Say L, Chou D, Gemmill A, Tunçalp Ö, Moller AB, Daniels J, et al. Global causes of maternal death: a WHO systematic analysis. Lancet Glob Health. 2014;2(6):e323–33.

Article  PubMed  Google Scholar 

Hasegawa J, Ikeda T, Sekizawa A, Tanaka H, Nakamura M, Katsuragi S, et al. Recommendations for saving mothers’ lives in Japan: report from the Maternal Death Exploratory Committee (2010–2014). J Obstet Gynaecol Res. 2016;42(12):1637–43.

Article  PubMed  Google Scholar 

Muñoz M, Stensballe J, Ducloy-Bouthors AS, Bonnet MP, De Robertis E, Fornet I, et al. Patient blood management in obstetrics: prevention and treatment of postpartum haemorrhage. A NATA consensus statement. Blood Transfus. 2019;17(2):112–36.

PubMed  PubMed Central  Google Scholar 

Charbit B, Mandelbrot L, Samain E, Baron G, Haddaoui B, Keita H, et al. The decrease of fibrinogen is an early predictor of the severity of postpartum hemorrhage. J Thromb Haemost. 2007;5(2):266–73.

Article  CAS  PubMed  Google Scholar 

Collins PW, Lilley G, Bruynseels D, Laurent DB, Cannings-John R, Precious E, et al. Fibrin-based clot formation as an early and rapid biomarker for progression of postpartum hemorrhage: a prospective study. Blood. 2014;124(11):1727–36.

Article  CAS  PubMed  Google Scholar 

Collins PW, Cannings-John R, Bruynseels D, Mallaiah S, Dick J, Elton C, et al. Viscoelastometric-guided early fibrinogen concentrate replacement during postpartum haemorrhage: OBS2, a double-blind randomized controlled trial. Br J Anaesth. 2017;119(3):411–21.

Article  CAS  PubMed  Google Scholar 

de Lloyd L, Bovington R, Kaye A, Collis RE, Rayment R, Sanders J, et al. Standard haemostatic tests following major obstetric haemorrhage. Int J Obstet Anesth. 2011;20(2):135–41.

Article  PubMed  Google Scholar 

Park S, Sohn C, Kwon H, Kim S, Ryoo S, Ahn S, et al. Association between initial fibrinogen levels and the need for massive transfusion in emergency department patients with primary postpartum hemorrhage: a retrospective study from a single center in Korea. J Pers Med. 2024;14(4):344.

Article  PubMed  PubMed Central  Google Scholar 

Toulon P, Ozier Y, Ankri A, Fléron MH, Leroux G, Samama CM. Point-of-care versus central laboratory coagulation testing during haemorrhagic surgery. A multicenter study. Thromb Haemost. 2009;101(2):394–401.

Article  CAS  PubMed  Google Scholar 

Reikvam H, Steien E, Hauge B, Liseth K, Hagen KG, Størkson R, et al. Thrombelastography. Transfus Apher Sci. 2009;40(2):119–23.

Article  PubMed  Google Scholar 

Mohamed M, Majeske K, Sachwani GR, Kennedy K, Salib M, McCann M. The impact of early thromboelastography directed therapy in trauma resuscitation. Scand J Trauma Resusc Emerg Med. 2017;25(1):99.

Article  PubMed  PubMed Central  Google Scholar 

Trautman CL, Palmer WC, Taner CB, Canabal JM, Getz T, Goldman A, et al. Thromboelastography as a predictor of outcomes following liver transplantation. Transplant Proc. 2017;49(9):2110–6.

Article  CAS  PubMed  Google Scholar 

Welsby IJ, Jiao K, Ortel TL, Brudney CS, Roche AM, Bennett-Guerrero E, et al. The kaolin-activated Thrombelastograph predicts bleeding after cardiac surgery. J Cardiothorac Vasc Anesth. 2006;20(4):531–5.

Article  PubMed  Google Scholar 

Collins P, Abdul-Kadir R, Thachil J. Management of coagulopathy associated with postpartum hemorrhage: guidance from the SSC of the ISTH. J Thromb Haemost. 2016;14(1):205–10.

Article  CAS  PubMed  Google Scholar 

Collins PW, Bell SF, de Lloyd L, Collis RE. Management of postpartum haemorrhage: from research into practice, a narrative review of the literature and the Cardiff experience. Int J Obstet Anesth. 2019;37:106–17.

Article  CAS  PubMed  Google Scholar 

Bell SF, Collis RE, Collins PW. Comparison of haematological indices and transfusion management in severe and massive postpartum haemorrhage: analysis of a two-year national prospective observational study. Int J Obstet Anesth. 2022;50:103547.

