Ovarian metastases of pancreatic adenocarcinoma: clinical presentation, role of surgery, and potential value of the mutational profile for the differential diagnosis with primary mucinous ovarian carcinoma

1. Falchook, GS, Wolff, RA, Varadhachary, GR. Clinicopathologic features and treatment strategies for patients with pancreatic adenocarcinoma and ovarian metastases. Gynecol Oncol 2008; 108: 515–519.
Google Scholar | Crossref | Medline2. Moore, RG, Chung, M, Granai, CO, et al. Incidence of metastasis to the ovaries from nongenital tract primary tumors. Gynecol Oncol 2004; 93: 87–91.
Google Scholar | Crossref | Medline | ISI3. Fujiwara, K, Ohishi, Y, Koike, H, et al. Clinical implications of metastases to the ovary. Gynecol Oncol 1995; 59: 124–128.
Google Scholar | Crossref | Medline4. Mazur, MT, Hsueh, S, Gersell, DJ. Metastases to the female genital tract. Analysis of 325 cases. Cancer 1984; 53: 1978–1984.
Google Scholar | Crossref | Medline | ISI5. Ulbright, TM, Roth, LM, Stehman, FB. Secondary ovarian neoplasia. A clinicopathologic study of 35 cases. Cancer 1984; 53: 1164–1174.
Google Scholar | Crossref | Medline6. Young, RH, Hart, WR. Metastases from carcinomas of the pancreas simulating primary mucinous tumors of the ovary. A report of seven cases. Am J Surg Pathol 1989; 13: 748–756.
Google Scholar | Crossref | Medline7. Young, RH . From Krukenberg to today: the ever present problems posed by metastatic tumors in the ovary: part I. Historical perspective, general principles, Mucinous tumors including the Krukenberg tumor. Adv Anat Pathol 2006; 13: 205–227.
Google Scholar | Crossref | Medline8. Classic pages in obstetrics and gynecology: Friedrich Ernst Krukenberg Fibrosarcoma ovarii mucocellulare (carcinomatodes) . Archiv für Gynäkologie, vol 50, pp. 287–321, 1896. Am J Obstet Gynecol 1973; 117: 575.
Google Scholar | Medline9. Petru, E, Pickel, H, Heydarfadai, M, et al. Nongenital cancers metastatic to the ovary. Gynecol Oncol 1992; 44: 83–86.
Google Scholar | Crossref | Medline | ISI10. Habib, A, Khatun, S. Krukenberg tumor: report of two cases. Mymensingh Med J 2012; 21: 348–352.
Google Scholar | Medline11. Niwa, K, Yoshimi, N, Sugie, S, et al. A case of double cancer (pancreatic and ovarian adenocarcinomas) diagnosed by exfoliative and fine needle aspiration cytology. Jpn J Clin Oncol 1988; 18: 167–173.
Google Scholar | Medline12. Nomoto, D, Hashimoto, D, Motohara, T, et al. Hepatobiliary and pancreatic: rapid growing cystic ovarian metastasis from pancreatic cancer. J Gastroenterol Hepatol 2016; 31: 707.
Google Scholar | Crossref | Medline13. Hart, WR. Diagnostic challenge of secondary (metastatic) ovarian tumors simulating primary endometrioid and mucinous neoplasms. Pathol Int 2005; 55: 231–243.
Google Scholar | Crossref | Medline14. Meriden, Z, Yemelyanova, AV, Vang, R, et al. Ovarian metastases of pancreaticobiliary tract adenocarcinomas: analysis of 35 cases, with emphasis on the ability of metastases to simulate primary ovarian mucinous tumors. Am J Surg Pathol 2011; 35: 276–288.
Google Scholar | Crossref | Medline15. Yazigi, R, Sandstad, J. Ovarian involvement in extragenital cancer. Gynecol Oncol 1989; 34: 84–87.
Google Scholar | Crossref | Medline16. Lowery, M, Klimstra, D, Hedvat, C, et al. A case of synchronous pancreatic ductal adenocarcinoma and ovarian mucinous cystic neoplasm: use of Kras mutation molecular phenotyping to demonstrate independent primary origin. Gastrointest Cancer Res 2012; 5: 67–70.
