX, Vietzke, G, Wernecke, KD, et al. Impairment of ventilatory efficiency in heart failure: Prognostic impact. Circulation 2000; 101: 2803–2809.
Google Scholar | Crossref | Medline | ISI13. Ponikowski, P, Francis, DP, Piepoli, MF, et al. Enhanced ventilatory response to exercise in patients with chronic heart failure and preserved exercise tolerance: Marker of abnormal cardiorespiratory reflex control and predictor of poor prognosis. Circulation 2001; 103: 967–972.
Google Scholar | Crossref | Medline | ISI14. Arena, R, Myers, J, Abella, J, et al. Development of a ventilatory classification system in patients with heart failure. Circulation 2007; 115: 2410–2417.
Google Scholar | Crossref | Medline | ISI15. Francis, DP, Shamim, W, Davies, LC, et al. Cardiopulmonary exercise testing for prognosis in chronic heart failure: continuous and independent prognostic value from VE/VCO(2)slope and peak VO(2). Eur Heart J 2000; 21: 154–161.
Google Scholar | Crossref | Medline | ISI16. Corra, U, Mezzani, A, Bosimini, E, et al. Ventilatory response to exercise improves risk stratification in patients with chronic heart failure and intermediate functional capacity. Am Heart J 2002; 143: 418–426.
Google Scholar | Crossref | Medline | ISI17. Stevenson, LW, Sietsema, K, Tillisch, JH, et al. Exercise capacity for survivors of cardiac transplantation or sustained medical therapy for stable heart failure. Circulation 1990; 81: 78–85.
Google Scholar | Crossref | Medline | ISI18. Mancini, DM, Eisen, H, Kussmaul, W, et al. Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure. Circulation 1991; 83: 778–786.
Google Scholar | Crossref | Medline | ISI19. Piepoli, MF, Corra, U, Agostoni, PG, et al. Statement on cardiopulmonary exercise testing in chronic heart failure due to left ventricular dysfunction: Recommendations for performance and interpretation Part II: How to perform cardiopulmonary exercise testing in chronic heart failure. Eur J Cardiovasc Prev Rehabil 2006; 13: 300–311.
Google Scholar | Medline20. Sauerbrei, W, Royston, P. Building multivariable prognostic and diagnostic models: Transformation of the predictors by using fractional polynomials. J R Stat Soc Ser A Stat Soc 1999; 162: 71–94.
Google Scholar | Crossref | ISI21. Corra, U, Agostoni, P, Giordano, A, et al. The metabolic exercise test data combined with Cardiac And Kidney Indexes (MECKI) score and prognosis in heart failure. A validation study. Int J Cardiol 2016; 203: 1067–1072.
Google Scholar | Crossref | Medline | ISI22. Freitas, P, Aguiar, C, Ferreira, A, et al. Comparative analysis of four scores to stratify patients with heart failure and reduced ejection fraction. Am J Cardiol 2017; 120: 443–449.
Google Scholar | Crossref | Medline23. Agostoni, P, Paolillo, S, Mapelli, M, et al. Multiparametric prognostic scores in chronic heart failure with reduced ejection fraction: a long-term comparison. European journal of heart failure 2018; 20: 700–710.
Google Scholar | Crossref | Medline24. Agostoni, P, Corra, U, Cattadori, G, et al. Prognostic value of indeterminable anaerobic threshold in heart failure. Circulation Heart failure 2013; 6: 977–987.
Google Scholar | Crossref | Medline | ISI25. Agostoni, P, Paolillo, S, Mapelli, M, et al. Multiparametric prognostic scores in chronic heart failure with reduced ejection fraction: a long-term comparison. European journal of heart failure 2017.
Google Scholar26. Bruno, N, Sinagra, G, Paolillo, S, et al. Mineralocorticoid receptor antagonists for heart failure: a real-life observational study. ESC heart failure 2018.
Google Scholar27. Campodonico, J, Piepoli, M, Clemenza, F, et al. Dose-dependent efficacy of beta-blocker in patients with chronic heart failure and atrial fibrillation. International journal of cardiology 2018; 273: 141–146.
Google Scholar | Crossref | Medline28. Carriere, C, Corra, U, Piepoli, M, et al. Anaerobic Threshold and Respiratory Compensation Point Identification During Cardiopulmonary Exercise Tests in Chronic Heart Failure. Chest 2019; 156: 338–347.
Google Scholar | Crossref | Medline29. Carriere, C, Corra, U, Piepoli, M, et al. Isocapnic buffering period: From physiology to clinics. European journal of preventive cardiology 2019; 26: 1107–1114.