Article  CAS  PubMed  Google Scholar 

Bell SF, Collis RE, Bailey C, James K, John M, Kelly K, et al. The incidence, aetiology, and coagulation management of massive postpartum haemorrhage: a two-year national prospective cohort study. Int J Obstet Anesth. 2021;47:102983.

Article  CAS  PubMed  Google Scholar 

Sohn CH, Kim YJ, Seo DW, Won HS, Shim JY, Lim KS, et al. Blood lactate concentration and shock index associated with massive transfusion in emergency department patients with primary postpartum haemorrhage. Br J Anaesth. 2018;121(2):378–83.

Article  CAS  PubMed  Google Scholar 

Cortet M, Deneux-Tharaux C, Dupont C, Colin C, Rudigoz RC, Bouvier-Colle MH, et al. Association between fibrinogen level and severity of postpartum haemorrhage: secondary analysis of a prospective trial. Br J Anaesth. 2012;108(6):984–9.

Article  CAS  PubMed  Google Scholar 

Collis RE, Collins PW. Haemostatic management of obstetric haemorrhage. Anaesthesia. 2015;70(Suppl 1):78–86, e27-8.

Article  PubMed  Google Scholar 

Wikkelsø AJ, Edwards HM, Afshari A, Stensballe J, Langhoff-Roos J, Albrechtsen C, et al. Pre-emptive treatment with fibrinogen concentrate for postpartum haemorrhage: randomized controlled trial. Br J Anaesth. 2015;114(4):623–33.

Article  PubMed  Google Scholar 

Gillissen A, van den Akker T, Caram-Deelder C, Henriquez D, Bloemenkamp KWM, de Maat MPM, et al. Coagulation parameters during the course of severe postpartum hemorrhage: a nationwide retrospective cohort study. Blood Adv. 2018;2(19):2433–42.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hofer S, Blaha J, Collins PW, Ducloy-Bouthors AS, Guasch E, Labate F, et al. Haemostatic support in postpartum haemorrhage: a review of the literature and expert opinion. Eur J Anaesthesiol. 2023;40(1):29–38.

PubMed  Google Scholar 

Jones RM, de Lloyd L, Kealaher EJ, Lilley GJ, Precious E, Burckett St Laurent D, et al. Platelet count and transfusion requirements during moderate or severe postpartum haemorrhage. Anaesthesia. 2016;71(6):648–56.

Article  CAS  PubMed  Google Scholar 

Huissoud C, Carrabin N, Audibert F, Levrat A, Massignon D, Berland M, et al. Bedside assessment of fibrinogen level in postpartum haemorrhage by thrombelastometry. BJOG. 2009;116(8):1097–102.

Article  CAS  PubMed  Google Scholar 

Gillissen A, van den Akker T, Caram-Deelder C, Henriquez D, Bloemenkamp KWM, Eikenboom J, et al. Comparison of thromboelastometry by ROTEM(®) Delta and ROTEM(®) sigma in women with postpartum haemorrhage. Scand J Clin Lab Investig. 2019;79(1–2):32–8.

Article  Google Scholar 

Bell SF, Roberts TCD, Freyer Martins Pereira J, De Lloyd L, Amir Z, James D, et al. The sensitivity and specificity of rotational thromboelastometry (ROTEM) to detect coagulopathy during moderate and severe postpartum haemorrhage: a prospective observational study. Int J Obstet Anesth. 2022;49:103238.

Article  CAS  PubMed  Google Scholar 

Roberts TCD, De Lloyd L, Bell SF, Cohen L, James D, Ridgway A, et al. Utility of viscoelastography with TEG 6s to direct management of haemostasis during obstetric haemorrhage: a prospective observational study. Int J Obstet Anesth. 2021;47:103192.

Article  CAS  PubMed  Google Scholar 

McNamara H, Kenyon C, Smith R, Mallaiah S, Barclay P. Four years’ experience of a ROTEM(®)-guided algorithm for treatment of coagulopathy in obstetric haemorrhage. Anaesthesia. 2019;74(8):984–91.

Article  CAS  PubMed  Google Scholar 

Sohn CH, Kim WY, Kim SR, Seo DW, Ryoo SM, Lee YS, et al. An increase in initial shock index is associated with the requirement for massive transfusion in emergency department patients with primary postpartum hemorrhage. Shock. 2013;40(2):101–5.

Article  PubMed  Google Scholar 

Escobar MF, Nassar AH, Theron G, Barnea ER, Nicholson W, Ramasauskaite D, et al. FIGO recommendations on the management of postpartum hemorrhage 2022. Int J Gynaecol Obstet. 2022;157(Suppl 1):3–50.

Article  PubMed