Abstract: Objectives: This study aims to assess the health-related quality of life (HRQoL) and psychiatric comorbidities among medical students suffering from migraines at the University of Khartoum. Materials and Methods: A descriptive observational cross-sectional study was conducted with 78 medical students diagnosed with migraines. Participants completed a self-reported questionnaire that included the SF-12 Health Survey to assess HRQoL and the Hopkins Symptom Checklist (HSCL-25) to evaluate psychiatric symptoms. Results: A total of 42.3% of students reported poor quality of life, particularly in the mental component (MCS) compared to the physical component (PCS). Psychiatric symptoms, including anxiety and depression, were prevalent in 70.5% of the participants. Gender was the only sociodemographic factor significantly affecting both HRQoL and psychiatric comorbidity, with females reporting poorer physical health and higher rates of psychiatric symptoms than males, consistent with findings from other studies. Conclusion: The mental aspect of quality of life is significantly impaired in medical students suffering from migraines. Psychiatric comorbidities, particularly depression and anxiety, are common in this population. Universities should maintain records of students diagnosed with migraines and implement support programs, including follow-up for medical treatment and psychiatric evaluation. Keywords: migraine, psychiatric comorbidity, quality of life, medical students, mental health

The authors have declared no competing interest.

This study did not receive any funding

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Ethics committee of the University of Khartoum, Faculty of Medicine, Department of Community Medicine gave ethical approval for this work

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