Grant BF, Stinson FS, Dawson DA, Chou SP, Dufour MC, Compton W, Pickering RP, Kaplan K. Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the national epidemiologic survey on Alcohol and related conditions. Arch Gen Psychiatry. 2004;61(8):807–16.

Article  PubMed  Google Scholar 

Lotzin A, Grundmann J, Hiller P, Pawils S, Schafer I. Profiles of Childhood Trauma in Women with Substance Use disorders and Comorbid Posttraumatic stress disorders. Front Psychiatry. 2019;10:674.

Article  PubMed  PubMed Central  Google Scholar 

Hou L, Guo Y, Lian B, Wang Y, Li C, Wang G, Li Q, Pang J, Sun H, Sun L. Synaptic ultrastructure might be involved in HCN(1)-Related BDNF mRNA in withdrawal-anxiety after ethanol dependence. Front Psychiatry. 2018;9:215.

Article  PubMed  PubMed Central  Google Scholar 

Walker LC, Kastman HE, Krstew EV, Gundlach AL, Lawrence AJ. Central amygdala relaxin-3/relaxin family peptide receptor 3 signalling modulates alcohol seeking in rats. Br J Pharmacol. 2017;174(19):3359–69.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Abulseoud OA, Camsari UM, Ruby CL, Kasasbeh A, Choi S, Choi DS. Attenuation of ethanol withdrawal by ceftriaxone-induced upregulation of glutamate transporter EAAT2. Neuropsychopharmacology. 2014;39(7):1674–84.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wedekind D, Neumann K, Falkai P, Malchow B, Engel KR, Jamrozinski K, Havemann-Reinecke U. S100B and homocysteine in the acute alcohol withdrawal syndrome. Eur Arch Psychiatry Clin Neurosci. 2011;261(2):133–8.

Article  PubMed  Google Scholar 

Becker HC. Alcohol dependence, withdrawal, and relapse. Alcohol Res Health. 2008;31(4):348–61.

PubMed  PubMed Central  Google Scholar 

Liang J, Olsen RW. Alcohol use disorders and current pharmacological therapies: the role of GABA(A) receptors. Acta Pharmacol Sin. 2014;35(8):981–93.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Metten P, Crabbe JC. Alcohol withdrawal severity in inbred mouse (Mus musculus) strains. Behav Neurosci. 2005;119(4):911–25.

Article  PubMed  Google Scholar 

Tateno M, Saito T. Biological studies on alcohol-induced neuronal damage. Psychiatry Investig. 2008;5(1):21–7.

Article  PubMed  PubMed Central  Google Scholar 

N’Gouemo P, Morad M. Alcohol withdrawal is associated with a downregulation of large-conductance ca(2)(+)-activated K(+) channels in rat inferior colliculus neurons. Psychopharmacology. 2014;231(9):2009–18.

Article  PubMed  Google Scholar 

Nixon K, Crews FT. Binge ethanol exposure decreases neurogenesis in adult rat hippocampus. J Neurochem. 2002;83(5):1087–93.

Article  CAS  PubMed  Google Scholar 

Smith KR, Kopeikina KJ, Fawcett-Patel JM, Leaderbrand K, Gao R, Schurmann B, Myczek K, Radulovic J, Swanson GT, Penzes P. Psychiatric risk factor ANK3/ankyrin-G nanodomains regulate the structure and function of glutamatergic synapses. Neuron. 2014;84(2):399–415.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Deans PJM, Raval P, Sellers KJ, Gatford NJF, Halai S, Duarte RRR, Shum C, Warre-Cornish K, Kaplun VE, Cocks G, et al. Psychosis risk candidate ZNF804A localizes to synapses and regulates neurite formation and dendritic spine structure. Biol Psychiatry. 2017;82(1):49–61.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kloth K, Lozic B, Tagoe J, Hoffer MJV, Van der Ven A, Thiele H, Altmuller J, Kubisch C, Au PYB, Denecke J, et al. ANK3 related neurodevelopmental disorders: expanding the spectrum of heterozygous loss-of-function variants. Neurogenetics. 2021;22(4):263–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang CY, Rasband MN. Axon initial segments: structure, function, and disease. Ann N Y Acad Sci. 2018;1420(1):46–61.

Article  PubMed  PubMed Central  Google Scholar 

Peters LL, John KM, Lu FM, Eicher EM, Higgins A, Yialamas M, Turtzo LC, Otsuka AJ, Lux SE. Ank3 (epithelial ankyrin), a widely distributed new member of the ankyrin gene family and the major ankyrin in kidney, is expressed in alternatively spliced forms, including forms that lack the repeat domain. J Cell Biol. 1995;130(2):313–30.

Article  CAS  PubMed  Google Scholar 

Roby Y. ANK3 gene polymorphisms and bipolar disorder: a meta-analysis. Psychiatr Genet. 2017;27(6):225–35.

