Gavin Perkins. Out-of-Hospital Cardiac Arrest Overview: English Ambulance Services 2022. In: Out-of-Hospital Cardiac Arrest Outcomes, Warwick Clinical Trials Unit. 2022. https://warwick.ac.uk/fac/sci/med/research/ctu/trials/ohcao/ Accessed 1 Mar 2024.

Yan S, Gan Y, Jiang N, Wang R, Chen Y, Luo Z, et al. The global survival rate among adult out-of-hospital cardiac arrest patients who received cardiopulmonary resuscitation: a systematic review and meta-analysis. Crit Care. 2020;24(1):1–13.

Article  Google Scholar 

Scottish Ambulance Service. Scotland’s Out-of-Hospital Cardiac Arrest Report 2019–22. In: Out Of Hospital Cardiac Arrest Annual Report, Scottish Ambulance. 2022. https://www.scottishambulance.com/publications/out-of-hospital-cardiac-arrest-annual-report/ Accessed 1 Mar 2024.

NHS England. Ambulance Quality Indicators Data 2023–24 (AmbCO-Sep-23) Cardiac arrest-survival. In: Ambulance Quality Indicators, NHS England. 2024. https://www.england.nhs.uk/statistics/statistical-work-areas/ambulance-quality-indicators/ Accessed 26 Feb 2024

Nolan J, Soar J, Eikeland H. The chain of survival. Resuscitation. 2006;71(3):270–1.

Article  PubMed  Google Scholar 

Resuscitation to Recovery. A National Framework to improve care of people with out-of-hospital cardiac arrest (OHCA) in England. In: Publication: Resuscitation to Recovery, Resuscitation Council UK. 2017. Available from: https://www.resus.org.uk/library/publications/publication-resuscitation-recovery Accessed 1 Mar 2024

Song J, Guo W, Lu X, Kang X, Song Y, Gong D. The effect of bystander cardiopulmonary resuscitation on the survival of out-of-hospital cardiac arrests: a systematic review and meta-analysis. Scand J Trauma Resusc Emerg Med. 2018;26(1):1–10.

Article  Google Scholar 

Lindner TW, Søreide E, Nilsen OB, Torunn MW, Lossius HM. Good outcome in every fourth resuscitation attempt is achievable–an Utstein template report from the Stavanger region. Resuscitation. 2011;82(12):1508–13.

Article  PubMed  Google Scholar 

Sasson C, Rogers MAM, Dahl J, Kellermann AL. Predictors of survival from out-of-hospital cardiac arrest a systematic review and meta-analysis. Circ Cardiovasc Qual Outcomes. 2010;3(1):63–81.

Article  PubMed  Google Scholar 

Deakin CD. The chain of survival: not all links are equal. Resuscitation. 2018;126:80–2.

Article  PubMed  Google Scholar 

Conrad S, Rycus P. Extracorporeal membrane oxygenation for refractory cardiac arrest. Ann Card Anaesth. 2017;20(Suppl 1):S4.

Article  PubMed  PubMed Central  Google Scholar 

Maekawa K, Tanno K, Hase M, Mori K, Asai Y. Extracorporeal cardiopulmonary resuscitation for patients with out-of-hospital cardiac arrest of cardiac origin: a propensity-matched study and predictor analysis. Crit Care Med. 2013;41(5):1186–96.

Article  PubMed  Google Scholar 

Lee SW, Hong YS. Extracorporeal life-support in patients requiring CPR. Lancet. 2008;372(9638):512–4.

Article  PubMed  Google Scholar 

Richardson ASC, Tonna JE, Nanjayya V, Nixon P, Abrams DC, Raman L, et al. Extracorporeal cardiopulmonary resuscitation in adults. Interim guideline consensus statement from the extracorporeal life support organization. ASAIO J. 2021;67(3):221–8.

