O Abdel-Rahman: advisory boards and honorarium from Roche Canada and Eisai Canada. C Wu: advisory boards and honorarium from LEO Pharma, Pfizer, BMS-Pfizer and Servier; local principal investigator for clinical trials with support from BMS-Pfizer, Daiichi-Sankyo, and Bayer. J Easaw: speaking honoraria from Amgen, LEO Pharma. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.