Background

In implant prosthodontics, computer-assisted design and computer-assisted manufacturing (CAD/CAM) zirconia abutments bonded onto titanium bases are frequently used in prosthetic dentistry. Unpolymerized monomer of the bonding material or the adhesive gap itself may have a negative effect on peri-implant tissue health. However, evidence addressing this problem is not available.

Purpose

The aim of the current trial was to study inflammatory effects of individualized abutments bonded onto titanium bases.

Material and Method

A total of 24 patients with one test abutment and one control abutment each participated in this prospective, double-blind, randomized controlled clinical trial. Thereby, test abutments were CAD/CAM titanium abutments bonded onto titanium abutments (Ti-Base). As control abutments individualized, one-piece CAD/CAM titanium abutments were used. At abutment installation as well as 6 and 12 months thereafter bone level changes, clinical parameters as well as Il-1β levels were assessed.

Results

Neither for bone level or clinical parameters nor for Il-1β levels, significant differences between test and control abutments could be found. However, in both groups Il-1β levels were significantly elevated at both the 6 and 12 months follow-up compared to baseline.

Conclusion

Within the limits of this RCT, it can be concluded that effects on the inflammatory state of peri-implant tissues do not differ between individualized abutments bonded onto Ti-Bases and individualized one-piece abutments.