Nakamura T, Matsumine A, Matsubara T, Asanuma K, Uchida A, Sudo A (2011) The symptom-to-diagnosis delay in soft tissue sarcoma influence the overall survival and the development of distant metastasis. J Surg Oncol 104(7):771–775. https://doi.org/10.1002/jso.22006

Article  PubMed  Google Scholar 

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines): soft tissue sarcoma. (Version 3.2023). National Comprehensive Cancer Network, Inc 2023 All rights reserved. https://www.nccn.org/professionals/physician_gls/pdf/sarcoma.pdf. Accessed 04/02/2024

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines): bone cancer. (Version 2.2024). National Comprehensive Cancer Network, Inc 2024 All rights reserved. https://www.nccn.org/professionals/physician_gls/pdf/bone.pdf. Accessed 04/02/2024

Curtis GL, Lawrenz JM, George J et al (2018) Adult soft tissue sarcoma and time to treatment initiation: an analysis of the National Cancer Database. J Surg Oncol 117(8):1776–1785. https://doi.org/10.1002/jso.25095

Article  PubMed  Google Scholar 

Trama A, Badalamenti G, Baldi GG et al (2019) Soft tissue sarcoma in Italy: from epidemiological data to clinical networking to improve patient care and outcomes. Cancer Epidemiol 59:258–264. https://doi.org/10.1016/j.canep.2019.02.012

Article  PubMed  Google Scholar 

George A, Grimer R (2012) Early symptoms of bone and soft tissue sarcomas: could they be diagnosed earlier? Ann R Coll Surg Engl 94(4):261–266. https://doi.org/10.1308/003588412x13171221590016

Article  CAS  PubMed  PubMed Central  Google Scholar 

Burningham Z, Hashibe M, Spector L, Schiffman JD (2012) The epidemiology of sarcoma. Clin Sarcoma Res 2(1):14. https://doi.org/10.1186/2045-3329-2-14

Article  PubMed  PubMed Central  Google Scholar 

Siegel RL, Giaquinto AN, Jemal A (2024) Cancer statistics, 2024. CA Cancer J Clin 74(1):12–49. https://doi.org/10.3322/caac.21820

Article  PubMed  Google Scholar 

WHO Classification of Tumours Editorial Board. Soft tissue and bone tumours [Internet] (2020) Lyon (France): international agency for research on cancer (WHO classification of tumours series, 5th ed; vol 3). https://tumourclassification.iarc.who.int/chapters/33. Accessed 04/02/2024

González IA, Stewart DR, Schultz KAP, Field AP, Hill DA, Dehner LP (2022) DICER1 tumor predisposition syndrome: an evolving story initiated with the pleuropulmonary blastoma. Mod Pathol 35(1):4–22. https://doi.org/10.1038/s41379-021-00905-8

Article  CAS  PubMed  Google Scholar 

Berrington de Gonzalez A, Kutsenko A, Rajaraman P (2012) Sarcoma risk after radiation exposure. Clin Sarcoma Res 2(1):18. https://doi.org/10.1186/2045-3329-2-18

Article  PubMed  PubMed Central  Google Scholar 

Thomas DM, Savage SA, Bond GL (2012) Hereditary and environmental epidemiology of sarcomas. Clin Sarcoma Res 2(1):13. https://doi.org/10.1186/2045-3329-2-13

Article  PubMed  PubMed Central  Google Scholar 

McBride KA, Schlub TE, Ballinger ML, Thomas DM, Tattersall MH (2016) International survey of awareness of genetic risk in the clinical sarcoma community. Asia Pac J Clin Oncol 12(2):133–142. https://doi.org/10.1111/ajco.12457

Article  PubMed  Google Scholar 

Brouns F, Stas M, De Wever I (2003) Delay in diagnosis of soft tissue sarcomas. Eur J Surg Oncol 29(5):440–445. https://doi.org/10.1016/s0748-7983(03)00006-4

Article  CAS  PubMed  Google Scholar 

Sharma A, Schwartz RA (2012) Stewart-Treves syndrome: pathogenesis and management. J Am Acad Dermatol 67(6):1342–1348. https://doi.org/10.1016/j.jaad.2012.04.028

Article  PubMed  Google Scholar 

Nandra R, Forsberg J, Grimer R (2015) If your lump is bigger than a golf ball and growing, think sarcoma. Eur J Surg Oncol 41(10):1400–1405. https://doi.org/10.1016/j.ejso.2015.05.017

Article  CAS  PubMed  Google Scholar 

Chotel F, Unnithan A, Chandrasekar CR, Parot R, Jeys L, Grimer RJ (2008) Variability in the presentation of synovial sarcoma in children: a plea for greater awareness. J Bone Joint Surg Br 90(8):1090–1096. https://doi.org/10.1302/0301-620x.90b8.19815

