American Academy of Orthopaedic Surgeons Technology Overview Summary: Platelet-Rich Plasma (PRP) for Knee Osteoarthritis

Truman Medical Center, University of Missouri, Columbia, MO (Dubin), Departments of Orthopaedic Surgery and Cell Biology, New York University School of Medicine, NYU Langone Health, New York, NY (Leucht), Harvard Medical School, Boston Children's Hospital, Boston, MA (Murray), American Academy of Orthopaedic Surgeons, Rosemont, IL (Pezold).

Murray or an immediate family member has received royalties from the American Journal of Sports Medicine; serves as a paid consultant to Miach Orthopedics; has stock or stock options held in MIACH Orthopaedics, Inc; has received nonincome support (such as equipment or services), commercially derived honoraria, or other non-research–related funding (such as paid travel) from the American Journal of Sports Medicine, Springer, the Journal of Orthopaedic Research, and the Orthopaedic Journal of Sports Medicine: Editorial or governing board; Leucht or an immediate family member serves as a paid consultant to Ankasa Regenerative Therapeutics and Stryker; has stock or stock options held in Ankasa Regenerative Therapeutics; has received nonincome support (such as equipment or services), commercially derived honoraria, or other non-research–related funding (such as paid travel) from Springer; serves as a board member, owner, officer, or committee member of the Orthopaedic Trauma Association and the Journal of Orthopaedic Research: Editorial or governing board. Neither of the following authors nor any immediate family member has received anything of value from or has stock or stock options held in a commercial company or institution related directly or indirectly to the subject of this article: Dubin and Pezold,

This technology overview was approved by the American Academy of Orthopaedic Surgeons Board of Directors on June 20, 2022.

Work Group Members: Rachel Frank, MD, FAAOS, Michael A. Mont, MD, FAAOS, Arjun Saxena, MD, MBA, FAAOS, Samuel Young, MD, FAAOS, Rupesh Tarwala, MD, Jacob Calcei, MD, Giuseppe Filardo, MD, PhD, MBAQ.

Contributors: Zhongming Chen, MD, Oliver Sax, DO.

Staff of the American Academy of Orthopaedic Surgeons: Jayson Murray, MA, MBA, Anushree Tiwari, MPH, Nicole Nelson, MPH, Connor Riley, MPH, Tyler Verity, Jennifer Rodriguez, MBA.

The complete document, Technology Overview: Platelet-Rich Plasma (PRP) for Knee Osteoarthritis, includes all tables and figures and is available at https://www.aaos.org/quality/biologics/technology-overviews/

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