Simonneau G, Gatzoulis MA, Adatia I, Celermajer D, Denton C, Ghofrani A, et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol. 2013;62:D34–41.

Article  PubMed  Google Scholar 

Valerio L, Mavromanoli AC, Barco S, Abele C, Becker D, Bruch L, et al. Chronic thromboembolic pulmonary hypertension and impairment after pulmonary embolism: the FOCUS study. Eur Heart J. 2022;43:3387–98.

Article  PubMed  PubMed Central  Google Scholar 

Gall H, Hoeper MM, Richter MJ, Cacheris W, Hinzmann B, Mayer E. An epidemiological analysis of the burden of chronic thromboembolic pulmonary hypertension in the USA, Europe and Japan. Eur Respir Rev. 2017;26.

Simonneau G, Torbicki A, Dorfmuller P, Kim N. The pathophysiology of chronic thromboembolic pulmonary hypertension. Eur Respir Rev. 2017;26.

Galie N, Humbert M, Vachiery JL, Gibbs S, Lang I, Torbicki A, et al. 2015 ESC/ERS guidelines for the diagnosis and treatment of pulmonary hypertension: the Joint Task Force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). Eur Heart J. 2016;37:67–119.

Article  PubMed  Google Scholar 

Humbert M, Kovacs G, Hoeper MM, Badagliacca R, Berger RMF, Brida M, et al. 2022 ESC/ERS guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Heart J. 2022;43:3618–731.

Article  CAS  PubMed  Google Scholar 

Pepke-Zaba J, Delcroix M, Lang I, Mayer E, Jansa P, Ambroz D, et al. Chronic thromboembolic pulmonary hypertension (CTEPH): results from an international prospective registry. Circulation. 2011;124:1973–81.

Article  PubMed  Google Scholar 

Rotzinger DC, Rezaei-Kalantari K, Aubert JD, Qanadli SD. Pulmonary angioplasty: a step further in the continuously changing landscape of chronic thromboembolic pulmonary hypertension management. Eur J Radiol. 2021;136:109562.

Article  PubMed  Google Scholar 

Mahmud E, Madani MM, Kim NH, Poch D, Ang L, Behnamfar O, et al. Chronic thromboembolic pulmonary hypertension: evolving therapeutic approaches for operable and inoperable disease. J Am Coll Cardiol. 2018;71:2468–86.

Article  PubMed  Google Scholar 

Moradi F, Morris TA, Hoh CK. Perfusion scintigraphy in diagnosis and management of Thromboembolic Pulmonary Hypertension. Radiographics. 2019;39:169–85.

Article  PubMed  Google Scholar 

Bajc M, Schumichen C, Gruning T, Lindqvist A, Le Roux PY, Alatri A, et al. EANM guideline for ventilation/perfusion single-photon emission computed tomography (SPECT) for diagnosis of pulmonary embolism and beyond. Eur J Nucl Med Mol Imaging. 2019;46:2429–51.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Koike H, Sueyoshi E, Sakamoto I, Uetani M, Nakata T, Maemura K. Comparative clinical and predictive value of lung perfusion blood volume CT, lung perfusion SPECT and catheter pulmonary angiography images in patients with chronic thromboembolic pulmonary hypertension before and after balloon pulmonary angioplasty. Eur Radiol. 2018;28:5091–9.

Article  PubMed  Google Scholar 

Maruoka Y, Nagao M, Baba S, Isoda T, Kitamura Y, Yamazaki Y, et al. Three-dimensional fractal analysis of 99mTc-MAA SPECT images in chronic thromboembolic pulmonary hypertension for evaluation of response to balloon pulmonary angioplasty: association with pulmonary arterial pressure. Nucl Med Commun. 2017;38:480–6.

Article  PubMed  PubMed Central  Google Scholar 

Derlin T, Kelting C, Hueper K, Weiberg D, Meyer K, Olsson KM, et al. Quantitation of perfused lung volume using hybrid SPECT/CT allows Refining the Assessment of Lung Perfusion and estimating Disease Extent in Chronic Thromboembolic Pulmonary Hypertension. Clin Nucl Med. 2018;43:e170–7.

Article  PubMed  Google Scholar 

Hashimoto H, Oka T, Nakanishi R, Mizumura S, Dobashi S, Hashimoto Y, et al. Evaluation of balloon pulmonary angioplasty using lung perfusion SPECT in patients with chronic thromboembolic pulmonary hypertension. J Nucl Cardiol. 2022;29:3392–400.

