Medam S, Zieleskiewicz L, Duclos G, Baumstarck K, Loundou A, Alingrin J, Hammad E, Vigne C, Antonini F, Leone M (2017) Risk factors for death in septic shock: a retrospective cohort study comparing trauma and non-trauma patients. Medicine (Baltimore) 96:e9241. https://doi.org/10.1097/md.0000000000009241
Madushani R, Patel V, Loftus T, Ren Y, Li HJ, Velez L, Wu Q, Adhikari L, Efron P, Segal M, Ozrazgat-Baslanti T, Rashidi P, Bihorac A, Sepsis, Critical Illness Research Center I (2022) Early biomarker signatures in surgical sepsis. J Surg Res 277:372–383. https://doi.org/10.1016/j.jss.2022.04.052
Article CAS PubMed PubMed Central Google Scholar
Papin G, Bailly S, Dupuis C, Ruckly S, Gainnier M, Argaud L, Azoulay E, Adrie C, Souweine B, Goldgran-Toledano D, Marcotte G, Gros A, Reignier J, Mourvillier B, Forel JM, Sonneville R, Dumenil AS, Darmon M, Garrouste-Orgeas M, Schwebel C, Timsit JF, group Os (2021) Clinical and biological clusters of sepsis patients using hierarchical clustering. PLoS ONE 16:e0252793. https://doi.org/10.1371/journal.pone.0252793
Article CAS PubMed PubMed Central Google Scholar
Scicluna BP, van Vught LA, Zwinderman AH, Wiewel MA, Davenport EE, Burnham KL, Nurnberg P, Schultz MJ, Horn J, Cremer OL, Bonten MJ, Hinds CJ, Wong HR, Knight JC, van der Poll T, consortium M (2017) Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study. Lancet Respir Med 5:816–826. https://doi.org/10.1016/S2213-2600(17)30294-1
Papathanakos G, Andrianopoulos I, Xenikakis M, Papathanasiou A, Koulenti D, Blot S, Koulouras V (2023) Clinical sepsis phenotypes in critically Ill patients. Microorganisms. https://doi.org/10.3390/microorganisms11092165
Article PubMed PubMed Central Google Scholar
Lal A, Trivedi V, Rizvi MS, Amsbaugh A, Myers MK, Saleh K, Kashyap R, Gajic O (2021) Oral midodrine administration during the first 24 hours of sepsis to reduce the need of vasoactive agents: placebo-controlled feasibility clinical trial. Crit Care Explor 3:e0382. https://doi.org/10.1097/cce.0000000000000382
Article PubMed PubMed Central Google Scholar
Kalimouttou A, Lerner I, Cheurfa C, Jannot AS, Pirracchio R (2023) Machine-learning-derived sepsis bundle of care. Intensive Care Med 49:26–36. https://doi.org/10.1007/s00134-022-06928-2
Article CAS PubMed Google Scholar
Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C, Machado FR, McIntyre L, Ostermann M, Prescott HC, Schorr C, Simpson S, Wiersinga WJ, Alshamsi F, Angus DC, Arabi Y, Azevedo L, Beale R, Beilman G, Belley-Cote E, Burry L, Cecconi M, Centofanti J, Coz Yataco A, De Waele J, Dellinger RP, Doi K, Du B, Estenssoro E, Ferrer R, Gomersall C, Hodgson C, Hylander Moller M, Iwashyna T, Jacob S, Kleinpell R, Klompas M, Koh Y, Kumar A, Kwizera A, Lobo S, Masur H, McGloughlin S, Mehta S, Mehta Y, Mer M, Nunnally M, Oczkowski S, Osborn T, Papathanassoglou E, Perner A, Puskarich M, Roberts J, Schweickert W, Seckel M, Sevransky J, Sprung CL, Welte T, Zimmerman J, Levy M (2021) Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med 49:1063–1143. https://doi.org/10.1097/CCM.0000000000005337
Plata-Menchaca EP, Ruiz-Rodríguez JC, Ferrer R (2021) Evidence for the application of sepsis bundles in 2021. Semin Respir Crit Care Med 42:706–716. https://doi.org/10.1055/s-0041-1733899
Andrews B, Semler MW, Muchemwa L, Kelly P, Lakhi S, Heimburger DC, Mabula C, Bwalya M, Bernard GR (2017) Effect of an early resuscitation protocol on in-hospital mortality among adults with sepsis and hypotension: a randomized clinical trial. JAMA 318:1233–1240. https://doi.org/10.1001/jama.2017.10913
Article PubMed PubMed Central Google Scholar
Baghdadi JD, Wong MD, Uslan DZ, Bell D, Cunningham WE, Needleman J, Kerbel R, Brook R (2020) Adherence to the SEP-1 sepsis bundle in hospital-onset v. community-onset sepsis: a multicenter retrospective cohort study. J Gen Intern Med 35:1153–1160. https://doi.org/10.1007/s11606-020-05653-0
Article PubMed PubMed Central Google Scholar
Rhee C, Jones TM, Hamad Y, Pande A, Varon J, O’Brien C, Anderson DJ, Warren DK, Dantes RB, Epstein L, Klompas M, Control ftCfD, Program PPE (2019) Prevalence, underlying causes, and preventability of sepsis-associated mortality in US acute care hospitals. JAMA Netw Open 2:e187571–e187571. https://doi.org/10.1001/jamanetworkopen.2018.7571
