CA19-9 producing locally advanced papillary thyroid carcinoma: a case report

Indellicato R, Zulueta A, Caretti A, Trinchera M. Complementary use of carbohydrate antigens Lewis a, Lewis b, and Sialyl-Lewis a (CA19.9 epitope) in gastrointestinal cancers: biological rationale towards a personalized clinical application. Cancers. 2020;12:1509.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Megwalu UC, Moon PK. Thyroid cancer incidence and mortality trends in the United States: 2000–2018. Thyroid. 2022;32:560–70.

Article  CAS  PubMed  Google Scholar 

Netzel BC, Grebe SK, Carranza Leon BG, Castro MR, Clark PM, Hoofnagle AN, et al. Thyroglobulin (Tg) testing revisited: Tg assays, TgAb assays, and correlation of results with clinical outcomes. J Clin Endocrinol Metab. 2015;100:E1074–83.

Article  PubMed  PubMed Central  Google Scholar 

Spencer C, Petrovic I, Fatemi S, LoPresti J. Serum thyroglobulin (Tg) monitoring of patients with differentiated thyroid cancer using sensitive (second-generation) immunometric assays can be disrupted by false-negative and false-positive serum thyroglobulin autoantibody misclassifications. J Clin Endocrinol Metab. 2014;99:4589–99.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Herlyn M, Steplewski Z, Herlyn D, Koprowski H. Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies. Proc Natl Acad Sci USA. 1979;76:1438–42.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Luo G, Jin K, Deng S, Cheng H, Fan Z, Gong Y, et al. Roles of CA19-9 in pancreatic cancer: biomarker, predictor and promoter. Biochim Biophys Acta Rev Cancer. 2021;1875: 188409.

Article  CAS  PubMed  Google Scholar 

Hattrup CL, Gendler SJ. Structure and function of the cell surface (tethered) mucins. Annu Rev Physiol. 2008;70:431–57.

Article  CAS  PubMed  Google Scholar 

Goonetilleke KS, Siriwardena AK. Systematic review of carbohydrate antigen (CA 19-9) as a biochemical marker in the diagnosis of pancreatic cancer. Eur J Surg Oncol. 2007;33:266–70.

Article  CAS  PubMed  Google Scholar 

Patel AH, Harnois DM, Klee GG, LaRusso NF, Gores GJ. The utility of CA 19-9 in the diagnoses of cholangiocarcinoma in patients without primary sclerosing cholangitis. Am J Gastroenterol. 2000;95:204–7.

Article  CAS  PubMed  Google Scholar 

Duffy MJ, van Dalen A, Haglund C, Hansson L, Klapdor R, Lamerz R, et al. Clinical utility of biochemical markers in colorectal cancer: European Group on Tumour Markers (EGTM) guidelines. Eur J Cancer. 2003;39:718–27.

Article  CAS  PubMed  Google Scholar 

Gadducci A, Cosio S, Carpi A, Nicolini A, Genazzani AR. Serum tumor markers in the management of ovarian, endometrial and cervical cancer. Biomed Pharmacother. 2004;58:24–38.

Article  CAS  PubMed  Google Scholar 

Larena A, Vierbuchen M, Fischer R. Blood group antigen expression in malignant tumors of the thyroid: a parallel between medullary and nonmedullary carcinomas. Langenbecks Arch Chir. 1995;380:269–72.

Article  CAS  PubMed  Google Scholar 

Alencar R, Kendler DB, Andrade F, Nava C, Bulzico D, Cordeiro de Noronha Pessoa C, et al. CA19-9 as a predictor of worse clinical outcome in medullary thyroid carcinoma. Eur Thyroid J. 2019;8:186–91.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Elisei R, Lorusso L, Piaggi P, Torregrossa L, Pellegrini G, Molinaro E, et al. Elevated level of serum carbohydrate antigen 19.9 as predictor of mortality in patients with advanced medullary thyroid cancer. Eur J Endocrinol. 2015;173:297–304.

