Effect of Fecal Microbiota Transplant on Antibiotic Resistance Genes Among Patients with Chronic Pouchitis

Samuel S, Ingle SB, Dhillon S et al. Cumulative Incidence and Risk Factors for Hospitalization and Surgery in a Population-based Cohort of Ulcerative Colitis. Inflamm Bowel Dis 2013;19:1858–1866. https://doi.org/10.1097/MIB.0b013e31828c84c5.

Article  PubMed  Google Scholar 

Lightner AL, Mathis KL, Dozois EJ et al. Results at Up to 30 Years After Ileal Pouch-Anal Anastomosis for Chronic Ulcerative Colitis. Inflamm Bowel Dis 2017;23:781–790. https://doi.org/10.1097/MIB.0000000000001061.

Article  PubMed  Google Scholar 

Santiago P, Barnes EL, Raffals LE. Classification and Management of Disorders of the J Pouch. Am J Gastroenterol. Published online May 12, 2022:https://doi.org/10.14309/ajg.0000000000002348

Barnes EL, Herfarth HH, Kappelman MD et al. Incidence, Risk Factors, and Outcomes of Pouchitis and Pouch-Related Complications in Patients With Ulcerative Colitis. Clin Gastroenterol Hepatol 2021;19:1583. https://doi.org/10.1016/j.cgh.2020.06.035.

Article  PubMed  Google Scholar 

Bar N, Avraham Y, Dubinsky V et al. Long-term Antibiotic Treatment in Pouchitis—Patterns of Use and Safety. Inflamm Bowel Dis 2022;28:1027–1033. https://doi.org/10.1093/ibd/izab209.

Article  PubMed  Google Scholar 

Dubinsky V, Reshef L, Bar N et al. Predominantly Antibiotic-resistant Intestinal Microbiome Persists in Patients With Pouchitis Who Respond to Antibiotic Therapy. Gastroenterology 2020;158:610-624.e13. https://doi.org/10.1053/j.gastro.2019.10.001.

Article  CAS  PubMed  Google Scholar 

Landy J, Walker AW, Li JV et al. Variable alterations of the microbiota, without metabolic or immunological change, following faecal microbiota transplantation in patients with chronic pouchitis. Sci Rep 2015;5:12955. https://doi.org/10.1038/srep12955.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stallmach A, Lange K, Buening J, Sina C, Vital M, Pieper DH. Fecal Microbiota Transfer in Patients With Chronic Antibiotic-Refractory Pouchitis. Am J Gastroenterol 2016;111:441–443. https://doi.org/10.1038/ajg.2015.436.

Article  PubMed  Google Scholar 

Herfarth H, Barnes EL, Long MD et al. Combined Endoscopic and Oral Fecal Microbiota Transplantation in Patients with Antibiotic-Dependent Pouchitis: Low Clinical Efficacy due to Low Donor Microbial Engraftment. Inflamm Intest Dis 2019;4:1–6. https://doi.org/10.1159/000497042.

Article  PubMed  PubMed Central  Google Scholar 

Selvig D, Piceno Y, Terdiman J et al. Fecal Microbiota Transplantation in Pouchitis: Clinical, Endoscopic, Histologic, and Microbiota Results from a Pilot Study. Dig Dis Sci 2020;65:1099–1106. https://doi.org/10.1007/s10620-019-05715-2.

Article  CAS  PubMed  Google Scholar 

Kayal M, Lambin T, Pinotti R, Dubinsky MC, Grinspan A. A Systematic Review of Fecal Microbiota Transplant for the Management of Pouchitis. Crohns Colitis 2020;2:otaa034. https://doi.org/10.1093/crocol/otaa034.

Article  Google Scholar 

Woodworth MH, Hayden MK, Young VB, Kwon JH. The Role of Fecal Microbiota Transplantation in Reducing Intestinal Colonization With Antibiotic-Resistant Organisms: The Current Landscape and Future Directions. Open Forum Infect Dis 2019;6:ofz288. https://doi.org/10.1093/ofid/ofz288.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Steed DB, Wang T, Raheja D et al. Gram-Negative Taxa and Antimicrobial Susceptibility after Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection. mSphere 2020;5:e00853-20. https://doi.org/10.1128/mSphere.00853-20.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Millan B, Park H, Hotte N et al. Fecal Microbial Transplants Reduce Antibiotic-resistant Genes in Patients With Recurrent Clostridium difficile Infection. Clin Infect Dis Off Publ Infect Dis Soc Am 2016;62:1479–1486. https://doi.org/10.1093/cid/ciw185.

