Humane Endpoint: Example from a Murine Model of Disseminated Sporotrichosis

Gyssens IC (2019) Animal models for research in human infectious diseases CMI editorial policy. Clin Microbiol Infect 25(6):649–650. https://doi.org/10.1016/j.cmi.2019.04.010

Article  CAS  PubMed  Google Scholar 

National Research Council (US) (2011) Committee for the update of the guide for the care and use of laboratory animals. Guide for the care and use of laboratory animals, 8th edn. National Academies Press, Washington DC

Google Scholar 

Zhang X, Kumstel S, Tang G et al (2020) A rational approach of early humane endpoint determination in a murine model for cholestasis. Altex 37(2):197–207. https://doi.org/10.14573/altex.1909111

Article  CAS  PubMed  Google Scholar 

Hankenson FC, Ruskoski N, van Saun M et al (2013) Weight loss and reduced body temperature determine humane endpoints in a mouse model of ocular herpesvirus infection. J Am Assoc Lab Anim Sci 52(3):277–285

CAS  PubMed  PubMed Central  Google Scholar 

Sanders CJ, Johnson B, Frevert CW et al (2013) Intranasal influenza infection of mice and methods to evaluate progression and outcome. Method Mol Biol 1031:177–188. https://doi.org/10.1007/978-1-62703-481-4_20

Article  CAS  Google Scholar 

Boehm CA, Nemzek JA (2021) Analgesia and humane endpoints for rodents in sepsis research. Method Mol Biol 2321:221–229. https://doi.org/10.1007/978-1-0716-1488-4:19

Article  CAS  Google Scholar 

World Health Organization (2022) WHO fungal priority pathogens list to guide research, development and public health action

WHO (2020) Ending the neglect to attain the sustainable development goals: a road map for neglected tropical diseases 2021–2030. World Health Organization, Geneva

Google Scholar 

Rabello VBS, Almeida MA, Bernardes-Engemann AR et al (2022) The historical burden of sporotrichosis in brazil: a systematic review of cases reported from 1907 to 2020. Braz J Microbiol 53(1):231–244. https://doi.org/10.1007/s42770-021-00658-1

Article  PubMed  Google Scholar 

Xavier MO, Poester VR, Trápaga MR, Stevens DA (2023) Sporothrix brasiliensis: epidemiology, therapy, and recent developments. J Fungi (Basel) 9(9):921. https://doi.org/10.3390/jof9090921

Article  CAS  PubMed  Google Scholar 

Portuondo DL, Batista-Duharte A, Ferreira LS et al (2016) A cell wall protein-based vaccine candidate induce protective immune response against Sporothrix schenckii infection. Immunobiology 221(2):300–309. https://doi.org/10.1016/j.imbio.2015.10.005

Article  CAS  PubMed  Google Scholar 

Della Terra PP, Rodrigues AM, Fernandes GF et al (2017) Exploring virulence and immunogenicity in the emerging pathogen Sporothrix brasiliensis. PLoS Negl Trop Dis 11(8):e0005903. https://doi.org/10.1371/journal.pntd.0005903

Article  CAS  PubMed  PubMed Central  Google Scholar 

Corrêa-Moreira D, Menezes RC, Romeo O et al (2021) Clinical and anatomopathological evaluation of BALB/c murine models infected with isolates of seven pathogenic Sporothrix species. Pathogens 10(12):1647. https://doi.org/10.3390/pathogens10121647

Article  CAS  PubMed  PubMed Central  Google Scholar 

Munhoz LS, Poester VR, Benelli JL et al (2023) Effectiveness of diphenyl diselenide against experimental Sporotrichosis caused by Sporothrix brasiliensis. Med Mycol. https://doi.org/10.1093/mmy/myad035

Article  PubMed  Google Scholar 

Sanchotene KO, Madrid IM, Klafke GB et al (2015) Sporothrix brasiliensis outbreaks and the rapid emergence of feline sporotrichosis. Mycoses. https://doi.org/10.1111/myc.12414

Article  PubMed  Google Scholar 

Fentener van Vlissingen JM, Borrens M, Girod A et al (2015) The reporting of clinical signs in laboratory animals: FELASA working group report. Lab Anim 49(4):267–283. https://doi.org/10.1177/0023677215584249