Article  CAS  PubMed  Google Scholar 

Lorusso L, Romei C, Piaggi P, Fustini C, Molinaro E, Agate L, et al. Ca19.9 positivity and doubling time are prognostic factors of mortality in patients with advanced medullary thyroid cancer with no evidence of structural disease progression according to response evaluation criteria in solid tumors. Thyroid. 2021;31:1050–5.

Article  CAS  PubMed  Google Scholar 

Hashimoto T, Matsubara F, Mizukami Y, Miyazaki I, Michigishi T, Yanaihara N. Tumor markers and oncogene expression in thyroid cancer using biochemical and immunohistochemical studies. Endocrinol Jpn. 1990;37:247–54.

Article  CAS  PubMed  Google Scholar 

Vierbuchen M, Schröder S, Uhlenbruck G, Ortmann M, Fischer R. CA 50 and CA 19-9 antigen expression in normal, hyperplastic, and neoplastic thyroid tissue. Lab Invest. 1989;60:726–32.

CAS  PubMed  Google Scholar 

Kihara M, Miyauchi A, Hirokawa M, Fujishima M, Masuoka H, Higashiyama T, et al. Metastatic papillary thyroid carcinoma presenting with elevated serum levels of carbohydrate antigen 19-9 (CA19-9): a case report. Surg Case Rep. 2022;8:45.

Article  PubMed  PubMed Central  Google Scholar 

Yamaguchi E, Makino Y, Sato T, Uchida M, Harada Y, Maruyama R. CA19-9-producing lung metastasis after surgery for papillary thyroid carcinoma: report of a case. Surg Today. 2014;44:2157–61.

Article  PubMed  PubMed Central  Google Scholar 

Duffy MJ, Evoy D, McDermott EW. CA 15-3: uses and limitation as a biomarker for breast cancer. Clin Chim Acta. 2010;411:1869–74.

Article  CAS  PubMed  Google Scholar 

Renaud F, Gnemmi V, Devos P, Aubert S, Crépin M, Coppin L, et al. MUC1 expression in papillary thyroid carcinoma is associated with BRAF mutation and lymph node metastasis; the latter is the most important risk factor of relapse. Thyroid. 2014;24:1375–84.

Article  CAS  PubMed  Google Scholar 

Siragusa M, Zerilli M, Iovino F, Francipane MG, Lombardo Y, Ricci-Vitiani L, et al. MUC1 oncoprotein promotes refractoriness to chemotherapy in thyroid cancer cells. Cancer Res. 2007;67:5522–30.

Article  CAS  PubMed  Google Scholar 

Cazet A, Julien S, Bobowski M, Burchell J, Delannoy P. Tumour-associated carbohydrate antigens in breast cancer. Breast Cancer Res. 2010;12:204.

Article  PubMed  PubMed Central  Google Scholar 

Fritz S, Hackert T, Hinz U, Hartwig W, Büchler MW, Werner J. Role of serum carbohydrate antigen 19-9 and carcinoembryonic antigen in distinguishing between benign and invasive intraductal papillary mucinous neoplasm of the pancreas. Br J Surg. 2011;98:104–10.

Article  CAS  PubMed  Google Scholar 

Lee T, Teng TZJ, Shelat VG. Carbohydrate antigen 19-9—tumor marker: past, present, and future. World J Gastrointest Surg. 2020;12:468–90.

Article  PubMed  PubMed Central  Google Scholar 

Mochizuki Y, Ito K, Izumi H, Kohno K, Amano J. Expression of polypeptide N-acetylgalactosaminyl transferase-3 and its association with clinicopathological factors in thyroid carcinomas. Thyroid. 2013;23:1553–60.

Article  CAS  PubMed  Google Scholar 

Ogawa M, Hori H, Hirayama M, Kobayashi M, Shiraishi T, Watanabe Y, et al. Anaplastic transformation from papillary thyroid carcinoma with increased serum CA19-9. Pediatr Blood Cancer. 2005;45:64–7.

Article  PubMed  Google Scholar 

留言 (0)

沒有登入
gif