Article  PubMed  PubMed Central  Google Scholar 

Ha S, Han S. The role of Lung Ventilation/Perfusion scan in the management of Chronic Thromboembolic Pulmonary Hypertension. Nucl Med Mol Imaging; 2023.

Oh DK, Song JM, Park DW, Oh SY, Ryu JS, Lee J, et al. The effect of a multidisciplinary team on the implementation rates of major diagnostic and therapeutic procedures of chronic thromboembolic pulmonary hypertension. Heart Lung. 2019;48:28–33.

Article  PubMed  Google Scholar 

Kang BJ, Lee SD, Oh YM, Lee JS. Improved survival of Korean patients with idiopathic pulmonary arterial hypertension after the introduction of targeted therapies. Heart Lung. 2014;43:561–8.

Article  PubMed  Google Scholar 

Leblanc M, Leveillee F, Turcotte E. Prospective evaluation of the negative predictive value of V/Q SPECT using 99mTc-Technegas. Nucl Med Commun. 2007;28:667–72.

Article  PubMed  Google Scholar 

Elf JE, Jogi J, Bajc M. Home treatment of patients with small to medium sized acute pulmonary embolism. J Thromb Thrombolysis. 2015;39:166–72.

Article  CAS  PubMed  Google Scholar 

Parker JA, Coleman RE, Grady E, Royal HD, Siegel BA, Stabin MG, et al. SNM practice guideline for lung scintigraphy 4.0. J Nucl Med Technol. 2012;40:57–65.

Article  PubMed  Google Scholar 

Skoro-Sajer N, Becherer A, Klepetko W, Kneussl MP, Maurer G, Lang IM. Longitudinal analysis of perfusion lung scintigrams of patients with unoperated chronic thromboembolic pulmonary hypertension. Thromb Haemost. 2004;92:201–7.

Article  CAS  PubMed  Google Scholar 

Dickson JC, Armstrong IS, Gabina PM, Denis-Bacelar AM, Krizsan AK, Gear JM, et al. EANM practice guideline for quantitative SPECT-CT. Eur J Nucl Med Mol Imaging. 2023;50:980–95.

Article  PubMed  Google Scholar 

Le Pennec R, Tromeur C, Orione C, Robin P, Le Mao R, Gut-Gobert C, et al. Quantification of the pulmonary vascular obstruction index on ventilation/perfusion lung scintigraphy: comparison of a segmental visual scoring to the Meyer score. Front Med (Lausanne). 2022;9:970808.

Article  PubMed  Google Scholar 

Lang IM, Pesavento R, Bonderman D, Yuan JX. Risk factors and basic mechanisms of chronic thromboembolic pulmonary hypertension: a current understanding. Eur Respir J. 2013;41:462–8.

Article  PubMed  Google Scholar 

Dorfmuller P, Gunther S, Ghigna MR, Thomas de Montpreville V, Boulate D, Paul JF, et al. Microvascular disease in chronic thromboembolic pulmonary hypertension: a role for pulmonary veins and systemic vasculature. Eur Respir J. 2014;44:1275–88.

Article  PubMed  Google Scholar 

Lewczuk J, Piszko P, Jagas J, Porada A, Wojciak S, Sobkowicz B, et al. Prognostic factors in medically treated patients with chronic pulmonary embolism. Chest. 2001;119:818–23.

Article  CAS  PubMed  Google Scholar 

Ghofrani HA, Galiè N, Grimminger F, Grünig E, Humbert M, Jing ZC, et al. Riociguat for the treatment of pulmonary arterial hypertension. N Engl J Med. 2013;369:330–40.

Article  CAS  PubMed  Google Scholar 

Suh M. The COVID-19 era, is it OK to perform a perfusion-only SPECT/CT for the diagnosis of Pulmonary Embolism? Nucl Med Mol Imaging. 2022;56:67–70.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang L, Wang M, Yang T, Wu D, Xiong C, Fang W. A prospective, comparative study of Ventilation-Perfusion Planar Imaging and Ventilation-Perfusion SPECT for Chronic Thromboembolic Pulmonary Hypertension. J Nucl Med. 2020;61:1832–8.

Article  CAS  PubMed  Google Scholar