Advancements of prodrug technologies for enhanced drug selectivity in pharmacotherapies

Wang X, Ryu D, Houtkooper RH, Auwerx J (2015) Antibiotic use and abuse: a threat to mitochondria and chloroplasts with impact on research, health, and environment. BioEssays 37(10):1045–1053

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wilhelm S, Tavares AJ, Dai Q, Ohta S, Audet J, Dvorak HF, Chan WCW (2016) Analysis of nanoparticle delivery to tumours. Nat Rev Mater 1(5):16014

Article  CAS  Google Scholar 

Velema WA, Szymanski W, Feringa BL (2014) Photopharmacology: Beyond proof of principle. J Am Chem Soc 136(6):2178–2191

Article  CAS  PubMed  Google Scholar 

Tibbitt MW, Dahlman JE, Langer R (2016) Emerging frontiers in drug delivery. J Am Chem Soc 138(3):704–717

Article  CAS  PubMed  Google Scholar 

Li Z, Xiao C, Yong T, Li Z, Gan L, Yang X (2020) Influence of nanomedicine mechanical properties on tumor targeting delivery. Chem Soc Rev 49(8):2273–2290

Article  CAS  PubMed  Google Scholar 

Kang H, Rho S, Stiles WR, Hu S, Baek Y, Hwang DW, Kashiwagi S, Kim MS, Choi HS (2020) Size-dependent EPR effect of polymeric nanoparticles on tumor targeting. Adv Healthc Mater 9(1):1901223

Article  CAS  Google Scholar 

Song X, Zhu W, Ge X, Li R, Li S, Chen X, Song J, Xie J, Chen X, Yang H (2021) A new class of NIR-II gold nanocluster-based protein biolabels for in vivo tumor-targeted imaging. Angew Chem Int Ed 60(3):1306–1312

Article  CAS  Google Scholar 

Sindhwani S, Syed AM, Ngai J, Kingston BR, Maiorino L, Rothschild J, MacMillan P, Zhang Y, Rajesh NU, Hoang T, Wu JLY, Wilhelm S, Zilman A, Gadde S, Sulaiman A, Ouyang B, Lin Z, Wang L, Egeblad M, Chan WCW (2020) The entry of nanoparticles into solid tumours. Nat Mater 19(5):566–575

Article  CAS  PubMed  Google Scholar 

Badrigilan S, Choupani J, Khanbabaei H, Hoseini-Ghahfarokhi M, Webster TJ, Tayebi L (2020) Bismuth-based nanomaterials: recent advances in tumor targeting and synergistic cancer therapy techniques. Adv Healthc Mater 9(7):1901695

Article  CAS  Google Scholar 

Wan X, Song L, Pan W, Zhong H, Li N, Tang B (2020) Tumor-targeted cascade nanoreactor based on metal-organic frameworks for synergistic ferroptosis-starvation anticancer therapy. ACS Nano 14(9):11017–11028

Article  CAS  PubMed  Google Scholar 

Albert A (1958) Chemical aspects of selective toxicity. Nature 182(4633):421–423

Article  CAS  PubMed  Google Scholar 

Yao Q, Lin F, Fan X, Wang Y, Liu Y, Liu Z, Jiang X, Chen PR, Gao Y (2018) Synergistic enzymatic and bioorthogonal reactions for selective prodrug activation in living systems. Nat Commun 9(1):5032

Article  PubMed  PubMed Central  Google Scholar 

Jeon J, Yoon B, Dey A, Song SH, Li Y, Joo H, Park JH (2023) Self-immolative polymer-based immunogenic cell death inducer for regulation of redox homeostasis. Biomaterials 295:122064

Article  CAS  PubMed  Google Scholar 

Wan J, Huang L, Cheng J, Qi H, Jin J, Wang H (2021) Balancing the stability and drug activation in adaptive nanoparticles potentiates chemotherapy in multidrug-resistant cancer. Theranostics 11(9):4137–4154

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yu FZ, Tu YL, Luo SW, Xiao X, Yao W, Jiang ML, Jiang XQ, Yang RM, Yuan YY (2021) Dual-drug Backboned Polyprodrug with a Predefined Drug Combination for synergistic chemotherapy. Nano Lett 21(5):2216–2223

Article  CAS  PubMed  Google Scholar 

Krasnovskaya OO, Malinnikov VM, Dashkova NS, Gerasimov VM, Grishina IV, Kireev II, Lavrushkina SV, Panchenko PA, Zakharko MA, Ignatov PA, Fedorova OA, Jonusauskas G, Skvortsov DA, Kovalev SS, Beloglazkina EK, Zyk NV, Majouga AG (2019) Thiourea Modified Doxorubicin: a perspective pH-Sensitive Prodrug. Bioconjug Chem 30(3):741–750