Article  CAS  Google Scholar 

Saha S, Tariq R, Tosh PK, Pardi DS, Khanna S. Faecal microbiota transplantation for eradicating carriage of multidrug-resistant organisms: a systematic review. Clin Microbiol Infect Off Publ Eur Soc Clin Microbiol Infect Dis 2019;25:958–963. https://doi.org/10.1016/j.cmi.2019.04.006.

Article  CAS  Google Scholar 

Yoon YK, Suh JW, Kang EJ, Kim JY. Efficacy and safety of fecal microbiota transplantation for decolonization of intestinal multidrug-resistant microorganism carriage: beyond Clostridioides difficile infection. Ann Med 2019;51:379–389. https://doi.org/10.1080/07853890.2019.1662477.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Merrick B, Sergaki C, Edwards L et al. Modulation of the Gut Microbiota to Control Antimicrobial Resistance (AMR)—A Narrative Review with a Focus on Faecal Microbiota Transplantation (FMT). Infect Dis Rep 2023;15:238–254. https://doi.org/10.3390/idr15030025.

Article  PubMed  PubMed Central  Google Scholar 

Nguyen GC, Leung W, Weizman AV. Increased risk of vancomycin-resistant enterococcus (VRE) infection among patients hospitalized for inflammatory bowel disease in the United States. Inflamm Bowel Dis 2011;17:1338–1342. https://doi.org/10.1002/ibd.21519.

Article  PubMed  Google Scholar 

Nguyen GC, Patel H, Chong RY. Increased prevalence of and associated mortality with methicillin-resistant Staphylococcus aureus among hospitalized IBD patients. Am J Gastroenterol 2010;105:371–377. https://doi.org/10.1038/ajg.2009.581.

Article  PubMed  Google Scholar 

McLaughlin SD, Clark SK, Roberts CH et al. Extended spectrum beta-lactamase-producing bacteria and Clostridium difficile in patients with pouchitis. Aliment Pharmacol Ther 2010;32:664–669. https://doi.org/10.1111/j.1365-2036.2010.04401.x.

Article  CAS  PubMed  Google Scholar 

Dogan B, Scherl E, Bosworth B et al. Multidrug resistance is common in Escherichia coli associated with ileal Crohn’s disease. Inflamm Bowel Dis 2013;19:141–150. https://doi.org/10.1002/ibd.22971.

Article  PubMed  Google Scholar 

Dogan B, Fu J, Zhang S, Scherl EJ, Simpson KW. Rifaximin decreases virulence of Crohn’s disease-associated Escherichia coli and epithelial inflammatory responses. J Antibiot (Tokyo) 2018;71:485–494. https://doi.org/10.1038/s41429-017-0022-y.

Article  CAS  PubMed  Google Scholar 

Sommer MOA, Dantas G, Church GM. Functional characterization of the antibiotic resistance reservoir in the human microflora. Science 2009;325:1128–1131. https://doi.org/10.1126/science.1176950.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Choi J, Thänert R, Reske KA et al. Gut Microbiome Correlates of Recurrent Urinary Tract Infection: a Longitudinal, Multi-Center Study. eClinicalMedicine. 2024. https://doi.org/10.1016/j.eclinm.2024.102490.

Article  PubMed  PubMed Central  Google Scholar 

Quan J, Langelier C, Kuchta A et al. FLASH: A Next-Generation CRISPR Diagnostic for Multiplexed Detection of Antimicrobial Resistance Sequences. Nucleic Acids Res 2019;47:e83. https://doi.org/10.1093/nar/gkz418.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zankari E, Hasman H, Cosentino S et al. Identification of Acquired Antimicrobial Resistance Genes. J Antimicrob Chemother 2012;67:2640–2644. https://doi.org/10.1093/jac/dks261.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alcock BP, Raphenya AR, Lau TTY et al. CARD 2020: Antibiotic Resistome Surveillance with the Comprehensive Antibiotic Resistance Database. Nucleic Acids Res 2020;48:D517–D525. https://doi.org/10.1093/nar/gkz935.

Article  CAS  PubMed  Google Scholar 

Love MI, Huber W, Anders S. Moderated Estimation Of Fold Change and Dispersion for RNA-seq Data with DESeq2. Genome Biol 2014;15:550. https://doi.org/10.1186/s13059-014-0550-8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

McMurdie PJ, Holmes S. phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data. PloS ONE 2013;8:e61217. https://doi.org/10.1371/journal.pone.0061217.

Article  CAS 

留言 (0)

沒有登入
gif