Feasibility of intranasal human milk as stem cell therapy in preterm infants with intraventricular hemorrhage

Mukerji A, Shah V, Shah PS. Periventricular/intraventricular hemorrhage and neurodevelopmental outcomes: a meta-analysis. Pediatrics. 2015;136:1132–43.

Article  PubMed  Google Scholar 

Ahn SY, Chang YS, Park WS. Mesenchymal stem cells transplantation for neuroprotection in preterm infants with severe intraventricular hemorrhage. Korean J Pediatr. 2014;57:251–6.

Article  PubMed  PubMed Central  Google Scholar 

Briere C, McGrath J, Jensen T, Matson A, Finck C. Breast milk stem cells: current science and implications for preterm infants. Adv Neonatal Care. 2016;16:410–9.

Article  PubMed  Google Scholar 

Cotten CM, Murtha AP, Goldberg RN, Grotegut CA, Smith PB, Goldstein RF, et al. Feasibility of autologous cord blood cells for infants with hypoxic-ischemic encephalopathy. J Pediatr. 2014;164:973–979.e1.

Article  PubMed  Google Scholar 

Mitsialis SA, Kourembanas S. Stem cell–based therapies for the newborn lung and brain: possibilities and challenges. Semin Perinatol. 2015;40:138–51.

Article  Google Scholar 

Mukai T, Mori Y, Shimazu T, Takahashi A, Tsunoda H, Yamaguchi S, et al. Intravenous injection of umbilical cord-derived mesenchymal stromal cells attenuates reactive gliosis and hypomyelination in a neonatal intraventricular hemorrhage model. Neuroscience. 2017;355:175–87.

Article  CAS  PubMed  Google Scholar 

Park WS, Ahn SY, Sung SI, Ahn J, Chang YS. Mesenchymal stem cells: the magic cure for intraventricular hemorrhage? Cell Transpl. 2017;26:439–48.

Article  Google Scholar 

Twigger A, Hodgetts S, Filgueira L, Hartmann PE, Hassiotou F. From breast milk to brains. J Hum Lact. 2013;29:136–9.

Article  PubMed  Google Scholar 

Nabetani M, Shintaku H, Hamazaki T. Future perspectives of cell therapy for neonatal hypoxic–ischemic encephalopathy. Pediatr Res. 2018;83:356–63.

Article  CAS  PubMed  Google Scholar 

Hosseini SM, Talaei-Khozani T, Sani M, Owrangi B. Differentiation of human breast-milk stem cells to neural stem cells and neurons. Neurol Res Int. 2014;2014:807896–8.

Article  PubMed  PubMed Central  Google Scholar 

Keller T, Wengenroth L, Smorra D, Probst K, Kurian L, Kribs A, et al. Novel DRAQ5™/SYTOX® blue based flow cytometric strategy to identify and characterize stem cells in human breast milk. Cytom B Clin Cytom. 2019;96:480–9.

Article  CAS  Google Scholar 

Hassiotou F, Geddes DT, Hartmann PE. Cells in human milk. J Hum Lact. 2013;29:171–82.

Article  PubMed  Google Scholar 

Aydin MS, Yigit EN, Vatandaslar E, Erdogan E, Ozturk G. Transfer and integration of breast milk stem cells to the brain of suckling pups. Sci Rep. 2018;8:14289–9.

Article  PubMed  PubMed Central  Google Scholar 

Kersin SG, Özek E. Breast milk stem cells: are they magic bullets in neonatology? Turk Arch Pediatr. 2021;56:187–91.

Article  PubMed  PubMed Central  Google Scholar 

Keller T, Körber F, Oberthuer A, Schafmeyer L, Mehler K, Kuhr K, et al. Intranasal breast milk for premature infants with severe intraventricular hemorrhage—an observation. Eur J Pediatr. 2019;178:199–206

Article  CAS  PubMed  Google Scholar 

Li Y, Wu H, Jiang X, Dong Y, Zheng J, Gao J. New idea to promote the clinical applications of stem cells or their extracellular vesicles in central nervous system disorders: Combining with intranasal delivery. Acta Pharm Sin B. 2022;12:3215–32.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Herman S, Fishel I, Offen D. Intranasal delivery of mesenchymal stem cells‐derived extracellular vesicles for the treatment of neurological diseases. Stem Cells. 2021;39:1589–1600.

Article  PubMed  Google Scholar 

Borhani-Haghighi M, Navid S, Mohamadi Y. The therapeutic potential of conditioned medium from human breast milk stem cells in treating spinal cord injury. Asian Spine J. 2020;14:131–8.

Article  PubMed  Google Scholar 

Ballard O, Morrow AL. Human milk composition: nutrients and bioactive factors. Pediatr Clin North Am. 2013;60:49–74.

Article  PubMed  PubMed Central  Google Scholar 

Papile LA, Burstein J, Burstein R, Koffler H. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr. 1978;92:529–34.

Article  CAS  PubMed  Google Scholar 

Hassiotou F, Hartmann PE. At the dawn of a new discovery: the potential of breast milk stem cells. Adv Nutr. 2014;5:770–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

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