Mohamad Adib Jaafar, Periodontal Specialist Clinic of Jalan Perak, Ministry of Health Malaysia, 11600, Penang, Malaysia.Follow
Esther Voo Vui Ching, Periodontal Specialist Clinic of Mak Mandin, Ministry of Health Malaysia, 13400, Penang, Malaysia.
Sharul Nisha Ali, Periodontal Specialist Clinic of Mak Mandin, Ministry of Health Malaysia, 13400, Penang, Malaysia.
Jeyanthi Subramaniam, Sungai Dua Dental Clinic, Ministry of Health Malaysia, 13800, Butterworth, Penang, Malaysia.
Yuhaniz Ahmad Yaziz, Periodontal Specialist Unit, Kota Setar Dental Specialist Clinic, Lebuhraya Darul Aman, Ministry of Health Malaysia, 05100, Kedah, Malaysia.

Objective: The purpose of this study was to determine the adjunctive clinical effect of hyaluronic acid (HA) in the non-surgical treatment of subjects with residual pockets (≥ 6 mm) at the maintenance phase. Methods: 36 systemically healthy subjects in the periodontal maintenance phase were included in this 3-month randomized clinical trial. Subjects received a course of full-mouth, scaling and root debridement (SRD). In the test group (n = 18), HA 0.8% was applied subgingivally immediately after SRD. The control group (n = 18) was treated with SRD only. Subjects in both groups were required to apply HA 0.2% twice a day for 2 weeks. Clinical parameters collected at baseline and 3 months post-treatment were periodontal pocket depth (PPD), bleeding on probing (BOP), and clinical attachment level (CAL). Results: In both groups, all parameters were significantly reduced (p Conclusion: The overall results show that treatment with HA 0.8% has a potential improvement in periodontal health.

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