Schulman H, Greengard P. Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable protein. Nature. 1978;271:478–9. https://doi.org/10.1038/271478a0.

Article  CAS  PubMed  Google Scholar 

Schulman H, Greengard P. Ca2+-dependent protein phosphorylation system in membranes from various tissues, and its activation by “calcium-dependent regulator.” Proc Natl Acad Sci USA. 1978;75:5432–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Walsh D, Perkins JP, Krebs EG. An adenosine 3’,5’-monophosphate-dependant protein kinase from rabbit skeletal muscle. J Biol Chem. 1968;10:3763–5.

Article  Google Scholar 

Reimann E, Walsh DA, Krebs EG. Purification and properties of rabbit skeletal muscle adenosine 3’5’-monophosphate-dependent protein kinases. J Biol Chem. 1971;246:1986–95.

Article  CAS  PubMed  Google Scholar 

Kennedy MB, McGuinness T, Greengard P. A calcium/calmodulin-dependent protein kinase from mammalian brain that phosphorylates Synapsin I: partial purification and characterization. J Neurosci. 1983;3:818–31. https://doi.org/10.1523/JNEUROSCI.03-04-00818.1983.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Walter U, Lohmann SM, Sieghart W, Greengard P. Identification of the cyclic AMP-dependent protein kinase responsible for endogenous phosphorylation of substrate proteins in synaptic membrane fraction from rat brain. J Biol Chem. 1979;254:12235–9.

Article  CAS  PubMed  Google Scholar 

Hell JW. How Ca2+-permeable AMPA receptors, the kinase PKA, and the phosphatase PP2B are intertwined in synaptic LTP and LTD. Sci Signal. 2016;9:e2. https://doi.org/10.1126/scisignal.aaf7067.

Article  CAS  PubMed  Google Scholar 

Sanderson JL, Dell’Acqua ML. AKAP signaling complexes in regulation of excitatory synaptic plasticity. Neuroscientist. 2011;17:321–36. https://doi.org/10.1177/1073858410384740.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang H, Peng RY. Basic roles of key molecules connected with NMDAR signaling pathway on regulating learning and memory and synaptic plasticity. Mil Med Res. 2016;3:26. https://doi.org/10.1186/s40779-016-0095-0.

Article  PubMed  PubMed Central  Google Scholar 

Abel T, Nguyen PV. Regulation of hippocampus-dependent memory by cyclic AMP-dependent protein kinase. Prog Brain Res. 2008;169:97–115. https://doi.org/10.1016/S0079-6123(07)00006-4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Christensen KR, Nairn AC. cAMP-regulated phosphoproteins DARPP-32, ARPP16/19, and RCS modulate striatal signal transduction through protein kinases and phosphatases. Adv Pharmacol. 2021;90:39–65. https://doi.org/10.1016/bs.apha.2020.09.005.

Article  CAS  PubMed  Google Scholar 

Uhler MD, Chrivia JC, McKnight GS. Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase”. J Biol Chem. 1986;261:15360–3.

Article  CAS  PubMed  Google Scholar 

Uhler MD, McKnight GS. Expression of cDNAs for two isoforms of the catalytic subunit of cAMP-dependent protein kinase. J Biol Chem. 1987;262:15202–7.

Article  CAS  PubMed  Google Scholar 

Jahnsen T, Hedin L, Kidd VJ, Schulz T, Richards JS. Molecular cloning of cDNA for a hormone-regulated isoform of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovaries. Methods Enzymol. 1988;159:318–24. https://doi.org/10.1016/0076-6879(88)59032-8.

Article  CAS  PubMed  Google Scholar 

Uhler MD, et al. Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1986;83:1300–4. https://doi.org/10.1073/pnas.83.5.1300.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zimmermann B, Chiorini JA, Ma Y, Kotin RM, Herberg FW. PrKX is a novel catalytic subunit of the cAMP-dependent protein kinase regulated by the regulatory subunit type I. J Biol Chem. 1999;274:5370–8. https://doi.org/10.1074/jbc.274.9.5370.

Article  CAS  PubMed  Google Scholar 

Beebe, S. J. S., P.; Jahnsen, T.; Li, Y. The C gamma subunit is a unique isozyme of the cAMP-dependent protein kinase. J Biol Chem 1992;267:25505–25512.

Schiebel K, et al. Abnormal XY interchange between a novel isolated protein kinase gene, PRKY, and its homologue, PRKX, accounts for one third of all (Y+)XX males and (Y-)XY females. Hum Mol Genet. 1997;6:1985–9. https://doi.org/10.1093/hmg/6.11.1985.

