Hydroxyethyl starch (HES) is similar to glycogen as it is derived from amylopectin. It consists of ethylated polysaccharides and glucose polymers that are metabolised into smaller residues, including glucose, resulting in the potential to induce or potentiate hyperglycaemia. It was hypothesised that Voluven® 6% (130/0.4) – a third generation saline-based product with a lower molecular weight, molar substitution, and a C2/C6 ratio greater than eight compared to previous first and second generation HES – could be more easily hydrolysed by α-amylase and release glucose residues at a more rapid rate.
Author Biography KN van Rensburg, Walter Sisulu UniversityWalter Sisulu University, South Africa
Issue SectionLetters to the Editor
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