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Available online 23 January 2024
Author links open overlay panel, , , Highlights•Physical exercise can exert antitumorigenic effects; however, the molecular mechanisms are still poorly understood.
•Single-cell analysis may help to characterize the molecular mechanisms underlying the effects of exercise on anticancer immune function as well as on the complex tumor microenvironment.
•Recent research using single-cell analysis provides preliminary insights into the molecular mechanisms behind an improved antitumor immunity in response to exercise. Particularly, there is evidence for a “reprogramming” of several immune effectors towards a higher antitumoral toxicity.
© 2024 Published by Elsevier B.V. on behalf of Shanghai University of Sport.
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