Article PubMed PubMed Central Google Scholar
Townsend SR, Phillips GS, Duseja R, Tefera L, Cruikshank D, Dickerson R, Nguyen HB, Schorr CA, Levy MM, Dellinger RP, Conway WA, Browner WS, Rivers EP (2022) Effects of compliance with the early management bundle (SEP-1) on mortality changes among medicare beneficiaries with sepsis: a propensity score matched cohort study. Chest 161:392–406. https://doi.org/10.1016/j.chest.2021.07.2167
Pruinelli L, Westra BL, Yadav P, Hoff A, Steinbach M, Kumar V, Delaney CW, Simon G (2018) Delay within the 3-hour surviving sepsis campaign guideline on mortality for patients with severe sepsis and septic shock. Crit Care Med 46:500–505. https://doi.org/10.1097/CCM.0000000000002949
Article PubMed PubMed Central Google Scholar
August BA, Griebe KM, Stine JJ, Hauser CD, Hunsaker T, Jones MC, Martz C, Peters MA, To L, Belanger R, Schlacht S, Swiderek J, Davis SL, Mlynarek ME, Smith ZR (2022) Evaluating the impact of severe sepsis 3-hour bundle compliance on 28-day in-hospital mortality: a propensity adjusted, nested case-control study. Pharmacotherapy 42:651–658. https://doi.org/10.1002/phar.2715
Article CAS PubMed Google Scholar
Lal A, Rayes H, O’Horo JC, Singh TD, Gajic O, Kashyap R (2023) Septic shock definitions and associated outcomes in blood culture positive critically ill patients. Ann Transl Med 11:192. https://doi.org/10.21037/atm-22-5147
Article PubMed PubMed Central Google Scholar
Chen JT, Roberts RJ, Sevransky JE, Gong MN (2023) Resuscitation in the first 3 hours of sepsis-induced hypotension varies by patient and hospital factors. Crit Care Explor 5:e0859. https://doi.org/10.1097/cce.0000000000000859
Article PubMed PubMed Central Google Scholar
Boussina A, Wardi G, Shashikumar SP, Malhotra A, Zheng K, Nemati S (2023) Representation learning and spectral clustering for the development and external validation of dynamic sepsis phenotypes: observational cohort study. J Med Internet Res 25:e45614. https://doi.org/10.2196/45614
Article PubMed PubMed Central Google Scholar
Bruse N, Kooistra EJ, Jansen A, van Amstel RBE, de Keizer NF, Kennedy JN, Seymour C, van Vught LA, Pickkers P, Kox M (2022) Clinical sepsis phenotypes in critically ill COVID-19 patients. Crit Care 26:244. https://doi.org/10.1186/s13054-022-04118-6
Article PubMed PubMed Central Google Scholar
Guo F, Zhu X, Wu Z, Zhu L, Wu J, Zhang F (2022) Clinical applications of machine learning in the survival prediction and classification of sepsis: coagulation and heparin usage matter. J Transl Med 20:265. https://doi.org/10.1186/s12967-022-03469-6
Article CAS PubMed PubMed Central Google Scholar
Hussain H, Vutipongsatorn K, Jimenez B, Antcliffe DB (2022) Patient stratification in sepsis: using metabolomics to detect clinical phenotypes, sub-phenotypes and therapeutic response. Metabolites. https://doi.org/10.3390/metabo12050376
Article PubMed PubMed Central Google Scholar
Knox DB, Lanspa MJ, Kuttler KG, Brewer SC, Brown SM (2015) Phenotypic clusters within sepsis-associated multiple organ dysfunction syndrome. Intensive Care Med 41:814–822. https://doi.org/10.1007/s00134-015-3764-7
Article PubMed PubMed Central Google Scholar
Kudo D, Goto T, Uchimido R, Hayakawa M, Yamakawa K, Abe T, Shiraishi A, Kushimoto S (2021) Coagulation phenotypes in sepsis and effects of recombinant human thrombomodulin: an analysis of three multicentre observational studies. Crit Care 25:114. https://doi.org/10.1186/s13054-021-03541-5
Article PubMed PubMed Central Google Scholar
Seymour CW, Kennedy JN, Wang S, Chang CH, Elliott CF, Xu Z, Berry S, Clermont G, Cooper G, Gomez H, Huang DT, Kellum JA, Mi Q, Opal SM, Talisa V, van der Poll T, Visweswaran S, Vodovotz Y, Weiss JC, Yealy DM, Yende S, Angus DC (2019) Derivation, validation, and potential treatment implications of novel clinical phenotypes for sepsis. JAMA 321:2003–2017. https://doi.org/10.1001/jama.2019.5791
Article CAS PubMed PubMed Central Google Scholar
Tarrant C, O’Donnell B, Martin G, Bion J, Hunter A, Rooney KD (2016) A complex endeavour: an ethnographic study of the implementation of the sepsis six clinical care bundle. Implement Sci 11:149. https://doi.org/10.1186/s13012-016-0518-z
留言 (0)