Podolec P. Rare cardiovascular diseases. Eur Heart J. 2017;38(43):3190–2.

Article  PubMed  Google Scholar 

Ciurică S, Lopez-Sublet M, Loeys BL, Radhouani I, Natarajan N, Vikkula M, et al. Arterial tortuosity. Hypertension. 2019;73(5):951–60.

Article  PubMed  Google Scholar 

Del Corso L, Moruzzo D, Conte B, Agelli M, Romanelli AM, Pastine F, et al. Tortuosity, kinking, and coiling of the carotid artery: expression of atherosclerosis or aging? Angiology. 1998;49(5):361–71.

Article  PubMed  Google Scholar 

Cha KS, Kim MH, Kim HJ. Prevalence and clinical predictors of severe tortuosity of right subclavian artery in patients undergoing transradial coronary angiography. Am J Cardiol. 2003;92(10):1220–2.

Article  PubMed  Google Scholar 

Hutchins GM, Bulkley BH, Miner MM, Boitnott JK. Correlation of age and heart weight with tortuosity and caliber of normal human coronary arteries. Am Heart J. 1977;94(2):196–202.

Article  CAS  PubMed  Google Scholar 

Ágg B, Szilveszter B, Daradics N, Benke K, Stengl R, Kolossváry M, et al. Increased visceral arterial tortuosity in Marfan syndrome. Orphanet J Rare Dis. 2020;15(1):91.

Article  PubMed  PubMed Central  Google Scholar 

Morris SA. Arterial tortuosity in genetic arteriopathies. Curr Opin Cardiol. 2015;30(6):587–93.

Article  PubMed  PubMed Central  Google Scholar 

Naunheim MR, Walcott BP, Nahed BV, MacRae CA, Levinson JR, Ogilvy CS. Arterial tortuosity syndrome with multiple intracranial aneurysms: a case report. Arch Neurol. 2011;68(3):369–71.

Article  PubMed  Google Scholar 

Pletcher BA, Fox JE, Boxer RA, Singh S, Blumenthal D, Cohen T, et al. Four sibs with arterial tortuosity: description and review of the literature. Am J Med Genet. 1996;66(2):121–8.

Article  CAS  PubMed  Google Scholar 

Subramanyan R, Sridhar A, Cherian K. Arterial tortuosity syndrome. Pediatr Cardiol. 2009;30(4):555–6.

Article  PubMed  Google Scholar 

Franceschini P, Guala A, Licata D, Di Cara G, Franceschini D. Arterial tortuosity syndrome. Am J Med Genet. 2000;91(2):141–3.

Article  CAS  PubMed  Google Scholar 

Beyens A, Albuisson J, Boel A, Al-Essa M, Al-Manea W, Bonnet D, et al. Arterial tortuosity syndrome: 40 new families and literature review. Genet Med. 2018;20(10):1236–45.

Article  PubMed  Google Scholar 

Ritelli M, Drera B, Vicchio M, Puppini G, Biban P, Pilati M, et al. Arterial tortuosity syndrome in two Italian paediatric patients. Orphanet J Rare Dis. 2009;4:20.

Article  PubMed  PubMed Central  Google Scholar 

Han HC. Twisted blood vessels: symptoms, etiology and biomechanical mechanisms. J Vasc Res. 2012;49(3):185–97.

Article  PubMed  PubMed Central  Google Scholar 

Pape LA, Tsai TT, Isselbacher EM, Oh JK, O’Gara PT, Evangelista A, et al. Aortic diameter >or = 5.5 cm is not a good predictor of type A aortic dissection: observations from the International Registry of Acute Aortic Dissection (IRAD). Circulation. 2007;116(10):1120–7.

Article  PubMed  Google Scholar 

Parish LM, Gorman JH III, Kahn S, Plappert T, St. John-Sutton MG, Bavaria JE, et al. Aortic size in acute type A dissection: implications for preventive ascending aortic replacement☆. Eur J Cardiothorac Surg. 2009;35(6):941–6.

Article  PubMed  Google Scholar 

Morris SA, Orbach DB, Geva T, Singh MN, Gauvreau K, Lacro RV. Increased vertebral artery tortuosity index is associated with adverse outcomes in children and young adults with connective tissue disorders. Circulation. 2011;124(4):388–96.

Article  PubMed  Google Scholar 

Eleid MF, Guddeti RR, Tweet MS, Lerman A, Singh M, Best PJ, et al. Coronary artery tortuosity in spontaneous coronary artery dissection. Circulation. 2014;7(5):656–62.

