Qin X, Zi H, Zeng X. Changes in the global burden of untreated dental caries from 1990 to 2019: a systematic analysis for the Global Burden of Disease study. Heliyon. 2022;8(9):e10714.

Article  PubMed  PubMed Central  Google Scholar 

Shoaee S, Ghasemi E, Sofi-Mahmudi A, Shamsoddin E, Tovani-Palone MR, Roshani S, Heydari MH, Yoosefi M, Masinaei M, Azadnaejafabadi S, et al. Global, regional, and national burden and quality of care index (QCI) of oral disorders: a systematic analysis of the global burden of disease study 1990–2017. BMC Oral Health. 2024;24(1):116.

Article  PubMed  PubMed Central  Google Scholar 

Carvalho JC. Caries process on occlusal surfaces: evolving evidence and understanding. Caries Res. 2014;48(4):339–46.

Article  CAS  PubMed  Google Scholar 

Akinlotan M, Chen B, Fontanilla TM, Chen A, Fan VY. Economic evaluation of dental sealants: a systematic literature review. Community Dent Oral Epidemiol. 2018;46(1):38–46.

Article  PubMed  Google Scholar 

Quinonez RB, Downs SM, Shugars D, Christensen J, Vann WF Jr. Assessing cost-effectiveness of sealant placement in children. J Public Health Dent. 2005;65(2):82–9.

Article  PubMed  Google Scholar 

Liu W, Xiong L, Li J, Guo C, Fan W, Huang S. The anticaries effects of pit and fissure sealant in the first permanent molars of school-age children from Guangzhou: a population-based cohort study. BMC Oral Health. 2019;19(1):156.

Article  PubMed  PubMed Central  Google Scholar 

Papacchini F, Cury AH, Goracci C, Chieffi N, Tay FR, Polimeni A, Ferrari M. Noninvasive pit and fissure sealing: microtensile bond strength to intact bovine enamel of different pit and fissure sealants in a simplified fissure model. J Adhes Dent. 2006;8(6):375–80.

CAS  PubMed  Google Scholar 

Kasemkhun P, Nakornchai S, Phonghanyudh A, Srimaneekarn N. The efficacy of dental sealant used with bonding agent on occlusal caries (ICDAS 2–4): a 24-month randomized clinical trial. Int J Paediatr Dent. 2021;31(6):760–6.

Article  PubMed  Google Scholar 

Memarpour M, Baghdagabadi NA, Bardideh E. Shear Bond Strength and Microleakage of Fissure Sealant to Contaminated and Non-contaminated Enamel: a systematic review and Meta-analysis of in Vitro studies. Pediatr Dent. 2023;45(5):E30–47.

Google Scholar 

Naidoo S, Potgieter C. How effective are resin-based sealants in preventing caries when placed under field conditions? S Afr dent j. 2017;72(1):22–7.

Google Scholar 

Beresescu L, Kovacs M, Vlasa A, Stoica AM, Benedek C, Pop M, Bungardean D, Esian D. Retention ability of a Glass Carbomer pit and fissure sealant. Int J Environ Res Public Health. 2022;19(4):1966.

Article  PubMed  PubMed Central  Google Scholar 

Yang SY, Choi JW, Kim KM, Kwon JS. Prevention of secondary Caries using Resin-based pit and fissure sealants containing hydrated Calcium Silicate. Polym (Basel) 2020, 12(5).

Ibrahim MS, Balhaddad AA, Garcia IM, Collares FM, Weir MD, Xu HHK, Melo MAS. pH-responsive calcium and phosphate-ion releasing antibacterial sealants on carious enamel lesions in vitro. J Dent. 2020;97:103323.

Article  CAS  PubMed  Google Scholar 

Bohns FR, Leitune VCB, Balbinot GS, Samuel SMW, Collares FM. Mineral deposition promoted by resin-based sealants with different calcium phosphate additions. Braz Oral Res. 2019;33:e101.

Article  PubMed  Google Scholar 

Jafarnia S, Valanezhad A, Abe S, Shahabi S, Watanabe I. Resin-based sealant containing sol–gel derived bioactive glass: ion release and biological response. J Solgel Sci Technol. 2021;107(1):96–104.

Article  Google Scholar 

Lee MJ, Kim JY, Seo JY, Mangal U, Cha JY, Kwon JS, Choi SH. Resin-based sealant with Bioactive Glass and Zwitterionic Material for Remineralisation and Multi-species Biofilm Inhibition. Nanomaterials (Basel). 2020;10(8):1581.

Article  CAS  PubMed  Google Scholar 

Panpisut P, Liaqat S, Zacharaki E, Xia W, Petridis H, Young AM. Dental composites with calcium / strontium phosphates and Polylysine. PLoS ONE. 2016;11(10):e0164653.