Article  CAS  PubMed  Google Scholar 

Taskén K, et al. The gene encoding the catalytic subunit C alpha of cAMP-dependent protein kinase (locus PRKACA) localizes to human chromosome region 19p13.1. Genomics. 1996;36:535–8. https://doi.org/10.1006/geno.1996.0501.

Article  PubMed  Google Scholar 

San Agustin JT, Witman GB. Differential expression of the C(s) and Calpha1 isoforms of the catalytic subunit of cyclic 3’,5’-adenosine monophosphate-dependent protein kinase testicular cells. Biol Reprod. 2001;65:151–64. https://doi.org/10.1095/biolreprod65.1.151.

Article  CAS  PubMed  Google Scholar 

Showers MO, Maurer RA. Cloning of cDNA for the catalytic subunit of cAMP-dependent protein kinase. Methods Enzymol. 1988;159:311–8. https://doi.org/10.1016/0076-6879(88)59031-6.

Article  CAS  PubMed  Google Scholar 

Showers MO, Maurer RA. A cloned bovine cDNA encodes an alternate form of the catalytic subunit of cAMP-dependent protein kinase. J Biol Chem. 1986;261:16288–91.

Article  CAS  PubMed  Google Scholar 

Guthrie CR, Skålhegg BS, McKnight GS. Two novel brain-specific splice variants of the murine Cbeta gene of cAMP-dependent protein kinase. J Biol Chem. 1997;272:29560–5. https://doi.org/10.1074/jbc.272.47.29560.

Article  CAS  PubMed  Google Scholar 

Wiemann, S. K., V.; Pyerin, W. Isoform C beta 2, an unusual form of the bovine catalytic subunit of cAMP-dependent protein kinase. J Biol Chem. 1991;266:5140–5146.

Ørstavik S, et al. Identification of novel splice variants of the human catalytic subunit Cbeta of cAMP-dependent protein kinase. Eur J Biochem. 2001;268:5066–73. https://doi.org/10.1046/j.0014-2956.2001.02429.x.

Article  PubMed  Google Scholar 

Kvissel AK, et al. Induction of Cbeta splice variants and formation of novel forms of protein kinase A type II holoenzymes during retinoic acid-induced differentiation of human NT2 cells. Cell Signal. 2004;16:577–87. https://doi.org/10.1016/j.cellsig.2003.08.014.

Article  CAS  PubMed  Google Scholar 

Soberg K, Moen LV, Skalhegg BS, Laerdahl JK. Evolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms. PLoS One. 2017;12:e0181091. https://doi.org/10.1371/journal.pone.0181091.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Funderud A, et al. Identification, cloning and characterization of a novel 47 kDa murine PKA C subunit homologous to human and bovine Cbeta2. BMC Biochem. 2006;7:20. https://doi.org/10.1186/1471-2091-7-20.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Beavo JA, Bechtel PJ, Krebs EG. Preparation of homogeneous cyclic AMP-dependent protein kinase(s) and its subunits from rabbit skeletal muscle. Methods Enzymol. 1974;38:299–308. https://doi.org/10.1016/0076-6879(74)38046-9.

Article  CAS  PubMed  Google Scholar 

Hofmann FB, Beavo JA, Bechtel PJ, Krebs EG. Comparison of adenosine 3’:5’-monophosphate-dependent protein kinases from rabbit skeletal and bovine heart muscle. J Biol Chem. 1975;250:7795–801.

Article  CAS  PubMed  Google Scholar 

Rosen OM, Rubin CS, Erlighman J. Properties of the cyclid AMP-dependent protein kinase from bovine and porcine heart. Adv Enzyme Regul. 1975;13:173–85. https://doi.org/10.1016/0065-2571(75)90014-x.

Article  CAS  PubMed  Google Scholar 

Taylor SS, Lee CY, Swain L, Stafford PH. Cyclic AMP-dependent protein kinase: purification of the holoenzyme by affinity chromatography. Anal Biochem. 1976;76:45–52. https://doi.org/10.1016/0003-2697(76)90262-1.

Article  CAS  PubMed  Google Scholar 

Scott JD, et al. The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain. Proc Natl Acad Sci U S A. 1987;84:5192–6. https://doi.org/10.1073/pnas.84.15.5192.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sandberg M, Tasken K, Oyen O, Hansson V, Jahnsen T. Molecular cloning, cDNA structure and deduced amino acid sequence for a type I regulatory subunit of cAMP-dependent protein kinase from human testis. Biochem Biophys Res Commun. 1987;149:939–45. https://doi.org/10.1016/0006-291x(87)90499-2.

Article  CAS  PubMed  Google Scholar 

Lee DC, Carmichael DF, Krebs EG, McKnight GS. Isolation of a cDNA clone for the type I regulatory subunit of bovine cAMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1983;80:3608–12.