Purpurolide C-based microneedle promotes macrophages-mediated diabetic wound healing via inhibiting TLR4-MD2 dimerization and MYD88 phosphorylation

Diabetes

Wound healing

Purpurolide C

Liposome and GelMA-based microneedle patches

Macrophage polarization

Inflammation

Drug delivery

Molecular mechanism

© 2023 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

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