Screening of key functional components of Taohong Siwu Decoction on ischemic stroke treatment based on multiobjective optimization approach and experimental validation

Collaborators GBDS. Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the global burden of Disease Study 2016. Lancet Neurol. 2019;18(5):439–58.

Article  Google Scholar 

Mendelson SJ, Prabhakaran S. Diagnosis and management of transient ischemic attack and Acute ischemic stroke: a review. JAMA. 2021;325(11):1088–98.

Article  CAS  PubMed  Google Scholar 

Pierot L, Jarayaman M, Szikora I, Hirsch J, Baxter B, Miyachi S, Mahadevan J, Chong W, Mitchell PJ, Coulthard A, et al. Standards of Practice in Acute ischemic stroke intervention International Recommendations. Can J Neurol Sci. 2019;46(3):269–74.

Article  PubMed  Google Scholar 

Leigh R, Knutsson L, Zhou J, van Zijl PC. Imaging the physiological evolution of the ischemic penumbra in acute ischemic stroke. J Cereb Blood Flow Metab. 2018;38(9):1500–16.

Article  PubMed  Google Scholar 

Xu ZM, Liang X, Dai LL, Wang YF, Liu SJ, Wang LD, Qiu WR, Guo CY, Hu RX, Zhang YL, et al. [Evidence of clinical randomized controlled trial study in treatment of acute cerebral infarction with traditional chinese medicine in recent five years]. Zhongguo Zhong Yao Za Zhi. 2021;46(12):2942–8.

PubMed  Google Scholar 

Li J, Zhao X, Zhang Y, Wan H, He Y, Li X, Yu L, Jin W. Comparison of traditional chinese medicine in the long-term secondary Prevention for patients with ischemic stroke: a systematical analysis. Front Pharmacol. 2021;12:722975.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhu T, Wang L, Feng Y, Sun G, Sun X. Classical active ingredients and extracts of chinese Herbal Medicines: Pharmacokinetics, Pharmacodynamics, and Molecular Mechanisms for ischemic stroke. Oxid Med Cell Longev. 2021;2021:8868941.

Article  PubMed  PubMed Central  Google Scholar 

Huang C, Zheng C, Li Y, Wang Y, Lu A, Yang L. Systems pharmacology in drug discovery and therapeutic insight for herbal medicines. Brief Bioinform. 2014;15(5):710–33.

Article  PubMed  Google Scholar 

Yang HY, Liu ML, Luo P, Yao XS, Zhou H. Network pharmacology provides a systematic approach to understanding the treatment of ischemic heart diseases with traditional chinese medicine. Phytomedicine. 2022;104:154268.

Article  CAS  PubMed  Google Scholar 

Cheng C, Zhu R, Liu M, Yang H, Guo F, Du Q, Wang X, Li M, Song G, Qin R, et al. Kunxian capsule alleviates renal damage by inhibiting the JAK1/STAT1 pathway in lupus nephritis. J Ethnopharmacol. 2023;310:116349.

Article  CAS  PubMed  Google Scholar 

Guo J, Zhao Y, Wu X, Li G, Zhang Y, Song Y, Du Q. Mechanism exploration and prognosis study of Astragali Radix-Spreading hedyotis herb for the treatment of lung adenocarcinoma based on bioinformatics approaches and molecular dynamics simulation. Front Chem. 2023;11:1128671.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang K, Li K, Chen Y, Wei G, Yu H, Li Y, Meng W, Wang H, Gao L, Lu A, et al. Computational network pharmacology-based strategy to capture Key Functional Components and decode the mechanism of Chai-Hu-Shu-Gan-San in Treating Depression. Front Pharmacol. 2021;12:782060.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu Q, Yin CH, Li Y, Cai JQ, Yang HY, Huang YY, Zheng YX, Xiong K, Yu HL, Lu AP, et al. Detecting critical functional ingredients group and mechanism of Xuebijing Injection in Treating Sepsis. Front Pharmacol. 2021;12:769190.

Article  PubMed  PubMed Central  Google Scholar 

Kibble M, Saarinen N, Tang J, Wennerberg K, Makela S, Aittokallio T. Network pharmacology applications to map the unexplored target space and therapeutic potential of natural products. Nat Prod Rep. 2015;32(8):1249–66.

Article  CAS  PubMed  Google Scholar 

Gong X, Sucher NJ. Stroke therapy in traditional chinese medicine (TCM): prospects for drug discovery and development. Phytomedicine. 2002;9(5):478–84.

Article  CAS  PubMed  Google Scholar 

Pan L, Peng C, Wang L, Li L, Huang S, Fei C, Wang N, Chu F, Peng D, Duan X. Network pharmacology and experimental validation-based approach to understand the effect and mechanism of Taohong Siwu decoction against ischemic stroke. J Ethnopharmacol. 2022;294:115339.

Article  CAS  PubMed  Google Scholar 

Yang YL, Liu CF, Huang JY, Yang HJ, Zhong WL, Li HH, Du SY, Bai J. [Analysis on quality value transfer of substance benchmarks of Taohong Siwu Decoction]. Zhongguo Zhong Yao Za Zhi. 2021;46(4):801–9.

