The impact of a second embryo biopsy for preimplantation genetic testing for monogenic diseases (PGT-M) with inconclusive results on pregnancy potential: results from a matched case–control study

ESHRE PGT Consortium and SIG-Embryology Biopsy Working Group, Kokkali G, Coticchio G, Bronet F, Celebi C, Cimadomo D, Goossens V, Liss J, Nunes S, Sfontouris I, Vermeulen N, Zakharova E, De Rycke M. ESHRE PGT Consortium and SIG Embryology good practice recommendations for polar body and embryo biopsy for PGT. Hum Reprod Open. 2020;2020(3):hoaa020. https://doi.org/10.1093/hropen/hoaa020.

Article  PubMed Central  Google Scholar 

Coll L, Parriego M, Boada M, Devesa M, Arroyo G, Rodríguez I, Coroleu B, Vidal F, Veiga A. Transition from blastomere to trophectoderm biopsy: comparing two preimplantation genetic testing for aneuploidies strategies. Zygote. 2018;26(3):191–8. https://doi.org/10.1017/S0967199418000084.

Article  CAS  PubMed  Google Scholar 

Scott RT Jr, Ferry K, Su J, Tao X, Scott K, Treff NR. Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study. Fertil Steril. 2012;97(4):870–5. https://doi.org/10.1016/j.fertnstert.2012.01.104.

Article  PubMed  Google Scholar 

Scott RT Jr, Upham KM, Forman EJ, Hong KH, Scott KL, Taylor D, Tao X, Treff NR. Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery rates: a randomized controlled trial. Fertil Steril. 2013;100(3):697–703. https://doi.org/10.1016/j.fertnstert.2013.04.035.

Article  PubMed  Google Scholar 

Scott RT Jr, Upham KM, Forman EJ, Zhao T, Treff NR. Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial. Fertil Steril. 2013;100(3):624–30. https://doi.org/10.1016/j.fertnstert.2013.04.039.

Article  PubMed  Google Scholar 

Capalbo A, Ubaldi FM, Cimadomo D, Maggiulli R, Patassini C, Dusi L, Sanges F, Buffo L, Venturella R, Rienzi L. Consistent and reproducible outcomes of blastocyst biopsy and aneuploidy screening across different biopsy practitioners: a multicentre study involving 2586 embryo biopsies. Hum Reprod. 2016;31(1):199–208. https://doi.org/10.1093/humrep/dev294.

Article  PubMed  Google Scholar 

Cimadomo D, Capalbo A, Ubaldi FM, Scarica C, Palagiano A, Canipari R, Rienzi L. The impact of biopsy on human embryo developmental potential during preimplantation genetic diagnosis. Biomed Res Int. 2016;2016:7193075. https://doi.org/10.1155/2016/7193075.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Coonen E, van Montfoort A, Carvalho F, Kokkali G, Moutou C, Rubio C, De Rycke M, Goossens V. ESHRE PGT Consortium data collection XVI-XVIII: cycles from 2013 to 2015. Hum Reprod Open. 2020;2020(4):hoaa043. https://doi.org/10.1093/hropen/hoaa043.

Article  CAS  PubMed  PubMed Central  Google Scholar 

De Rycke M, Belva F, Goossens V, Moutou C, SenGupta SB, Traeger-Synodinos J, Coonen E. ESHRE PGD Consortium data collection XIII: cycles from January to December 2010 with pregnancy follow-up to October 2011. Hum Reprod. 2015;30(8):1763–89. https://doi.org/10.1093/humrep/dev122.

Article  PubMed  Google Scholar 

Cimadomo D, Rienzi L, Romanelli V, Alviggi E, Levi-Setti PE, Albani E, Dusi L, Papini L, Livi C, Benini F, Smeraldi A, Patassini C, Ubaldi FM, Capalbo A. Inconclusive chromosomal assessment after blastocyst biopsy: prevalence, causative factors and outcomes after re-biopsy and re-vitrification. A multicenter experience. Hum Reprod. 2018;33(10):1839–46. https://doi.org/10.1093/humrep/dey282.

Article  PubMed  Google Scholar 

Neal SA, Sun L, Jalas C, Morin SJ, Molinaro TA, Scott RT Jr. When next-generation sequencing-based preimplantation genetic testing for aneuploidy (PGT-A) yields an inconclusive report: diagnostic results and clinical outcomes after re biopsy. J Assist Reprod Genet. 2019;36(10):2103–9. https://doi.org/10.1007/s10815-019-01550-6.

Article  PubMed  PubMed Central  Google Scholar 

Neitzel D, Alouf CA, Robinson K, Zhu M, Faulkner N. Re-biopsied PGS embryos yield actionable results. Fertil Steril. 2017;108(3):e290. https://doi.org/10.1016/j.fertnstert.2017.07.857.

