Objectives: Health system resources are limited, and decision makers often need to make trade-offs between equity and efficiency. Such trade-offs are guided by public values that are elicited using choice experiments. There is no standard approach to elicit equity-efficiency trade-offs. Previous studies have found significant variability in public values, raising concerns about the robustness of trade-off experiments. The objective of this systematic review was to determine whether and how equity-efficiency trade-off studies consider validity, reliability and framing effects. Methods: We searched Medline, EMBASE, and Web of Science in January 2024 for health-related equity-efficiency trade-off studies. Two reviewers independently screened titles and abstracts, followed by full-text review, data extraction, and quality assessment. Results: 115 equity-efficiency trade-off studies were identified, of which 29 studies (25.2%) investigated validity, reliability, and/or framing effects. 14 (12.2%) studies assessed validity, 9 (7.8%) studies assessed reliability, and 10 (8.7%) assessed framing or cognitive effects. Validity was most frequently assessed by comparing results to hypothesized expectations, while reliability was commonly assessed by providing a repeated test or questionnaire. Framing and cognitive effects were assessed by varying question order or changing the wording or framing of the scenario. 19 of 23 studies reported high or acceptable validity or reliability, and 5 of 10 studies found no significant framing or cognitive effects. Conclusion: This systematic review highlights the need to consider robustness of elicited values in choice experiments. It will also guide future choice experiments that aim to estimate inequity aversion.
Competing Interest StatementThe authors have declared no competing interest.
Funding StatementThis study did not receive any funding.
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I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).
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Data AvailabilityAll data produced in the present study are available upon reasonable request to the authors.
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