Google Scholar | Medline17. Bamford, S, Dawson, E, Forbes, S, et al. The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website. Br J Cancer 2004; 91: 355–358.
Google Scholar | Crossref | Medline | ISI18. Ayhan, A, Guvenal, T, Salman, MC, et al. The role of cytoreductive surgery in nongenital cancers metastatic to the ovaries. Gynecol Oncol 2005; 98: 235–241.
Google Scholar | Crossref | Medline19. Golan, T, Hammel, P, Reni, M, et al. Maintenance olaparib for germline BRCA-mutated metastatic pancreatic cancer. N Engl J Med 2019; 381: 317–327.
Google Scholar | Crossref | Medline20. Martino, C, Pandya, D, Lee, R, et al. ATM-mutated pancreatic cancer: clinical and molecular response to gemcitabine/nab-paclitaxel after genome-based therapy resistance. Pancreas 2020; 49: 143–147.
Google Scholar | Crossref | Medline21. Goéré, D, Daveau, C, Elias, D, et al. The differential response to chemotherapy of ovarian metastases from colorectal carcinoma. Eur J Surg Oncol 2008; 34: 1335–1339.
Google Scholar | Crossref | Medline22. Brieau, B, Auzolle, C, Pozet, A, et al. Efficacy of modern chemotherapy and prognostic factors in patients with ovarian metastases from gastric cancer: a retrospective AGEO multicentre study. Dig Liver Dis 2016; 48: 441–445.
Google Scholar | Crossref | Medline23. Gunay, Y, Demiralay, E, Demirag, A. Pancreatic metastasis of high-grade papillary serous ovarian carcinoma mimicking primary pancreas cancer: a case report. Case Rep Med 2012; 2012: 943280.
Google Scholar | Crossref | Medline24. McCluggage, WG, Wilkinson, N. Metastatic neoplasms involving the ovary: a review with an emphasis on morphological and immunohistochemical features. Histopathology 2005; 47: 231–247.
Google Scholar | Crossref | Medline | ISI25. Prat, J. Ovarian carcinomas, including secondary tumors: diagnostically challenging areas. Mod Pathol 2005; 18: S99–S111.
Google Scholar | Crossref | Medline26. Baker, PM, Oliva, E. Immunohistochemistry as a tool in the differential diagnosis of ovarian tumors: an update. Int J Gynecol Pathol 2005; 24: 39–55.
Google Scholar | Medline27. Goldstein, NS, Bassi, D, Uzieblo, A. WT1 is an integral component of an antibody panel to distinguish pancreaticobiliary and some ovarian epithelial neoplasms. Am J Clin Pathol 2001; 116: 246–252.
Google Scholar | Crossref | Medline28. Vang, R, Gown, AM, Barry, TS, et al. Immunohistochemistry for estrogen and progesterone receptors in the distinction of primary and metastatic mucinous tumors in the ovary: an analysis of 124 cases. Mod Pathol 2006; 19: 97–105.
Google Scholar | Crossref | Medline | ISI29. Lee, KR, Young, RH. The distinction between primary and metastatic mucinous carcinomas of the ovary: gross and histologic findings in 50 cases. Am J Surg Pathol 2003; 27: 281–292.
Google Scholar | Crossref | Medline | ISI30. Auner, V, Kriegshäuser, G, Tong, D, et al. KRAS mutation analysis in ovarian samples using a high sensitivity biochip assay. BMC Cancer 2009; 9: 111.
Google Scholar | Crossref | Medline31. Iacobuzio-Donahue, CA, Fu, B, Yachida, S, et al. DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer. J Clin Oncol 2009; 27: 1806–1813.
Google Scholar | Crossref | Medline | ISI32. Grünewald, K, Lyons, J, Fröhlich, A, et al. High frequency of Ki-ras codon 12 mutations in pancreatic adenocarcinomas. Int J Cancer 1989; 43: 1037–1041.
Google Scholar | Crossref | Medline | ISI33. Bournet, B, Muscari, F, Buscail, C, et al. KRAS G12D mutation subtype is a prognostic factor for advanced pancreatic adenocarcinoma. Clin Transl Gastroenterol 2016; 7: e157.
Google Scholar | Crossref | Medline

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