1   Department of Gastroenterology, Hospital da Senhora da Oliveira, Guimarães, Portugal (Ringgold ID: RIN70893)

2   Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal

3   ICVS/3B’s, PT Government Associate Laboratory, Braga, Portugal

,

Tiago Cúrdia Gonçalves

1   Department of Gastroenterology, Hospital da Senhora da Oliveira, Guimarães, Portugal (Ringgold ID: RIN70893)

2   Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal

3   ICVS/3B’s, PT Government Associate Laboratory, Braga, Portugal

,

Maria J. Moreira

1   Department of Gastroenterology, Hospital da Senhora da Oliveira, Guimarães, Portugal (Ringgold ID: RIN70893)

2   Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal

3   ICVS/3B’s, PT Government Associate Laboratory, Braga, Portugal

,

Francisca Dias de Castro

1   Department of Gastroenterology, Hospital da Senhora da Oliveira, Guimarães, Portugal (Ringgold ID: RIN70893)

2   Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal

3   ICVS/3B’s, PT Government Associate Laboratory, Braga, Portugal

,

Bernardo Sousa-Pinto

4   MEDCIDS, Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

5   CINTESIS, Center for Health Technology and Services Research, University of Porto, Porto, Portugal

,

Mário Dinis-Ribeiro

4   MEDCIDS, Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

6   RISE@CI-IPO (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto) / Porto Comprehensive Cancer Center (Porto.CCC), Porto, Portugal

,

José Cotter

1   Department of Gastroenterology, Hospital da Senhora da Oliveira, Guimarães, Portugal (Ringgold ID: RIN70893)

2   Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal

3   ICVS/3B’s, PT Government Associate Laboratory, Braga, Portugal

Registration number (trial ID): NCT04782986, Trial registry: ClinicalTrials.gov (http://www.clinicaltrials.gov/), Type of Study: Prospective, single-centre, single-blinded cohort study