S. Melmed, Pathogenesis and diagnosis of growth hormone deficiency in adults. N. Engl. J. Med. 380(26), 2551–2562 (2019)
N.A. Tritos, B.M.K. Biller, Current concepts of the diagnosis of adult growth hormone deficiency. Rev. Endocr. Metab. Disord. 22(1), 109–116 (2021)
C.C. van Bunderen, D.S. Olsson, Growth hormone deficiency and replacement therapy in adults: impact on survival. Rev. Endocr. Metab. Disord. 22(1), 125–133 (2021)
M.E. Molitch, D.R. Clemmons, S. Malozowski, G.R. Merriam, M. Lee Vance; Endocrine Society, Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society clinical practice guideline. J. Clin. Endocrinol. Metab. 96(6), 1587–1609 (2011)
N.A. Tritos, B.M.K. Biller, Growth hormone and bone. Curr. Opin. Endocrinol. Diabetes Obes. 16(6), 415–422 (2009)
P.S. Dixit M, S. Yakar, Effects of GH/IGF axis on bone and cartilage. Mol. Cell Endocrinol. 519, 111052 (2021)
H.L. Racine, M.A. Serrat, The actions of IGF-1 in the growth plate and its role in postnatal bone elongation. Curr. Osteoporos. Rep. 18(3), 210–227 (2020)
PubMed PubMed Central Google Scholar
S.J. Holmes, S.M. Shalet, Role of growth hormone and sex steroids in achieving and maintaining normal bone mass. Horm. Res. 45(1–2), 86–93 (1996)
J.S. Walsh, Y. Henry, D. Fatayerji, R. Eastell, Hormonal determinants of bone turnover before and after attainment of peak bone mass. Clin. Endocrinol. 72(3), 320–327 (2010)
Q. Wang, E. Seeman, Skeletal growth and peak bone strength. Best Pract. Res. Clin. Endocrinol. Metab. 22(5), 687–700 (2008)
S. Zhang, Y. Cui, X. Ma, J. Yong, L. Yan, M. Yang, J. Ren, F. Tang, L. Wen, J. Qiao, Single-cell transcriptomics identifies divergent developmental lineage trajectories during human pituitary development. Nat. Commun. 11(1), 5275 (2020)
CAS PubMed PubMed Central Google Scholar
M. Gangat, S. Radovick, Pitutary hypoplasia. Endocrinol. Metab. Clin. N. Am. 46(2), 247–257 (2017)
J.J. Díez, S. Sangiao-Alvarellos, F. Cordido, Treatment with growth hormone for adults with growth hormone deficiency syndrome: benefits and risks. Int J. Mol. Sci. 19(3), 893 (2018)
PubMed PubMed Central Google Scholar
H. Yang, K. Yan, X. Yuping, Q. Zhang, L. Wang, F. Gong, H. Zhu, W. Xia, H. Pan, Bone microarchitecture and volumetric bone density impairment in young male adults with childhood-onset growth hormone deficiency. Eur. J. Endocrinol. 180(2), 145–153 (2019)
S. Liu et al. Reduced bone mineral density in middle-aged male patients with adult growth hormone deficiency. Horm. Metab. Res. 54(7), 450–457 (2022)
H. Zhu, Y. Xu, F. Gong, G. Shan, H. Yang, K. Xu, D. Zhang, X. Cheng, Z. Zhang, S. Chen, L. Wang, H. Pan, Reference ranges for serum insulin-like growth factor I (IGF-I) in healthy Chinese adults. PLoS ONE 12(10), e0185561 (2017)
PubMed PubMed Central Google Scholar
H. Li, C.-Y. Ji, X.-N. Zong, Y.-Q. Zhang, Height and weight standardized growth charts for Chinese children and adolescents aged 0 to 18 years. Zhonghua Er Ke Za Zhi 47(7), 487–492 (2009)
A. Giustina, G. Mazziotti, E. Canalis, Growth hormone, insulin-like growth factors, and the skeleton. Endocr. Rev. 29(5), 535–559 (2008)
CAS PubMed PubMed Central Google Scholar
S. Yakar, H. Werner, C.J. Rosen, Insulin-like growth factors: actions on the skeleton. J. Mol. Endocrinol. 61(1), T115–T137 (2018)
CAS PubMed PubMed Central Google Scholar
J. Banu, L. Wang, D.N. Kalu, Effects of increased muscle mass on bone in male mice overexpressing IGF-I in skeletal muscles. Calcif. Tissue Int. 73(2), 196–201 (2003)
L. Xu et al. Concerted actions of insulin-like growth factor 1, testosterone, and estradiol on peripubertal bone growth: a 7-year longitudinal study. J. Bone Min. Res. 26(9), 2204–2211 (2011)