Article  Google Scholar 

Greco E, Biricik A, Cotarelo RP, Iammarone E, Rubino P, Tesarik J, Fiorentino F, Minasi MG. Successful implantation and live birth of a healthy boy after triple biopsy and double vitrification of oocyte-embryo-blastocyst. Springerplus. 2015;14(4):22. https://doi.org/10.1186/s40064-015-0788-y.

Article  Google Scholar 

Bradley CK, Livingstone M, Traversa MV, McArthur SJ. Impact of multiple blastocyst biopsy and vitrification-warming procedures on pregnancy outcomes. Fertil Steril. 2017;108(6):999–1006. https://doi.org/10.1016/j.fertnstert.2017.09.013.

Article  PubMed  Google Scholar 

Zimmerman RS, Jalas C, Tao X, Fedick AM, Kim JG, Pepe RJ, Northrop LE, Scott RT Jr, Treff NR. Development and validation of concurrent preimplantation genetic diagnosis for single gene disorders and comprehensive chromosomal aneuploidy screening without whole genome amplification. Fertil Steril. 2016;105(2):286–94. https://doi.org/10.1016/j.fertnstert.2015.10.003.

Article  CAS  PubMed  Google Scholar 

Ciaffaglione M, Reschini M, Balli M, Guarneri C, Palermo MC, Pinna M, Pisaturo V, Somigliana E, Paffoni A, Vigano’ P. Post-thaw day 5 blastocyst culture time prior to transfer does not affect assisted reproduction technology (ART) outcomes in frozen-thawed embryo transfer cycles. J Clin Med. 2022;11(24):7444. https://doi.org/10.3390/jcm11247444.PMID:36556058.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Somigliana E, Sarais V, Reschini M, Ferrari S, Makieva S, Cermisoni GC, Paffoni A, Papaleo E, Vigano P. Single oral dose of vitamin D3 supplementation prior to in vitro fertilization and embryo transfer in normal weight women: the SUNDRO randomized controlled trial. Am J Obstet Gynecol. 2021;225(3):283.e1-283.e10. https://doi.org/10.1016/j.ajog.2021.04.234.

Article  CAS  PubMed  Google Scholar 

Alteri A, Cermisoni GC, Pozzoni M, Gaeta G, Cavoretto PI, Viganò P. Obstetric, neonatal, and child health outcomes following embryo biopsy for preimplantation genetic testing. Hum Reprod Update. 2023;29(3):291–306. https://doi.org/10.1093/humupd/dmad001.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Giacomini E, Pagliardini L, Minetto S, Pinna M, Kleeman F, Bonesi F, Makieva S, Pavone V, Reschini M, Papaleo E, Candiani M, Somigliana E, Viganò P. The relationship between CYP19A1 gene expression in luteinized granulosa cells and follicular estradiol output in women with endometriosis. J Steroid Biochem Mol Biol. 2024;237:106439. https://doi.org/10.1016/j.jsbmb.2023.106439.

Article  CAS  PubMed  Google Scholar 

Casalechi M, Di Stefano G, Fornelli G, Somigliana E, Viganò P. Impact of endometriosis on the ovarian follicles. Best Pract Res Clin Obstet Gynaecol. 2024;92:102430. https://doi.org/10.1016/j.bpobgyn.2023.102430.

Article  PubMed  Google Scholar 

Palomba S, Viganò P, Chamayou S, Donarelli Z, Costantini MP, Marci R, Piomboni P, Fino E, Montano L, Guglielmino A, Somigliana E, and the SIRU Working Group on Italian Guideline for Infertility. Diagnosis and management of infertility: NICE-adapted guidelines from the Italian Society of Human Reproduction. Reprod Biol Endocrinol. 2024;22(1):9. https://doi.org/10.1186/s12958-023-01179-2.

Article  PubMed  PubMed Central  Google Scholar 

Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology. The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. Hum Reprod. 2011;26(6):1270–83. https://doi.org/10.1093/humrep/der037.

Article  Google Scholar 

Nohales M, Coello A, Martin A, Insua F, Meseguer M, de Los Santos MJ. Should embryo rebiopsy be considered a regular strategy to increase the number of embryos available for transfer? J Assist Reprod Genet. 2023;40(8):1905–13. https://doi.org/10.1007/s10815-023-02875-z.

Article  PubMed  Google Scholar 

Giuliano R, Maione A, Vallefuoco A, Sorrentino U, Zuccarello D. Preimplantation genetic testing for genetic diseases: limits and review of current literature. Genes (Basel). 2023;14(11):2095. https://doi.org/10.3390/genes14112095.

Article  CAS  PubMed  Google Scholar 

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