Article  CAS  PubMed  Google Scholar 

Wang K, Xiao X, Liu Y, Zong Q, Tu Y, Yuan Y (2022) Self-immolative polyprodrug-based tumor-specific cascade amplificated drug release nanosystem for orchestrated synergistic cancer therapy. Biomaterials 289:121803

Article  CAS  PubMed  Google Scholar 

Huo M, Yuan J, Tao L, Wei Y (2014) Redox-responsive polymers for drug delivery: from molecular design to applications. Polym Chem 5(5):1519–1528

Article  CAS  Google Scholar 

Luo X, Gong X, Su L, Lin H, Yang Z, Yan X, Gao J (2021) Activatable Mitochondria-Targeting Organoarsenic Prodrugs for Bioenergetic Cancer Therapy. Angew Chem Int Ed 60(3):1403–1410

Article  CAS  Google Scholar 

Li X, Jeon Y-H, Kwon N, Park J-G, Guo T, Kim H-R, Huang J-D, Lee D-S, Yoon J (2021) In vivo-assembled phthalocyanine/albumin supramolecular complexes combined with a hypoxia-activated prodrug for enhanced photodynamic immunotherapy of cancer. Biomaterials 266:120430

Article  CAS  PubMed  Google Scholar 

Dey A, Jeon J, Yoon B, Li Y, Park JH (2023) Cascade-amplified self-immolative polymeric prodrug for cancer therapy by disrupting redox homeostasis. J Controlled Release 358:555–565

Article  CAS  Google Scholar 

Lavis LD (2008) Ester bonds in prodrugs. ACS Chem Biol 3(4):203–206

Article  CAS  PubMed  Google Scholar 

Patchett A (1984) The chemistry of enalapril. Br J Clin Pharmacol 18(S2):201S–207S

Article  PubMed  PubMed Central  Google Scholar 

Wang Y, Luo Q, Sun R, Zha G, Li X, Shen Z, Zhu W (2014) Acid-triggered drug release from micelles based on amphiphilic oligo(ethylene glycol)–doxorubicin alternative copolymers. J Mater Chem B 2(43):7612–7619

Article  CAS  PubMed  Google Scholar 

Zhang X, Zhao M, Cao N, Qin W, Zhao M, Wu J, Lin D (2020) Construction of a tumor microenvironment pH-responsive cleavable PEGylated hyaluronic acid nano-drug delivery system for colorectal cancer treatment. Biomater Sci 8(7):1885–1896

Article  CAS  PubMed  Google Scholar 

Kalia J, Raines RT (2008) Hydrolytic stability of hydrazones and oximes. Angew Chem Int Ed 47(39):7523–7526

Article  CAS  Google Scholar 

Che J, Najer A, Blakney AK, McKay PF, Bellahcene M, Winter CW, Sintou A, Tang J, Keane TJ, Schneider MD, Shattock RJ, Sattler S, Stevens MM (2020) Neutrophils enable local and non-invasive liposome delivery to inflamed skeletal muscle and ischemic heart. Adv Mater 32(48):2003598

Article  CAS  Google Scholar 

Liang J, Liu B (2016) ROS-responsive drug delivery systems. Bioeng Translational Med 1(3):239–251

Article  CAS  Google Scholar 

Napoli A, Valentini M, Tirelli N, Müller M, Hubbell JA (2004) Oxidation-responsive polymeric vesicles. Nat Mater 3(3):183–189

Article  CAS  PubMed  Google Scholar 

Dong C, Zhou Q, Xiang J, Liu F, Zhou Z, Shen Y (2020) Self-assembly of oxidation-responsive polyethylene glycol-paclitaxel prodrug for cancer chemotherapy. J Controlled Release 321:529–539

Article  CAS  Google Scholar 

Pei P, Sun C, Tao W, Li J, Yang X, Wang J (2019) ROS-sensitive thioketal-linked polyphosphoester-doxorubicin conjugate for precise phototriggered locoregional chemotherapy. Biomaterials 188:74–82

Article  CAS  PubMed  Google Scholar 

Huang L, Wan J, Wu H, Chen X, Bian Q, Shi L, Jiang X, Yuan A, Gao J, Wang H (2021) Quantitative self-assembly of photoactivatable small molecular prodrug cocktails for safe and potent cancer chemo-photodynamic therapy. Nano Today 36:101030

Article 

留言 (0)

沒有登入
gif