Background: Since human papillomavirus (HPV) infection is known as one of the main causes of cervical cancer, medical researchers pay significant attention to this issue2. The current study applies the bibliometric method to identify the trends and advancements of research on HPV worldwide.

Methods: This descriptive study was conducted using a bibliometric approach. All HPV-related scientific publications in the Web of Science database until 2022, August 30 were included in the statistical population. The Bibliometrix package of the R programming language was used to analyze the data.

Results: In the field of HPV, a total of 45,657 scientific publications were retrieved, the majority of which were articles. The countries with the highest publications were the USA (45,954 document), China (9977), and UK (6652). The words “Infection,” “Cancer,” and “Women” are the most important keywords of scientific publications on HPV. “Cancer,” “infection,” and “women” are the more developed and essential in HPV subject area. “Protein,” “gene-expression,” and “human-keratinocytes” are in this quadrant. “DNA,” “squamous-cell carcinoma,” and “head” keywords are basic themes in the HPV subject area. “Human-papillomavirus vaccination,” “knowledge,” and “attitude” are in this quadrant.

Conclusion: The study suggests the need to enhance the focus on global and public health aspects within HPV research to encourage greater participation from various countries in international research endeavors.

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