Article  CAS  PubMed  Google Scholar 

Rædkjær M, Maretty-Kongstad K, Baad-Hansen T et al (2019) Use of healthcare services two years before diagnosis in Danish sarcoma patients, 2000–2013. Sarcoma 2019:8108590. https://doi.org/10.1155/2019/8108590

Article  PubMed  PubMed Central  Google Scholar 

Harrison WD, Sargazi N, Yin Q, Chandrasekar CR (2016) Delayed diagnosis in primary care-the main cause of sarcoma litigation in the United Kingdom. J Surg Oncol 113(4):361–363. https://doi.org/10.1002/jso.24149

Article  PubMed  Google Scholar 

Hwang R, Park HY, Sheppard W, Bernthal NM (2020) Delayed diagnosis is the primary cause of sarcoma litigation: analysis of malpractice claims in the United States. Clin Orthop Relat Res 478(10):2239–2253. https://doi.org/10.1097/corr.0000000000001340

Article  PubMed  PubMed Central  Google Scholar 

Styring E, Billing V, Hartman L et al (2012) Simple guidelines for efficient referral of soft-tissue sarcomas: a population-based evaluation of adherence to guidelines and referral patterns. J Bone Joint Surg Am 94(14):1291–1296. https://doi.org/10.2106/jbjs.K.01271

Article  CAS  PubMed  Google Scholar 

Fossum CC, Breen WG, Sun PY, Retzlaff AA, Okuno SH (2020) Assessment of familiarity with work-up guidelines for bone and soft tissue sarcoma among primary care practitioners in Minnesota. Mayo Clin Proc Innov Qual Outcomes 4(2):143–149. https://doi.org/10.1016/j.mayocpiqo.2019.12.002

Article  PubMed  PubMed Central  Google Scholar 

Younger E, Husson O, Bennister L et al (2018) Age-related sarcoma patient experience: results from a national survey in England. BMC Cancer 18(1):991. https://doi.org/10.1186/s12885-018-4866-8

Article  PubMed  PubMed Central  Google Scholar 

Belzarena AC, Binitie O, Letson GD, Joyce DM. 2024. Unplanned sarcoma excisions: understanding how they happen. J Am Acad Orthop Surg Glob Res Rev 8(1)https://doi.org/10.5435/JAAOSGlobal-D-23-00176

Lawrenz JM, Curtis GL, Styron JF et al (2018) Adult primary bone sarcoma and time to treatment initiation: an analysis of the National Cancer Database. Sarcoma 2018:1728302. https://doi.org/10.1155/2018/1728302

Article  PubMed  PubMed Central  Google Scholar 

Clark MA, Thomas JM (2005) Delay in referral to a specialist soft-tissue sarcoma unit. Eur J Surg Oncol 31(4):443–448. https://doi.org/10.1016/j.ejso.2004.11.016

Article  CAS  PubMed  Google Scholar 

Minnesota State Demographic Center (2017) Greater Minnesota: refined & revisited. https://mn.gov/admin/demography/reports-resources/greater-mn-refined-and-revisited.jsp. Accessed 04/07/2024

United States Census Bureau. QuickFacts Minnesota. https://www.census.gov/quickfacts/fact/table/MN/RHI225222#RHI225222. Accessed 04/07/2024

Szucs Z, Davidson D, Wong HH et al (2016) A comprehensive single institutional review of 2 years in a designated fast-track sarcoma diagnostic clinic linked with a sarcoma specialist advisory group: meeting the target but failing the task? Sarcoma 2016:6032606. https://doi.org/10.1155/2016/6032606

Article  PubMed  PubMed Central  Google Scholar 

Kasper B, Lecointe-Artzner E, Wait S et al (2018) Working to improve the management of sarcoma patients across Europe: a policy checklist. BMC Cancer 18(1):424. https://doi.org/10.1186/s12885-018-4320-y

Article  PubMed  PubMed Central  Google Scholar 

Mathoulin-Pélissier S, Chevreau C, Bellera C et al (2014) Adherence to consensus-based diagnosis and treatment guidelines in adult soft-tissue sarcoma patients: a French prospective population-based study. Ann Oncol 25(1):225–231. https://doi.org/10.1093/annonc/mdt407

Article  PubMed  Google Scholar 

Jansen-Landheer ML, Krijnen P, Oostindiër MJ et al (2009) Improved diagnosis and treatment of soft tissue sarcoma patients after implementation of national guidelines: a population-based study. Eur J Surg Oncol 35(12):1326–1332. https://doi.org/10.1016/j.ejso.2009.05.002

Article  CAS  PubMed  Google Scholar