Volume 209, February 2024, Pages 36-39Author links open overlay panel, , , , Abstract

A newborn male Holstein calf developed a nodular enlargement at the tip of the tongue. Histopathological examination of the mass revealed predominant proliferating small, round, spindloid or polygonal neoplastic cells with scattered myoblast- and myotube-like cells and multinuclear giant cells. Phosphotungstic acid haematoxylin staining revealed cytoplasmic cross-striations in a few neoplastic cells. Neoplastic cells were immunopositive for vimentin, desmin, myoD1, myogenin, myoglobin and α-smooth muscle actin. The mass was diagnosed as embryonal rhabdomyosarcoma. To the best of our knowledge, this is the first reported case of bovine congenital lingual rhabdomyosarcoma, which is rare in animals.

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This research did not receive any specific grant from funding agencies in the public, commercial or not-for-profit sectors.

Declaration of competing interests

The authors declared no conflicts of interest in relation to the research, authorship or publication of this article.

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