Khalil, D. N., Smith, E. L., Brentjens, R. J. & Wolchok, J. D. The future of cancer treatment: immunomodulation, CARs and combination immunotherapy. Nat. Rev. Clin. Oncol. 13, 273–290 (2016).
Article CAS PubMed PubMed Central Google Scholar
Gide, T. N., Wilmott, J. S., Scolyer, R. A. & Long, G. V. Primary and acquired resistance to immune checkpoint inhibitors in metastatic melanoma. Clin. Cancer Res. 24, 1260–1270 (2018).
Article CAS PubMed Google Scholar
Brahmer, J. R. et al. The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of non-small cell lung cancer (NSCLC). J. Immunother. Cancer 6, 75 (2018).
Article PubMed PubMed Central Google Scholar
Fehrenbacher, L. et al. Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial. Lancet 387, 1837–1846 (2016).
Article CAS PubMed Google Scholar
Gandhi, L. et al. Pembrolizumab plus chemotherapy in metastatic non-small-cell lung cancer. N. Engl. J. Med. 378, 2078–2092 (2018).
Article CAS PubMed Google Scholar
Gopalakrishnan, V., Helmink, B. A., Spencer, C. N., Reuben, A. & Wargo, J. A. The influence of the gut microbiome on cancer, immunity, and cancer immunotherapy. Cancer Cell 33, 570–580 (2018).
Article CAS PubMed PubMed Central Google Scholar
Helmink, B. A., Khan, M. A. W., Hermann, A., Gopalakrishnan, V. & Wargo, J. A. The microbiome, cancer, and cancer therapy. Nat. Med. 25, 377–388 (2019).
Article CAS PubMed Google Scholar
Zitvogel, L., Ma, Y., Raoult, D., Kroemer, G. & Gajewski, T. F. The microbiome in cancer immunotherapy: diagnostic tools and therapeutic strategies. Science 359, 1366–1370 (2018).
Article CAS PubMed Google Scholar
Garrett, W. S. Cancer and the microbiota. Science 348, 80–86 (2015).
Article CAS PubMed PubMed Central Google Scholar
Park, E. M. et al. Targeting the gut and tumor microbiota in cancer. Nat. Med. 28, 690–703 (2022).
Article CAS PubMed Google Scholar
Sepich-Poore, G. D. et al. The microbiome and human cancer. Science 371, eabc4552 (2021).
Article CAS PubMed PubMed Central Google Scholar
Yang, L., Li, A., Wang, Y. & Zhang, Y. Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy. Signal. Transduct. Target. Ther. 8, 35 (2023).
Article CAS PubMed PubMed Central Google Scholar
Nejman, D. et al. The human tumor microbiome is composed of tumor type-specific intracellular bacteria. Science 368, 973–980 (2020).
Article CAS PubMed PubMed Central Google Scholar
Poore, G. D. et al. Microbiome analyses of blood and tissues suggest cancer diagnostic approach. Nature 579, 567–574 (2020).
Article CAS PubMed PubMed Central Google Scholar
Parhi, L. et al. Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression. Nat. Commun. 11, 3259 (2020).
Article CAS PubMed PubMed Central Google Scholar
Heymann, C. J. F., Bard, J. M., Heymann, M. F., Heymann, D. & Bobin-Dubigeon, C. The intratumoral microbiome: characterization methods and functional impact. Cancer Lett. 522, 63–79 (2021).
Article CAS PubMed Google Scholar
Fessler, J., Matson, V. & Gajewski, T. F. Exploring the emerging role of the microbiome in cancer immunotherapy. J. Immunother. Cancer 7, 108 (2019).
Article PubMed PubMed Central Google Scholar
Xue, C. et al. Current understanding of the intratumoral microbiome in various tumors. Cell Rep. Med. 4, 100884 (2023).
Article CAS PubMed PubMed Central Google Scholar
Fulbright, L. E., Ellermann, M. & Arthur, J. C. The microbiome and the hallmarks of cancer. PLoS Pathog. 13, e1006480 (2017).
Article PubMed PubMed Central Google Scholar
Frankel, A. E. et al. Metagenomic shotgun sequencing and unbiased metabolomic profiling identify specific human gut microbiota and metabolites associated with immune checkpoint therapy efficacy in melanoma patients. Neoplasia 19, 848–855 (2017).
Article CAS PubMed PubMed Central Google Scholar
Riquelme, E. et al. Tumor microbiome diversity and composition influence pancreatic cancer outcomes. Cell 178, 795–806.e12 (2019).
Article CAS PubMed PubMed Central Google Scholar
Ebbell, B. The Papyrus Ebers, The Greatest Egyptian Medical Document (Levin & Munksgaard; H. Milford; Oxford University Press, 1937).
Kang, S. R., Nguyen, D. H., Yoo, S. W. & Min, J. J. Bacteria and bacterial derivatives as delivery carriers for immunotherapy. Adv. Drug Deliv. Rev. 181, 114085 (2022).
Article CAS PubMed Google Scholar
Nguyen, D. H., Chong, A., Hong, Y. & Min, J. J. Bioengineering of bacteria for cancer immunotherapy. Nat. Commun. 14, 3553 (2023).
Article CAS PubMed PubMed Central Google Scholar
Zhou, S., Gravekamp, C., Bermudes, D. & Liu, K. Tumour-targeting bacteria engineered to fight cancer. Nat. Rev. Cancer 18, 727–743 (2018).
Article CAS PubMed PubMed Central Google Scholar
Forbes, N. S. Engineering the perfect (bacterial) cancer therapy. Nat. Rev. Cancer 10, 785–794 (2010).
Article CAS PubMed PubMed Central Google Scholar
Cogdill, A. P., Gaudreau, P. O., Arora, R., Gopalakrishnan, V. & Wargo, J. A. The impact of intratumoral and gastrointestinal microbiota on systemic cancer therapy. Trends Immunol. 39, 900–920 (2018).
Article CAS PubMed Google Scholar
Xie, Y. et al. Microbiota in tumors: from understanding to application. Adv. Sci. 9, e2200470 (2022).
Fu, A. et al. Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer. Cell 185, 1356–1372.e26 (2022).
Article CAS PubMed Google Scholar
Wang, M., Yu, F. & Li, P. Intratumor microbiota in cancer pathogenesis and immunity: from mechanisms of action to therapeutic opportunities. Front. Immunol. 14, 1269054 (2023).
Article CAS PubMed PubMed Central Google Scholar
van Elsland, D. & Neefjes, J. Bacterial infections and cancer. EMBO Rep. 19, e46632 (2018).
留言 (0)