Article  CAS  PubMed  Google Scholar 

Athanasiu L, Mattingsdal M, Kahler AK, Brown A, Gustafsson O, Agartz I, Giegling I, Muglia P, Cichon S, Rietschel M, et al. Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort. J Psychiatr Res. 2010;44(12):748–53.

Article  PubMed  PubMed Central  Google Scholar 

Bi C, Wu J, Jiang T, Liu Q, Cai W, Yu P, Cai T, Zhao M, Jiang YH, Sun ZS. Mutations of ANK3 identified by exome sequencing are associated with autism susceptibility. Hum Mutat. 2012;33(12):1635–8.

Article  CAS  PubMed  Google Scholar 

Linke J, Witt SH, King AV, Nieratschker V, Poupon C, Gass A, Hennerici MG, Rietschel M, Wessa M. Genome-wide supported risk variant for bipolar disorder alters anatomical connectivity in the human brain. NeuroImage. 2012;59(4):3288–96.

Article  PubMed  Google Scholar 

Castaneda F, Rosin-Steiner S, Jung K. Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes. Int J Med Sci. 2006;4(1):28–35.

PubMed  PubMed Central  Google Scholar 

O’Donovan MC, Craddock N, Norton N, Williams H, Peirce T, Moskvina V, Nikolov I, Hamshere M, Carroll L, Georgieva L, et al. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet. 2008;40(9):1053–5.

Article  PubMed  Google Scholar 

Zhou Y, Dong F, Lanz TA, Reinhart V, Li M, Liu L, Zou J, Xi HS, Mao Y. Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment. Mol Psychiatry. 2018;23(4):952–62.

Article  CAS  PubMed  Google Scholar 

Hill MJ, Jeffries AR, Dobson RJ, Price J, Bray NJ. Knockdown of the psychosis susceptibility gene ZNF804A alters expression of genes involved in cell adhesion. Hum Mol Genet. 2012;21(5):1018–24.

Article  CAS  PubMed  Google Scholar 

Steinberg S, Mors O, Borglum AD, Gustafsson O, Werge T, Mortensen PB, Andreassen OA, Sigurdsson E, Thorgeirsson TE, Bottcher Y, et al. Expanding the range of ZNF804A variants conferring risk of psychosis. Mol Psychiatry. 2011;16(1):59–66.

Article  CAS  PubMed  Google Scholar 

Esslinger C, Kirsch P, Haddad L, Mier D, Sauer C, Erk S, Schnell K, Arnold C, Witt SH, Rietschel M, et al. Cognitive state and connectivity effects of the genome-wide significant psychosis variant in ZNF804A. NeuroImage. 2011;54(3):2514–23.

Article  PubMed  Google Scholar 

Zhang X, Sun H, Wang F, Niculescu M, Shen G, Zhou S, Yang F, Chen YH, Chen L, Wang W, et al. The Interaction between genetic variant ZNF804A rs1344706 and Alcohol Withdrawal on Impulsivity: evidence for the diathesis-stress model. Front Psychiatry. 2021;12:761237.

Article  PubMed  Google Scholar 

Calabro M, Mandelli L, Crisafulli C, Nicola MD, Colombo R, Janiri L, Lee SJ, Jun TY, Wang SM, Masand PS, et al. ZNF804A gene variants have a cross-diagnostic influence on psychosis and treatment improvement in Mood disorders. Clin Psychopharmacol Neurosci. 2020;18(2):231–40.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun Y, Zhao LY, Wang GB, Yue WH, He Y, Shu N, Lin QX, Wang F, Li JL, Chen N, et al. ZNF804A variants confer risk for heroin addiction and affect decision making and gray matter volume in heroin abusers. Addict Biol. 2016;21(3):657–66.

Article  CAS  PubMed  Google Scholar 

Nestor PG, O’Donovan K, Lapp HE, Hasler VC, Boodai SB, Hunter R. Risk and protective effects of serotonin and BDNF genes on stress-related adult psychiatric symptoms. Neurobiol Stress. 2019;11:100186.

Article  PubMed  PubMed Central  Google Scholar 

Liu J, Dai Q, Li W, Guo Y, Dai A, Wang Y, Deng M, Tang Z, She L, Chen X, et al. Association of vitamin D receptor gene polymorphisms with gestational diabetes mellitus-a case control study in Wuhan, China. BMC Pregnancy Childbirth. 2021;21(1):142.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shen G, Yang S, Wu L, Chen Y, Hu Y, Zhou F, Wang W, Liu P, Wu F, Liu Y, et al. The oxytocin receptor rs2254298 polymorphism and alcohol withdrawal symptoms: a gene-environment interaction in mood disorders. Front Psychiatry. 2023;14:1085429.

Article  PubMed  PubMed Central  Google Scholar 

Khemiri L, Brynte C, Konstenius M, Guterstam J, Rosendahl I, Franck J, Jayaram-Lindstrom N. Self-rated impulsivity in healthy individuals, substance use disorder and ADHD: psychometric properties of the Swedish barratt impulsiveness scale. BMC Psychiatry. 2021;21(1):458.

Article  CAS  PubMed  PubMed Central