Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris

Aboutalebi F, Lachinani L, Khazaei Y, Forouzanfar M, Nasr-Esfahani MH, Ghaedi K, Dormiani K (2018) An efficient method for bacterial production and activity assessment of recombinant human insulin like growth factor 1. Mol Biol Rep 45(6):1957–1966. https://doi.org/10.1007/s11033-018-4348-8

Article  CAS  PubMed  Google Scholar 

Araujo MS, Guastali MD, Paulini F, Silva AN, Tsunemi MH, Fontes PK, Castilho ACS, Landim-Alvarenga FC (2020) Molecular and cellular effects of insulin-like growth factor-1 and LongR3-IGF-1 on in vitro maturation of bovine oocytes: comparative study. Growth Horm IGF Res 55:101357. https://doi.org/10.1016/j.ghir.2020.101357

Article  CAS  PubMed  Google Scholar 

Bach LA (2004) The insulin-like growth factor system: towards clinical applications. Clin Biochem Rev 25(3):155–164

PubMed  PubMed Central  Google Scholar 

Baeshen MN, Bouback TA, Alzubaidi MA, Bora RS, Alotaibi MA, Alabbas OT, Alshahrani SM, Aljohani AA, Munshi RA, Al-Hejin A, Ahmed MM, Redwan EM, Ramadan HA, Saini KS, Baeshen NA (2016) Expression and purification of C-peptide containing insulin using Pichia pastoris expression system. Biomed Res Int 2016:3423685. https://doi.org/10.1155/2016/3423685

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barner C, Petersson M, Eden Engstrom B, Hoybye C (2012) Effects on insulin sensitivity and body composition of combination therapy with GH and IGF1 in GH deficient adults with type 2 diabetes. Eur J Endocrinol 167(5):697–703. https://doi.org/10.1530/EJE-12-0484

Article  CAS  PubMed  Google Scholar 

Bourbonnais Y, Bolin D, Shields D (1988) Secretion of somatostatin by Saccharomyces cerevisiae. Correct proteolytic processing of pro-alpha-factor-somatostatin hybrids requires the products of the KEX2 and STE13 genes. J Biol Chem 263(30):15342–15347

Article  CAS  PubMed  Google Scholar 

Brierley RA (1998) Secretion of recombinant human insulin-like growth factor I (IGF-I). Methods Mol Biol 103:149–177. https://doi.org/10.1385/0-89603-421-6:149

Article  CAS  PubMed  Google Scholar 

Chen X, Zaro JL, Shen WC (2013) Fusion protein linkers: property, design and functionality. Adv Drug Deliv Rev 65(10):1357–1369. https://doi.org/10.1016/j.addr.2012.09.039

Article  CAS  PubMed  Google Scholar 

Collins T, Gerday C, Feller G (2005) Xylanases, xylanase families and extremophilic xylanases. FEMS Microbiol Rev 29(1):3–23. https://doi.org/10.1016/j.femsre.2004.06.005

Article  CAS  PubMed  Google Scholar 

Cui L, Huang H, Zhang H, Wang X, Qin X, Tu T, Zhang J, Su X, Yu H, Bai Y, Luo H, Yao B, Wang Y (2022) Recombinant expression of hen egg white lysozyme with the assistance of xylanase fusion partner in Pichia pastoris. Bioengineered 13(5):13860–13871. https://doi.org/10.1080/21655979.2022.2084496

Article  CAS  PubMed  PubMed Central  Google Scholar 

Emamipour N, Vossoughi M, Mahboudi F, Golkar M, Fard-Esfahani P (2019) Soluble expression of IGF1 fused to DsbA in SHuffle T7 strain: optimization of expression and purification by Box-Behnken design. Appl Microbiol Biotechnol 103(8):3393–3406. https://doi.org/10.1007/s00253-019-09719-w

Article  CAS  PubMed  Google Scholar 

Fang W, Gao H, Cao Y, Shan A (2014) Cloning and expression of a xylanase xynB from Aspergillus niger IA-001 in Pichia pastoris. J Basic Microbiol 54(Suppl 1):S190–S199. https://doi.org/10.1002/jobm.201300078

Article  CAS  PubMed  Google Scholar 

Francis GL, Ross M, Ballard FJ, Milner SJ, Senn C, McNeil KA, Wallace JC, King R, Wells JR (1992) Novel recombinant fusion protein analogues of insulin-like growth factor (IGF)-I indicate the relative importance of IGF-binding protein and receptor binding for enhanced biological potency. J Mol Endocrinol 8(3):213–223. https://doi.org/10.1677/jme.0.0080213

Article  CAS  PubMed  Google Scholar 

Frysak Z, Schovanek J, Iacobone M, Karasek D (2015) Insulin-like growth factors in a clinical setting: review of IGF-I. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 159(3):347–351. https://doi.org/10.5507/bp.2015.041

Article  PubMed  Google Scholar 

Fuqua JS, Derr M, Rosenfeld RG, Hwa V (2012) Identification of a novel heterozygous IGF1 splicing mutation in a large kindred with familial short stature. Horm Res Paediatr 78(1):59–66. https://doi.org/10.1159/000337249

