aDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón

bMedicine Department, School of Medicine, Universidad Complutense de Madrid

cGregorio Marañón Health Research Institute, (IiSGM)

dDepartment of Dermatology, Hospital General Universitario Gregorio Marañón

eCIBER of Respiratory Diseases (CIBERES CB06/06/0058), Madrid, Spain

Correspondence to Emilio Bouza, MD, PhD, Clinical Microbiology and Infectious Diseases Department, Doctor Esquerdo 46, 28007 Madrid, Spain. Tel: +34 91 586 84 53; fax: +34 91 586 87 67; e-mail: [email protected]