PubMed  Google Scholar 

Jondeau G, Ropers J, Regalado E, Braverman A, Evangelista A, Teixedo G, et al. International Registry of Patients Carrying TGFBR1 or TGFBR2 mutations. Circulation. 2016;9(6):548–58.

CAS  PubMed  Google Scholar 

Franken R, El Morabit A, de Waard V, Timmermans J, Scholte AJ, van den Berg MP, et al. Increased aortic tortuosity indicates a more severe aortic phenotype in adults with Marfan syndrome. Int J Cardiol. 2015;194:7–12.

Article  PubMed  Google Scholar 

Chu LC, Haroun RR, Beaulieu RJ, Black JH 3rd, Dietz HC, Fishman EK. Carotid artery tortuosity index is associated with the need for early aortic root replacement in patients with Loeys-Dietz syndrome. J Comput Assist Tomogr. 2018;42(5):747–53.

Article  PubMed  Google Scholar 

Callewaert B, De Paepe A, Coucke P, et al. Arterial tortuosity syndrome. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Mirzaa G, et al., editors. GeneReviews(®). Seattle: University of Washington, Seattle; 1993. Copyright © 1993-2021, University of Washington, Seattle. GeneReviews is a registered trademark of the University of Washington, Seattle. All rights reserved.

Google Scholar 

Callewaert BL, Willaert A, Kerstjens-Frederikse WS, De Backer J, Devriendt K, Albrecht B, et al. Arterial tortuosity syndrome: clinical and molecular findings in 12 newly identified families. Hum Mutat. 2008;29(1):150–8.

Article  CAS  PubMed  Google Scholar 

Devereux RB, de Simone G, Arnett DK, Best LG, Boerwinkle E, Howard BV, et al. Normal limits in relation to age, body size and gender of two-dimensional echocardiographic aortic root dimensions in persons ≥15 years of age. Am J Cardiol. 2012;110(8):1189–94.

Article  PubMed  PubMed Central  Google Scholar 

Malek S, Reinhold EJ, Pearce GS. The Beighton Score as a measure of generalised joint hypermobility. Rheumatol Int. 2021;41(10):1707–16.

Article  PubMed  PubMed Central  Google Scholar 

Dougherty G, Varro J. A quantitative index for the measurement of the tortuosity of blood vessels. Med Eng Phys. 2000;22(8):567–74.

Article  CAS  PubMed  Google Scholar 

Alicioglu B, Gulekon N, Akpinar S. Age-related morphologic changes of the vertebral artery in the transverse process. Analysis by multidetector computed tomography angiography. Spine J. 2015;15(9):1981–7.

Article  PubMed  Google Scholar 

Sugawara J, Hayashi K, Yokoi T, Tanaka H. Age-associated elongation of the ascending aorta in adults. JACC Cardiovasc Imaging. 2008;1(6):739–48.

Article  PubMed  Google Scholar 

Rylski B, Desjardins B, Moser W, Bavaria JE, Milewski RK. Gender-related changes in aortic geometry throughout life. Eur J Cardiothorac Surg. 2014;45(5):805–11.

Article  PubMed  Google Scholar 

Craiem D, Chironi G, Redheuil A, Casciaro M, Mousseaux E, Simon A, et al. Aging impact on thoracic aorta 3D morphometry in intermediate-risk subjects: looking beyond coronary arteries with non-contrast cardiac CT. Ann Biomed Eng. 2012;40(5):1028–38.

Article  PubMed  Google Scholar 

Adriaans BP, Heuts S, Gerretsen S, Cheriex EC, Vos R, Natour E, et al. Aortic elongation part I: the normal aortic ageing process. Heart. 2018;104(21):1772–7.

Article  PubMed  Google Scholar 

Belvroy VM, de Beaufort HWL, van Herwaarden JA, Bismuth J, Moll FL, Trimarchi S. Tortuosity of the descending thoracic aorta: normal values by age. PLoS One. 2019;14(4):e0215549.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Martins HFG, Mayer A, Batista P, Soares F, Almeida V, Pedro AJ, et al. Morphological changes of the internal carotid artery: prevalence and characteristics. A clinical and ultrasonographic study in a series of 19 804 patients over 25 years old. Eur J Neurol. 2018;25(1):171–7.

Article  CAS  PubMed