Article  CAS  PubMed  Google Scholar 

Goodrick JC, Xu M, Finnegan R, Schilling BM, Schiavi S, Hoppe H, Wan NC (2001) High-level expression and stabilization of recombinant human chitinase produced in a continuous constitutive Pichia pastoris expression system. Biotechnol Bioeng 74(6):492–497. https://doi.org/10.1002/bit.1140

Article  CAS  PubMed  Google Scholar 

Hakuno F, Takahashi SI (2018) IGF1 receptor signaling pathways. J Mol Endocrinol 61(1):T69–T86. https://doi.org/10.1530/JME-17-0311

Article  CAS  PubMed  Google Scholar 

Huang K, Chu Y, Qin X, Zhang J, Bai Y, Wang Y, Luo H, Huang H, Su X (2021) Recombinant production of two xylanase-somatostatin fusion proteins retaining somatostatin immunogenicity and xylanase activity in Pichia pastoris. Appl Microbiol Biotechnol 105(10):4167–4175. https://doi.org/10.1007/s00253-021-11298-8

Article  CAS  PubMed  Google Scholar 

Julius D, Blair L, Brake A, Sprague G, Thorner J (1983) Yeast alpha factor is processed from a larger precursor polypeptide: the essential role of a membrane-bound dipeptidyl aminopeptidase. Cell 32(3):839–852. https://doi.org/10.1016/0092-8674(83)90070-3

Article  CAS  PubMed  Google Scholar 

Karbalaei M, Rezaee SA, Farsiani H (2020) Pichia pastoris: a highly successful expression system for optimal synthesis of heterologous proteins. J Cell Physiol 235(9):5867–5881. https://doi.org/10.1002/jcp.29583

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khamsi F, Armstrong DT (1997) Interactions between follicle-stimulating hormone and growth factors in regulation of deoxyribonucleic acid synthesis in bovine granulosa cells. Biol Reprod 57(3):684–688. https://doi.org/10.1095/biolreprod57.3.684

Article  CAS  PubMed  Google Scholar 

Kim SO, Lee YI (1996) High-level expression and simple purification of recombinant human insulin-like growth factor I. J Biotechnol 48(1–2):97–105. https://doi.org/10.1016/0168-1656(96)01402-2

Article  CAS  PubMed  Google Scholar 

Miki H, Takagi M (2015) Design of serum-free medium for suspension culture of CHO cells on the basis of general commercial media. Cytotechnology 67(4):689–697. https://doi.org/10.1007/s10616-014-9778-0

Article  CAS  PubMed  Google Scholar 

Panahi M, Alli Z, Cheng X, Belbaraka L, Belgoudi J, Sardana R, Phipps J, Altosaar I (2004) Recombinant protein expression plasmids optimized for industrial E. coli fermentation and plant systems produce biologically active human insulin-like growth factor-1 in transgenic rice and tobacco plants. Transgenic Res 13(3):245–259. https://doi.org/10.1023/b:trag.0000034619.21613.d0

Article  CAS  PubMed  Google Scholar 

Puche JE, Castilla-Cortazar I (2012) Human conditions of insulin-like growth factor-I (IGF-I) deficiency. J Transl Med 10:224. https://doi.org/10.1186/1479-5876-10-224

Article  CAS  PubMed  PubMed Central  Google Scholar 

Romand S, Jostock T, Fornaro M, Schmidt J, Ritter A, Wilms B, Laux H (2016) Improving expression of recombinant human IGF-1 using IGF-1R knockout CHO cell lines. Biotechnol Bioeng 113(5):1094–1101. https://doi.org/10.1002/bit.25877

Article  CAS  PubMed  Google Scholar 

Rosenbloom AL (2009) Mecasermin (recombinant human insulin-like growth factor I). Adv Ther 26(1):40–54. https://doi.org/10.1007/s12325-008-0136-5

Article  CAS  PubMed  Google Scholar 

TurkanogluOzcelik A, Yilmaz S, Inan M (2019) Pichia pastoris promoters. Methods Mol Biol 1923:1997–2112. https://doi.org/10.1007/978-1-4939-9024-5_3

Article  CAS  Google Scholar 

Vai M, Brambilla L, Orlandi I, Rota N, Ranzi BM, Alberghina L, Porro D (2000) Improved secretion of native human insulin-like growth factor 1 from gas1 mutant Saccharomyces cerevisiae cells. Appl Environ Microbiol 66(12):5477–5479. https://doi.org/10.1128/AEM.66.12.5477-5479.2000

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wan A, Xu D, Liu K, Peng L, Cai Y, Chen Y, He Y, Yang J, Jin J, Li H (2017) Efficient expression of stable recombinant human insulin-like growth factor-1 fusion with human serum albumin in Chinese hamster ovary cells. Prep Biochem Biotechnol 47(7):678–686. https://doi.org/10.1080/10826068.2017.1303612

Article  CAS  PubMed  Google Scholar 

留言 (0)

沒有登入
gif