Assessment of Adverse Events Reported to The Poison Control and Forensic Chemistry Center in Jeddah, Saudi Arabia

Abstract (English)

Background Poisoning is a major public health threat in many countries across the globe, including Saudi Arabia. Poison control facilities help to provide immediate treatment to the patients affected by poisoning. Poisoning cases from various regions of the Kingdom are reported to the Poison Control and Forensic Chemistry Centers.

Aims This study aimed at assessment of the demographics, risk factors and management of various poisoning cases reported at the Poison Control and Forensic Chemistry Center in Jeddah, Saudi Arabia.

Methods Data was collected from the poisoning archived forms, between 01-01-2019 to 30-12-2019. A data collection sheet was designed to collect information about the region of call, age and gender of the patient, type, place, route and pattern of poisoning. All the data was analyzed through SPSS software.

Results Most cases of intoxications were occurred and reported from the Western Region of Saudi Arabia (n=97, 38%), and were for males (n=137, 54%). The majority of poisoning cases occurred in children under 5-years of age (n=198, 78%). Poisoning cases were accidental (n=233, 92%) and intentional (n=11, 4%), and most (n=246, 96%) occurred at home. Drug poisoning was more common (n=155, 61%) than chemical poisoning (n=92, 36%). The rout of poisoning was oral in the vast majority of incidents (n=242, 94%). Intentional poisoning was more common in females (n=8, 3%). All poisoning reports initiated by physicians and other healthcare professionals (n=253, 100%), within one hour of the poisoning (n=144, 57%) and after one home (n=109, 43%). Decontamination with active charcoal (n=62, 24%) was the most common method recommended to manage intoxicated patients, followed by gastric lavage (n=9, 3.5%).

Conclusion The current study assessed the reports of adverse events in a poisoning center in Saudi Arabia, most cases were related to medicines, followed by chemicals and most occurred at home. Most of poisoning cases are unintentional and occurred at home due to ingestion of medicinal products. Therefore, awareness of parents about the potent poisons at home may help to minimize the occurrence of such adverse events.

Competing Interest Statement

The authors have declared no competing interest.

Funding Statement

No funding was received.

Author Declarations

All relevant ethical guidelines have been followed; any necessary IRB and/or ethics committee approvals have been obtained and details of the IRB/oversight body are included in the manuscript.

Yes

All necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived.

Yes

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

Yes

I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.

Yes

Data Availability

Data was collected from the poisoning archived forms, between 01-01-2019 to 30-12-2019.

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