The possible effects of iron loss from bloodletting on mortality from pneumonia in the nineteenth century

Patients with phlebotomyEnrico Acerbi (1785-1827)1Pre-1820Milan, Maggiore HospitalAll

All indicates both uncomplicated and complicated cases

1421611.1René Laennec (1781-1826)2Pre-1826ParisAll--12.0 -16.0William Pulteney Alison (1790-1859)3Post-1822Edinburgh Royal InfirmaryAll8225.0Jean-Baptiste Bouillard (1796 -1881)41831-1834Paris, Hôpital de la CharitéAll1021211.8Gabriel Andral (1797-1876)5Pre- 1834Paris, Hôpital de la CharitéUncomplicated291448.3Complicated362261.1Pierre-Charles-Louis (1787-1872)61828-1835Paris, Hôpital de la Charité
Paris, Hôpital de la PitiéAll
All76
2927
435.5
13.8James Jackson (1777-1867)71825-1834Massachusetts General HospitalAll33412.1John Hughes Bennett (1812-1875)81812-1837Edinburgh Royal InfirmaryAll501938.0Pierre Briquet (1796 -1881)91836-1839Paris, Hôpital CochinAll1402920.7Jόzef Dietl (1804-1878)10Pre-1840

Uncertain period of enrolment, probably before 1840

Vienna, Wieden HospitalMostly large bleedings.
7 uncomplicated cases851722.0John Hughes Bennett111839-1849Edinburgh Royal InfirmaryAll64822234.3Magnus von Huss (1807-1890)121840-1847Stockholm, Seraphim-Lazarethe HospitalAlso with local bleedings. Two-thirds uncomplicated104012011.5Robert Bentley Todd (1809 -1860)131840-1847London, King's College Hospital-25416.0Hermann Lebert (1813-1878)141853-1859Zurich Hospital4 cases complicated205157.3All investigators264852719.9Patients without phlebotomyJohn Rasori (1767-1823)15Pre-1823Milan, Santa Corona Hospital-64814322.1M. Grisolle (1811-1869)16Pre- 1841

Uncertain period of enrolment, probably before 1840

Paris, L'Hôtel-DieuUncomplicated 1st stage

Stages following presentation: first is initial 24 hours; second is 2nd - 3rd days; third is 4th - 6th days


Uncomplicated 2n

Stages following presentation: first is initial 24 hours; second is 2nd - 3rd days; third is 4th - 6th days

stage50
1825
3210.0
17.6Jόzef Dietl17Pre-1840

Uncertain period of enrolment, probably before 1840

Vienna, Wieden HospitalDeaths all complicated2953612.2John Hughes Bennett181849-1863Edinburgh Royal InfirmaryAll11532.6Karl Kissel191852

Date of publication, not date of patient recruitment.

Germany, location not specifiedIron acetate orally if
alkaline urine11254.5Magnus von Huss201848-1855Stockholm, Seraphim Lazarethe HospitalTwo thirds uncomplicated cases157616110.2Karl Heinrich.Thielmann (1802-1872)21Pre-1852

Uncertain period of enrolment, probably before 1840

St Petersburg, Peter and Paul's Hospital,57 1st stage (no deaths)
32 2n

Stages following presentation: first is initial 24 hours; second is 2nd - 3rd days; third is 4th - 6th days

stage (3 deaths)
24 3r

Stages following presentation: first is initial 24 hours; second is 2nd - 3rd days; third is 4th - 6th days

stage (8 deaths)113119.7F.J.J.Schmidt221851-1854Rotterdam Krankenhuis-37410.8Heinrich von Bamburger (1822-1888)231857

Uncertain period of enrolment, probably before 1840

Wurzburg, Julius HospitalFew leeches applied in minority1862111.3Professor Dr Rigler241856-1858Gratz, General HospitalVenesection in only 4 cases; leeches in several1192016.8Robert Bentley Todd
251847-1859London, King's College Hospital-53611.3All investigators348644712.8

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