Article  PubMed  Google Scholar 

Bartos JA, Grunau B, Carlson C, Duval S, Ripeckyj A, Kalra R, et al. Improved survival with extracorporeal cardiopulmonary resuscitation despite progressive metabolic derangement associated with prolonged resuscitation. Circulation. 2020;141(11):877–86.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Singer B, Reynolds JC, Davies GE, Wrigley F, Whitbread M, Faulkner M, et al. Sub30: Protocol for the Sub30 feasibility study of a pre-hospital Extracorporeal membrane oxygenation (ECMO) capable advanced resuscitation team at achieving blood flow within 30 min in patients with refractory out-of-hospital cardiac arrest. Resusc Plus. 2020; 4.

Yannopoulos D, Bartos JA, Raveendran G, Conterato M, Frascone RJ, Trembley A, et al. Coronary artery disease in patients with out-of-hospital refractory ventricular fibrillation cardiac arrest. J Am Coll Cardiol. 2017;70(9):1109–17.

Article  PubMed  Google Scholar 

Stub D, Bernard S, Pellegrino V, Smith K, Walker T, Sheldrake J, et al. Refractory cardiac arrest treated with mechanical CPR, hypothermia, ECMO and early reperfusion (the CHEER trial). Resuscitation. 2015;86:88–94.

Article  PubMed  Google Scholar 

Yannopoulos D, Bartos J, Raveendran G, Walser E, Connett J, Murray TA, et al. Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial. The Lancet. 2020;396(10265):1807–16.

Article  Google Scholar 

Suverein MM, Delnoij TSR, Lorusso R, Brandon-Bravo-Bruinsma GJ, Otterspoor L, Elzo Kraemer CV, et al. Early extracorporeal CPR for refractory out-of-hospital cardiac arrest. New Engl J Med. 2023;388(4):299–309.

Article  PubMed  Google Scholar 

Belohlavek J, Smalcova J, Rob D, Franek O, Smid O, Pokorna M, et al. Effect of intra-arrest transport, extracorporeal cardiopulmonary resuscitation, and immediate invasive assessment and treatment on functional neurologic outcome in refractory out-of-hospital cardiac arrest: a randomized clinical trial. JAMA. 2022;327(8):737–47.

Article  PubMed  PubMed Central  Google Scholar 

Koen ’T Joncke, Nathanaël T, Philippe D. A systematic review of current ECPR protocols. A step towards standardisation. Resusc Plus. 2020; 3.

Training for HALO procedures. Part 1: Background and psychomotor skills. St Emlyn’s https://www.stemlynsblog.org/training-for-halo-procedures-part-1-background-and-psychomotor-skills-st-emlyns/ Accessed 25 Mar 2024

Tonna JE, Selzman CH, Mallin MP, Smith BR, Youngquist ST, Koliopoulou A, et al. Development and implementation of a comprehensive, multidisciplinary emergency department extracorporeal membrane oxygenation program. Ann Emerg Med. 2017;70(1):32–40.

Article  PubMed  Google Scholar 

Laussen PC, Guerguerian AM. Establishing and sustaining an ECPR program. Front Pediatr. 2018;6:152.

Article  PubMed  PubMed Central  Google Scholar 

Cardiac Arrest: It takes a system to save a life|Coda Change—Clinical Conferences and Podcasts https://codachange.org/cardiac-arrest-it-takes-a-system-to-save-a-life Accessed 5 Mar 2024

Panchal AR, Berg KM, Cabanãs JG, Kurz MC, Link MS, Del Rios M, et al. American heart association focused update on systems of care: dispatcher-assisted cardiopulmonary resuscitation and cardiac arrest centers: an update to the American heart association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2019;140(24):E895-903.

Article  PubMed  Google Scholar 

Høybye M, Stankovic N, Holmberg M, Christensen HC, Granfeldt A, Andersen LW. In-hospital vs out-of-hospital cardiac arrest: patient characteristics and survival. Resuscitation. 2021;158:157–65.

Article  PubMed  Google Scholar 

Kagawa E, Inoue I, Kawagoe T, Ishihara M, Shimatani Y, Kurisu S, et al. Assessment of outcomes and differences between in- and out-of-hospital cardiac arrest patients treated with cardiopulmonary resuscitation using extracorporeal life support. Resuscitation. 2010;81(8):968–73.