PubMed  Google Scholar 

Shi Y, Liu Q, Chen W, Wang R, Wang L, Liu ZQ, Duan XC, Zhang Y, Shen A, Peng D, et al. Protection of Taohong Siwu Decoction on PC12 cells injured by oxygen glucose deprivation/reperfusion via mitophagy-NLRP3 inflammasome pathway in vitro. J Ethnopharmacol. 2023;301:115784.

Article  CAS  PubMed  Google Scholar 

Wang N, Fei C, Chu F, Huang S, Pan L, Peng D, Duan X. Taohong Siwu Decoction regulates cell necrosis and neuroinflammation in the Rat Middle cerebral artery occlusion model. Front Pharmacol. 2021;12:732358.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang M, Liu Z, Hu S, Duan X, Zhang Y, Peng C, Peng D, Han L. Taohong Siwu Decoction ameliorates ischemic stroke Injury Via suppressing pyroptosis. Front Pharmacol. 2020;11:590453.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mao Z, Tian L, Liu J, Wu Q, Wang N, Wang G, Wang Y, Seto S. Ligustilide ameliorates hippocampal neuronal injury after cerebral ischemia reperfusion through activating PINK1/Parkin-dependent mitophagy. Phytomedicine. 2022;101:154111.

Article  CAS  PubMed  Google Scholar 

Wu Q, Mao Z, Liu J, Huang J, Wang N. Ligustilide attenuates Ischemia Reperfusion-Induced hippocampal neuronal apoptosis via activating the PI3K/Akt pathway. Front Pharmacol. 2020;11:979.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cheng CY, Huang HC, Kao ST, Lee YC. Angelica sinensis extract promotes neuronal survival by enhancing p38 MAPK-mediated hippocampal neurogenesis and dendritic growth in the chronic phase of transient global cerebral ischemia in rats. J Ethnopharmacol. 2021;278:114301.

Article  CAS  PubMed  Google Scholar 

Zhang Y, Liu Y, Cui Q, Fu Z, Yu H, Liu A, Liu J, Qin X, Ge S, Zhang G. Hydroxysafflor Yellow A alleviates ischemic stroke in rats via HIF-1[Formula: see text], BNIP3, and Notch1-Mediated inhibition of Autophagy. Am J Chin Med. 2022;50(3):799–815.

Article  CAS  PubMed  Google Scholar 

Li Y, Liu XT, Zhang PL, Li YC, Sun MR, Wang YT, Wang SP, Yang H, Liu BL, Wang M et al. Hydroxysafflor Yellow A Blocks HIF-1alpha Induction of NOX2 and Protects ZO-1 Protein in Cerebral Microvascular Endothelium. Antioxid (Basel) 2022, 11(4).

Ru J, Li P, Wang J, Zhou W, Li B, Huang C, Li P, Guo Z, Tao W, Yang Y, et al. TCMSP: a database of systems pharmacology for drug discovery from herbal medicines. J Cheminform. 2014;6:13.

Article  PubMed  PubMed Central  Google Scholar 

Chen X, Zhou H, Liu YB, Wang JF, Li H, Ung CY, Han LY, Cao ZW, Chen YZ. Database of traditional chinese medicine and its application to studies of mechanism and to prescription validation. Br J Pharmacol. 2006;149(8):1092–103.

Article  CAS  PubMed  PubMed Central  Google Scholar 

O’Boyle NM, Morley C, Hutchison GR. Pybel: a Python wrapper for the OpenBabel cheminformatics toolkit. Chem Cent J. 2008;2:5.

Article  PubMed  PubMed Central  Google Scholar 

Xiong G, Wu Z, Yi J, Fu L, Yang Z, Hsieh C, Yin M, Zeng X, Wu C, Lu A, et al. ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties. Nucleic Acids Res. 2021;49(W1):W5–W14.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Keiser MJ, Roth BL, Armbruster BN, Ernsberger P, Irwin JJ, Shoichet BK. Relating protein pharmacology by ligand chemistry. Nat Biotechnol. 2007;25(2):197–206.

Article  CAS  PubMed  Google Scholar 

Hamad S, Adornetto G, Naveja JJ, Chavan Ravindranath A, Raffler J, Campillos M. HitPickV2: a web server to predict targets of chemical compounds. Bioinformatics. 2019;35(7):1239–40.

Article  CAS  PubMed  Google Scholar 

Daina A, Michielin O, Zoete V. SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules. Nucleic Acids Res. 2019;47(W1):W357–64.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pinero J, Ramirez-Anguita JM, Sauch-Pitarch J, Ronzano F, Centeno E, Sanz F, Furlong LI. The DisGeNET knowledge platform for disease genomics: 2019 update. Nucleic Acids Res. 2020;48(D1):D845–55.

CAS  PubMed  Google Scholar 

Oughtred R, Stark C, Breitkreutz BJ, Rust J, Boucher L, Chang C, Kolas N, O’Donnell L, Leung G, McAdam R, et al. The BioGRID interaction database: 2019 update. Nucleic Acids Res. 2019;47(D1):D529–41.

Article  CAS  PubMed  Google Scholar 

Pertea M, Kim D, Pertea GM, Leek JT, Salzberg SL. Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown. Nat Protoc. 2016;11(9):1650–67.

Article  CAS  PubMed  PubMed Central 

留言 (0)

沒有登入
gif