Article  CAS  PubMed  Google Scholar 

Poester VR, Munhoz LS, Nogueira CW et al (2021) Diphenyl diselenide alone and in combination with itraconazole against Sporothrix schenckii s.str. and Sporothrix globose. Braz J Microbiol 52(3):1271–1274. https://doi.org/10.1007/s42770-021-00506-2

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rabello VBS, de Melo TM, Meyer W et al (2023) Multi-locus sequencing typing reveals geographically related intraspecies variability of Sporothrix brasiliensis. Fungal Genet Biol 170:103845. https://doi.org/10.1016/j.fgb.2023.103845

Article  CAS  Google Scholar 

Falcão EMM, Romão AR, Magalhães MAFM et al (2022) A spatial analysis of the spread of hyperendemic sporotrichosis in the state of Rio de Janeiro. Brazil J Fungi 8(5):434. https://doi.org/10.3390/jof8050434

Article  Google Scholar 

Poester VR, Munhoz LS, Basso RP et al (2020) Disseminated sporotrichosis with immune reconstitution inflammatory syndrome in an HIV patient: case report and review of the literature. Rev Iberoam Micol. https://doi.org/10.1016/j.optmat.2011.11.002

Article  PubMed  Google Scholar 

Poester VR, Mattei AS, Madrid IM et al (2018) Sporotrichosis in Southern Brazil, towards an epidemic? Zoonoses Public Health. https://doi.org/10.1111/zph.12504

Article  PubMed  Google Scholar 

Morton DB (2000) A systematic approach for establishing humane endpoints. ILAR J 41(2):80–86. https://doi.org/10.1093/ilar.41.2.80

Article  CAS  PubMed  Google Scholar 

Hawkins P, Morton DB, Burman O et al (2011) A guide to defining and implementing protocols for the welfare assessment of laboratory animals: eleventh report of the BVAAWF/FRAME/RSPCA/UFAW joint working group on refinement. Lab Anim 45(1):1–13. https://doi.org/10.1258/la.2010.010031

Article  CAS  PubMed  Google Scholar 

Kanzler S, Rix A, Czigany Z et al (2016) Recommendation for severity assessment following liver resection and liver transplantation in rats: part I. Lab Anim 50(6):459–467. https://doi.org/10.1177/0023677216678018

Article  CAS  PubMed  Google Scholar 

Ullman-Cullere MH, Foltz CJ (1999) Body condition scoring: a rapid and accurate method for assessing health status in mice. Lab Animal Sci 49(3):319

CAS  Google Scholar 

Odds FC, Van Nuffel L, Gow NAR (2000) Survival in experimental Candida albicans infections depends on inoculum growth conditions as well as animal host. Microbiology (Reading) 146(8):1881–1889. https://doi.org/10.1099/00221287-146-8-1881

Article  CAS  PubMed  Google Scholar 

Langford DJ, Bailey AL, Chanda ML et al (2010) Coding of facial expressions of pain in the laboratory mouse. Nat Methods 7(6):447–449. https://doi.org/10.1038/nmeth.1455

Article  CAS  PubMed  Google Scholar 

Mei J, Banneke S, Lips J et al (2019) Refining humane endpoints in mouse models of disease by systematic review and machine learning-based endpoint definition. Altex 36(4):555–571. https://doi.org/10.14573/altex.1812231

Article  PubMed  Google Scholar 

Sass G, Larwood DJ, Martinez M et al (2021) Nikkomycin Z against disseminated coccidioidomycosis in a murine model of sustained release dosing. Antimicrob Agents Chemother 65(10):10–1128. https://doi.org/10.1128/AAC.00285-21

Article  Google Scholar 

Sass G, Larwood DJ, Martinez M et al (2021) Efficacy of nikkomycin Z in murine CNS coccidioidomycosis: modelling sustained-release dosing. J Antimicrob Chemother 76(10):2629–2635. https://doi.org/10.1093/jac/dkab223

Article  CAS  PubMed  Google Scholar 

留言 (0)

沒有登入
gif