1   State Key Laboratory of Experimental Hematology, Pediatric Hematology and Oncology Center, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China

2   Tianjin Institutes of Health Science, Tianjin, China

,

1   State Key Laboratory of Experimental Hematology, Pediatric Hematology and Oncology Center, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China

2   Tianjin Institutes of Health Science, Tianjin, China

,

Ying Li

1   State Key Laboratory of Experimental Hematology, Pediatric Hematology and Oncology Center, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China

3   State Key Laboratory of Experimental Hematology, Department of Radiology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

,

Xiaoming Liu

1   State Key Laboratory of Experimental Hematology, Pediatric Hematology and Oncology Center, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China

2   Tianjin Institutes of Health Science, Tianjin, China

,

Lixian Chang

1   State Key Laboratory of Experimental Hematology, Pediatric Hematology and Oncology Center, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China

2   Tianjin Institutes of Health Science, Tianjin, China

,

Beibei Zhao

1   State Key Laboratory of Experimental Hematology, Pediatric Hematology and Oncology Center, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China

2   Tianjin Institutes of Health Science, Tianjin, China

,

Li Zhang

1   State Key Laboratory of Experimental Hematology, Pediatric Hematology and Oncology Center, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China

2   Tianjin Institutes of Health Science, Tianjin, China

,

Yao Zou

1   State Key Laboratory of Experimental Hematology, Pediatric Hematology and Oncology Center, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China

2   Tianjin Institutes of Health Science, Tianjin, China

,

Min Ruan

1   State Key Laboratory of Experimental Hematology, Pediatric Hematology and Oncology Center, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China

2   Tianjin Institutes of Health Science, Tianjin, China

,

Xiaofan Zhu

1   State Key Laboratory of Experimental Hematology, Pediatric Hematology and Oncology Center, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China

2   Tianjin Institutes of Health Science, Tianjin, China

This work was supported by the CAMS Innovation Fund for Medical Sciences (2022-I2M-1-022), the National Natural Science Foundation of China (82270144).