Peripheral Glucocorticoid Metabolism Associated With Patient Severity in the PICU

1 Department of Pediatrics, Teine-Keijinkai Hospital, Sapporo, Japan.

2 Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan.

3 Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.

Drs. Sai and Wada conceptualized and designed the study and drafted the initial article. Drs. Ogiwara and Tamura carried out data collection and the initial analysis and revised the article. Dr. Chapman conceptualized the study and critically revised the article as submitted. All authors approved the final article as submitted and agree to be accountable for all aspects of the work.

The authors have disclosed that they do not have any potential conflicts of interest.

Drs. Sai and Wada contributed equally to this study.

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