Article  PubMed  PubMed Central  Google Scholar 

Aljabo A, Abou Neel EA, Knowles JC, Young AM. Development of dental composites with reactive fillers that promote precipitation of antibacterial-hydroxyapatite layers. Mater Sci Eng C Mater Biol Appl. 2016;60:285–92.

Article  CAS  PubMed  Google Scholar 

Panpisut P, Suppapatpong T, Rattanapan A, Wongwarawut P. Monomer conversion, biaxial flexural strength, apatite forming ability of experimental dual-cured and self-adhesive dental composites containing calcium phosphate and nisin. Dent Mater J 2021, 40(2):399–406.

Alkhouri N, Xia W, Ashley PF, Young AM. Renewal MI Dental Composite Etch and Seal properties. Mater (Basel). 2022;15(15):5438.

Article  CAS  Google Scholar 

Yun J, Burrow MF, Matinlinna JP, Wang Y, Tsoi JKH. A narrative review of Bioactive Glass-Loaded Dental Resin composites. J Funct Biomater. 2022;13(4):208.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Panpisut P, Tornsatitkul P, Phadungcharoen S, Phusanti S, THE CURRENT STRATEGIES FOR ENHANCING ANTICARIES PROPERTIES OF DENTAL ADHESIVE. A REVIEW. Suranaree J Sci Technol. 2022;29(2):1–9.

Google Scholar 

Dai LL, Mei ML, Chu CH, Lo ECM. Mechanisms of Bioactive Glass on Caries Management: a review. Mater (Basel). 2019;12(24):4183.

Article  CAS  Google Scholar 

Dai LL, Mei ML, Chu CH, Lo ECM. Remineralizing effect of a new strontium-doped bioactive glass and fluoride on demineralized enamel and dentine. J Dent. 2021;108:103633.

Article  CAS  PubMed  Google Scholar 

Khvostenko D, Hilton TJ, Ferracane JL, Mitchell JC, Kruzic JJ. Bioactive glass fillers reduce bacterial penetration into marginal gaps for composite restorations. Dent Mater. 2016;32(1):73–81.

Article  CAS  PubMed  Google Scholar 

Yu F, Yu H, Lin P, Dong Y, Zhang L, Sun X, Liu Z, Guo H, Huang L, Chen J. Effect of an Antibacterial Monomer on the antibacterial activity of a pit-and-fissure sealant. PLoS ONE. 2016;11(9):e0162281.

Article  PubMed  PubMed Central  Google Scholar 

Zhu J, Chu W, Luo J, Yang J, He L, Li J. Dental materials for oral microbiota dysbiosis: an update. Front Cell Infect Microbiol. 2022;12:900918.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang Y, Wang L, Hu Y, Qin J, Yu B. Design and optimization of epsilon-poly-l-lysine with specific functions for diverse applications. Int J Biol Macromol. 2024;262(Pt 1):129513.

Article  CAS  PubMed  Google Scholar 

Hyldgaard M, Mygind T, Vad BS, Stenvang M, Otzen DE, Meyer RL. The antimicrobial mechanism of action of epsilon-poly-l-lysine. Appl Environ Microbiol. 2014;80(24):7758–70.

Article  PubMed  PubMed Central  Google Scholar 

Lygidakis NN, Allan E, Xia W, Ashley PF, Young AM. Early Polylysine Release from Dental composites and its effects on Planktonic Streptococcus mutans growth. J Funct Biomater. 2020;11(3):53.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yaghmoor RB, Abdel-Hadi M, Petridis H, Allan E, Young AM. Effects of Novel Dental composites on Streptococcus mutans Biofilms. J Funct Biomater. 2023;15(1):13.

Article  PubMed  PubMed Central  Google Scholar 

Hiraki J, Ichikawa T, Ninomiya S, Seki H, Uohama K, Seki H, Kimura S, Yanagimoto Y, Barnett JW Jr. Use of ADME studies to confirm the safety of epsilon-polylysine as a preservative in food. Regul Toxicol Pharmacol. 2003;37(2):328–40.

Article  CAS  PubMed  Google Scholar 

Hickel R, Brushaver K, Ilie N. Repair of restorations–criteria for decision making and clinical recommendations. Dent Mater. 2013;29(1):28–50.

Article  PubMed  Google Scholar 

Kanzow P, Krois J, Wiegand A, Schwendicke F. Long-term treatment costs and cost-effectiveness of restoration repair versus replacement. Dent Mater. 2021;37(6):e375–81.

Article  PubMed  Google Scholar 

Blum IR, Ozcan M. Reparative Dentistry: possibilities and limitations. Curr Oral Health Rep. 2018;5(4):264–9.

Article