Investigating the Prevalence and Risk Determinants of Ovarian Cancer in Women from Bauchi State North-East, Nigeria

Abstract

Ovarian cancer posed a significant health challenge, particularly in low-resource settings where late diagnosis and limited healthcare access contribute to high mortality rates. This cross-sectional study assessed the prevalence and risk factors for ovarian cancer among women attending General Hospital Azare, North-eastern Nigeria. Data were collected from women of reproductive age 18 and above through structured questionnaires and medical records. The study found an ovarian cancer prevalence of 7.2%, with key risk factors including family history of cancer (17.5%), early menarche, and nulliparity (66%). Despite access to healthcare, only 11.3% of participants had undergone ovarian cancer screening, and 58.8% lacked adequate knowledge of its risk factors. Urban residence (80.4%) and student status (71.1%) were linked to better healthcare access, but a significant gap in awareness persisted. Family history had the strongest association with ovarian cancer (Chi-square = 24.621, p < 0.001), although a counterintuitive negative coefficient suggested the need for further investigation. Alcohol consumption (Chi-square = 27.086, p < 0.001) and hormonal contraceptive use (Chi-square = 12.855, p = 0.0016) were also significantly associated with increased risk. Smoking (Chi-square = 8.57, p = 0.0034) further elevated the risk, while physical activity indicated no significant association. These findings highlighted the need for public health interventions, including education, awareness programs, and improved access to diagnostic services. Efforts to promote early detection and address healthcare disparities are crucial in reducing ovarian cancer risks in this population.

Competing Interest Statement

The authors have declared no competing interest.

Funding Statement

This study did not receive any funding

Author Declarations

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Yes

The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

Sa'adu Zungur University Bauchi, Faculty of Basic Medical Sciences, Research and Ethics Committee FBMSREC

I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.

Yes

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

Yes

I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.

Yes

Data Availability

All data produced in the present study are available upon reasonable request to the authors

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