Article  PubMed  Google Scholar 

Kim SJ, Jung JS, Park JH, Park JS, Hong YS, Lee SW. An optimal transition time to extracorporeal cardiopulmonary resuscitation for predicting good neurological outcome in patients with out-of-hospital cardiac arrest: a propensity-matched study. Crit Care. 2014;18(5):1–15.

Article  Google Scholar 

Belohlavek J, Yannopoulos D, Smalcova J, Rob D, Bartos J, Huptych M, et al. Intraarrest transport, extracorporeal cardiopulmonary resuscitation, and early invasive management in refractory out-of-hospital cardiac arrest: an individual patient data pooled analysis of two randomised trials. EClinicalMedicine. 2023; 59.

Wengenmayer T, Rombach S, Ramshorn F, Biever P, Bode C, Duerschmied D, et al. Influence of low-flow time on survival after extracorporeal cardiopulmonary resuscitation (eCPR). Crit Care. 2017;21(1):1–6.

Article  Google Scholar 

Tran A, Rochwerg B, Fan E, Belohlavek J, Suverein MM, van de Poll MCG, et al. Prognostic factors associated with favourable functional outcome among adult patients requiring extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: a systematic review and meta-analysis. Resuscitation. 2023;193: 110004.

Article  PubMed  Google Scholar 

Park SJ, Lee SW, Han KS, Lee EJ, Jang DH, Lee SJ, et al. Optimal cardiopulmonary resuscitation duration for favorable neurological outcomes after out-of-hospital cardiac arrest. Scand J Trauma Resusc Emerg Med. 2022; 30(1).

Scquizzato T, Bonaccorso A, Swol J, Gamberini L, Scandroglio AM, Landoni G, et al. Refractory out-of-hospital cardiac arrest and extracorporeal cardiopulmonary resuscitation: a meta-analysis of randomized trials. Artif Organs. 2023;47(5):806–16.

Article  PubMed  Google Scholar 

Assouline B, Mentha N, Wozniak H, Donner V, Looyens C, Suppan L, et al. Improved extracorporeal cardiopulmonary resuscitation (ECPR) outcomes is associated with a restrictive patient selection algorithm. J Clin Med. 2024; 13(2).

Lunz D, Calabrò L, Belliato M, Contri E, Broman LM, Scandroglio AM, et al. Extracorporeal membrane oxygenation for refractory cardiac arrest: a retrospective multicenter study. Intensive Care Med. 2020;46(5):973–82.

Article  CAS  PubMed  Google Scholar 

Grunau B, Carrier S, Bashir J, Dick W, Harris L, Boone R, et al. A comprehensive regional clinical and educational ECPR protocol decreases time to ECMO in patients with refractory out-of-hospital cardiac arrest. CJEM. 2017;19(6):424–33.

Article  PubMed  Google Scholar 

ter Avest E, Tunnicliff M, Griggs J, Griffiths D, Cody D, Nelson M, et al. In-hospital extracorporeal cardiopulmonary resuscitation for patients with an out-of-hospital cardiac arrest in a semi-rural setting: an observational study on the implementation of a helicopter emergency medical services pathway. Resusc Plus. 2022; 12.

Jones D, Daglish FM, Tanner BM, Wilkie FJM. A review of pre-hospital extracorporeal cardiopulmonary resuscitation and its potential application in the North East of England. Int J Emerg Med. 2024;17(1):1–9.

Article  Google Scholar 

Tonna JE, Keenan HT, Weir C. A qualitative analysis of physician decision making in the use of extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest. Resusc Plus. 2022;11: 100278.

Article  PubMed  PubMed Central  Google Scholar 

Chonde M, Escajeda J, Elmer J, Callaway CW, Guyette FX, Boujoukos A, et al. Challenges in the development and implementation of a healthcare system based extracorporeal cardiopulmonary resuscitation (ECPR) program for the treatment of out of hospital cardiac arrest. Resuscitation. 2020;148:259–65.

Article