Breast conserving therapy is now considered the preferred option for early invasive and in situ ductal (DCIS) breast carcinoma. In an attempt to decrease positive margin and local recurrence, various methods for margin delineation have been described. Our team at AIIMS New Delhi have developed a new technique of injecting methylene blue at the sonographically determined margin of tumour to delineate the margin of excision for breast cancer. We perform this procedure after immobilization of tumour with a transparent Ioban/Opsite adhesive sheet applied over the breast. The injection of blue dye at sonographically determined margins facilitates the lumpectomy with free margins.