Int J Sports Med
DOI: 10.1055/a-2318-1880
Gengxin Dong
1
School of Sports Medicine and Rehabilitation, Beijing Sport University,
Beijing, China
,
Jianxin Wu
2
Ministry of Sports, Tsinghua University, Beijing, China
,
Yinglu Hong
1
School of Sports Medicine and Rehabilitation, Beijing Sport University,
Beijing, China
,
3
Sports Coaching College, Beijing Sport University, Beijing,
China
,
Meng Liu
3
Sports Coaching College, Beijing Sport University, Beijing,
China
,
Guole Jiang
3
Sports Coaching College, Beijing Sport University, Beijing,
China
,
Dapeng Bao
4
China Institute of Sport and Health Science, Beijing Sport University,
Beijing, China
,
Brad Manor
5
Hebrew Senior Life Hinda and Arthur Marcus Institute for Aging
Research, Harvard Medical School, Boston, United States
,
Junhong Zhou
5
Hebrew Senior Life Hinda and Arthur Marcus Institute for Aging
Research, Harvard Medical School, Boston, United States
› Author Affiliations
Funding Information
National Key Research and Development Projects of the Ministry of Science and
Technology — 2018YFC2000602
major project of Beijing Social Science Foundation: “Theory and Practice Research on
Deep Integration of National Fitness and National Health in the New Era” —
20ZDA19
› Further Information
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Abstract
Hydrogen, as an antioxidant, may have the potential to mitigate fatigue and
improve selected oxidative stress markers induced by strenuous exercise. This
study focused on a previously unexplored approach involving pre-exercise
inhalation of hydrogen-rich gas (HRG). Twenty-four healthy adult men first
completed pre-laboratories to determine maximum cycling power (Wmax)
and maximum cycling time (Tmax). Then they were subjected to ride
Tmax at 80% Wmax and 60–70 rpm on cycle ergometers
after inhaled HRG or placebo gas (air) for 60-minute in a double-blind,
counterbalanced, randomized, and crossover design. The cycling frequency in the
fatigue modeling process and the rating of perceived exertion (RPE) at the
beginning and end of the ride were recorded. Before gas inhalation and after
fatigue modeling, visual analog scale (VAS) for fatigue and counter-movement
jump (CMJ) were tested, and blood samples were obtained. The results showed that
compared to a placebo, HRG inhalation induced significant improvement in VAS,
RPE, the cycling frequency during the last 30 seconds in the fatigue modeling
process, the ability to inhibit hydroxyl radicals, and serum lactate after
exercise (p<0.028), but not in CMJ height and glutathione peroxidase
activity. The cycling frequency during the last 30 seconds of all other segments
in the fatigue modeling process was within the range of 60–70 rpm. In
conclusion, HRG inhalation prior to acute exercise can alleviate
exercise-induced fatigue, maintain functional performance, and improve hydroxyl
radical and lactate levels.
Keywords
oxidative stress -
anti-fatigue -
hydroxyl radicals -
lactate -
recovery
Publication History
Received: 04 March 2024
Accepted: 29 April 2024
Accepted Manuscript online:
02 May 2024
Article published online:
10 September 2024
© 2024. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
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