Google Scholar | SAGE Journals | ISI30. Carubelli, V, Metra, M, Corra, U, et al. Exercise Performance Is a Prognostic Indicator in Elderly Patients With Chronic Heart Failure–Application of Metabolic Exercise Cardiac Kidney Indexes Score. Circulation journal: official journal of the Japanese Circulation Society 2015; 79: 2608–2015.
Google Scholar | Crossref | Medline31. Cattadori, G, Agostoni, P, Corra, U, et al. Severe heart failure prognosis evaluation for transplant selection in the era of beta-blockers: role of peak oxygen consumption. International journal of cardiology 2013; 168: 5078–5081.
Google Scholar | Crossref | Medline | ISI32. Cattadori, G, Agostoni, P, Corra, U, et al. Heart failure and anemia: Effects on prognostic variables. European journal of internal medicine 2017; 37: 56–63.
Google Scholar | Crossref | Medline33. Corra, U, Agostoni, P, Giordano, A, et al. Sex Profile and Risk Assessment With Cardiopulmonary Exercise Testing in Heart Failure: Propensity Score Matching for Sex Selection Bias. The Canadian journal of cardiology 2016; 32: 754–759.
Google Scholar | Crossref | Medline34. Corra, U, Agostoni, P, Piepoli, MF. Metabolic exercise data combined with cardiac and kidney indexes: MECKI score. Predictive role in cardiopulmonary exercise testing with low respiratory exchange ratio in heart failure. International journal of cardiology 2015; 184: 299–301.
Google Scholar | Crossref | Medline35. Magri, D, Agostoni, P, Corra, U, et al. Deceptive meaning of oxygen uptake measured at the anaerobic threshold in patients with systolic heart failure and atrial fibrillation. European journal of preventive cardiology 2015; 22: 1046–1055.
Google Scholar | SAGE Journals | ISI36. Paolillo, S, Agostoni, P, Masarone, D, et al. Prognostic role of atrial fibrillation in patients affected by chronic heart failure. Data from the MECKI score research group. European journal of internal medicine 2015; 26: 515–520.
Google Scholar | Crossref | Medline37. Paolillo, S, Mapelli, M, Bonomi, A, et al. Prognostic role of beta-blocker selectivity and dosage regimens in heart failure patients. Insights from the MECKI score database. European journal of heart failure 2017; 19: 904–914.
Google Scholar | Crossref | Medline38. Paolillo, S, Veglia, F, Salvioni, E, et al. Heart failure prognosis over time: how the prognostic role of oxygen consumption and ventilatory efficiency during exercise has changed in the last 20 years. European journal of heart failure 2019.
Google Scholar | Crossref39. Piepoli, MF, Corra, U, Veglia, F, et al. Exercise tolerance can explain the obesity paradox in patients with systolic heart failure: data from the MECKI Score Research Group. European journal of heart failure 2016; 18: 545–553.
Google Scholar | Crossref | Medline | ISI40. Piepoli, MF, Salvioni, E, Corra, U, et al. Increased serum uric acid level predicts poor prognosis in mildly severe chronic heart failure with reduced ejection fraction. An analysis from the MECKI score research group. European journal of internal medicine 2019.
Google Scholar | Medline41. Rovai, S, Corra, U, Piepoli, M, et al. Exercise oscillatory ventilation and prognosis in heart failure patients with reduced and mid-range ejection fraction. European journal of heart failure 2019; 21: 1586–1595.
Google Scholar | Crossref | Medline42. Salvioni, E, Corra, U, Piepoli, M, et al. Gender and age normalization and ventilation efficiency during exercise in heart failure with reduced ejection fraction. ESC heart failure 2020.
Google Scholar43. Scrutinio, D, Agostoni, P, Gesualdo, L, et al. Renal function and peak exercise oxygen consumption in chronic heart failure with reduced left ventricular ejection fraction. Circulation journal: official journal of the Japanese Circulation Society 2015; 79: 583–591.
Google Scholar | Crossref | Medline44. Arzilli, C, Aimo, A, Vergaro, G, et al. N-terminal fraction of pro-B-type natriuretic peptide versus clinical risk scores for prognostic stratification in chronic systolic heart failure. European journal of preventive cardiology 2018; 25: 889–895.
Google Scholar | SAGE Journals | ISI45. Guazzi, M. Cardiopulmonary exercise testing and risk stratification in heart failure with reduced, midrange or preserved ejection fraction: When nomenclature may not match with pathophysiology. Eur J Prev Cardiol 2018; 392–394.
Google Scholar