M.E. Breen et al. 25-hydroxyvitamin D, insulin-like growth factor-I, and bone mineral accrual during growth. J. Clin. Endocrinol. Metab. 96(1), E89–E98 (2011)
R. Bouillon et al. Bone status and fracture prevalence in Russian adults with childhood-onset growth hormone deficiency. J. Clin. Endocrinol. Metab. 89(10), 4993–4998 (2004)
T. Rosén, T. Hansson, H. Granhed, J. Szucs, B.A. Bengtsson, Reduced bone mineral content in adult patients with growth hormone deficiency. Acta Endocrinol. 129(3), 201–206 (1993)
P.V. Carroll et al. Growth hormone deficiency in adulthood and the effects of growth hormone replacement: a review. Growth Hormone Research Society Scientific Committee. J. Clin. Endocrinol. Metab. 83(2), 382–395 (1998)
J.M. Kaufman, P. Taelman, A. Vermeulen, M. Vandeweghe, Bone mineral status in growth hormone-deficient males with isolated and multiple pituitary deficiencies of childhood onset. J. Clin. Endocrinol. Metab. 74(1), 118–123 (1992)
S. Cvijetić, M. Korsić, Apparent bone mineral density estimated from DXA in healthy men and women. Osteoporos. Int. 15(4), 295–300 (2004)
N.M. Appelman-Dijkstra et al. Effects of up to 15 years of recombinant human GH (rhGH) replacement on bone metabolism in adults with growth hormone deficiency (GHD): the Leiden Cohort Study. Clin. Endocrinol. 81(5), 727–735 (2014)
N.M. Appelman-Dijkstra et al. Long-term effects of recombinant human GH replacement in adults with GH deficiency: a systematic review. Eur. J. Endocrinol. 169(1), R1–R14 (2013)
W.M. Drake et al. The influence of gender on the short and long-term effects of growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults: a 5-year study. Clin. Endocrinol. 54(4), 525–532 (2001)
G. Götherström et al. Ten-year GH replacement increases bone mineral density in hypopituitary patients with adult onset GH deficiency. Eur. J. Endocrinol. 156(1), 55–64 (2007)
M. Elbornsson et al. Fifteen years of GH replacement increases bone mineral density in hypopituitary patients with adult-onset GH deficiency. Eur. J. Endocrinol. 166(5), 787–795 (2012)
CAS PubMed PubMed Central Google Scholar
A.P. Delitala, A. Scuteri, C. Doria, Thyroid hormone diseases and osteoporosis. J. Clin. Med. 9(4), 1034 (2020)
CAS PubMed PubMed Central Google Scholar
D. Tuchendler, M. Bolanowski, The influence of thyroid dysfunction on bone metabolism. Thyroid Res. 7(1), 12 (2014)
PubMed PubMed Central Google Scholar
V. Birzniece, K.K.Y. Ho, Sex steroids and the GH axis: implications for the management of hypopituitarism. Best Pract. Res. Clin. Endocrinol. Metab. 31(1), 59–69 (2017)
J. Gibney et al. Growth hormone and testosterone interact positively to enhance protein and energy metabolism in hypopituitary men. Am. J. Physiol. Endocrinol. Metab. 289(2), E266–E271 (2005)
G. Götherström et al. A prospective study of 5 years of GH replacement therapy in GH-deficient adults: sustained effects on body composition, bone mass, and metabolic indices. J. Clin. Endocrinol. Metab. 86(10), 4657–4665 (2001)
A. Rossini et al. Bone and body composition analyses by DXA in adults with GH deficiency: effects of long-term replacement therapy. Endocrine 74(3), 666–675 (2021)
P. Kendall-Taylor et al. The clinical, metabolic and endocrine features and the quality of life in adults with childhood-onset craniopharyngioma compared with adult-onset craniopharyngioma. Eur. J. Endocrinol. 152(4), 557–567 (2005)
S.S. van Santen et al. Fractures, bone mineral density, and final height in craniopharyngioma patients with a follow-up of 16 years. J. Clin. Endocrinol. Metab. 105(4), e1397–e1407 (2020)
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