We thank the authors for commenting on our recent study.1

First, the authors point out and nicely describe a major limitation of our study2, stating: “In this study, missing information includes aneurysm location, aneurysm size, why a treatment was chosen, whether a pathology was a comorbidity or a complication, if there was an external ventricular drain, and all the details regarding the aneurysmal disease process. In short, we do not know if these cohorts are comparable.”

We fully agree with this major limitation of our study. When conducting the study we were aware of this limitation and included two paragraphs describing details of it in the Limitations section at the end of the discussion. Furthermore, we decided against sophisticated matching or weighting methods but showed unadjusted ORs as well as ORs that were adjusted for age, sex, the Charlson index and year of treatment only. Throughout the article we described both …