Breast cancer risks in older BRCA2 pathogenic variant carriers are understudied. Recent studies show a marked decline in the relative risk at older ages. We used data from two large studies to update the breast cancer risks in the BOADICEA model for BRCA2 carriers 60 years and older.
Competing Interest StatementL.F., D.F.E. and A.C.A. are listed as creators of the BOADICEA model, which has been licensed by Cambridge Enterprise (University of Cambridge)
Funding StatementThis work was supported by Cancer Research UK grant: PPRPGM-Nov20\100002
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Data AvailabilityAll data produced in the present work are contained in the manuscript (or referenced literature)
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