Collaborators GBDS. Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the global burden of Disease Study 2016. Lancet Neurol. 2019;18(5):439–58.
Mendelson SJ, Prabhakaran S. Diagnosis and management of transient ischemic attack and Acute ischemic stroke: a review. JAMA. 2021;325(11):1088–98.
Article CAS PubMed Google Scholar
Pierot L, Jarayaman M, Szikora I, Hirsch J, Baxter B, Miyachi S, Mahadevan J, Chong W, Mitchell PJ, Coulthard A, et al. Standards of Practice in Acute ischemic stroke intervention International Recommendations. Can J Neurol Sci. 2019;46(3):269–74.
Leigh R, Knutsson L, Zhou J, van Zijl PC. Imaging the physiological evolution of the ischemic penumbra in acute ischemic stroke. J Cereb Blood Flow Metab. 2018;38(9):1500–16.
Xu ZM, Liang X, Dai LL, Wang YF, Liu SJ, Wang LD, Qiu WR, Guo CY, Hu RX, Zhang YL, et al. [Evidence of clinical randomized controlled trial study in treatment of acute cerebral infarction with traditional chinese medicine in recent five years]. Zhongguo Zhong Yao Za Zhi. 2021;46(12):2942–8.
Li J, Zhao X, Zhang Y, Wan H, He Y, Li X, Yu L, Jin W. Comparison of traditional chinese medicine in the long-term secondary Prevention for patients with ischemic stroke: a systematical analysis. Front Pharmacol. 2021;12:722975.
Article CAS PubMed PubMed Central Google Scholar
Zhu T, Wang L, Feng Y, Sun G, Sun X. Classical active ingredients and extracts of chinese Herbal Medicines: Pharmacokinetics, Pharmacodynamics, and Molecular Mechanisms for ischemic stroke. Oxid Med Cell Longev. 2021;2021:8868941.
Article PubMed PubMed Central Google Scholar
Huang C, Zheng C, Li Y, Wang Y, Lu A, Yang L. Systems pharmacology in drug discovery and therapeutic insight for herbal medicines. Brief Bioinform. 2014;15(5):710–33.
Yang HY, Liu ML, Luo P, Yao XS, Zhou H. Network pharmacology provides a systematic approach to understanding the treatment of ischemic heart diseases with traditional chinese medicine. Phytomedicine. 2022;104:154268.
Article CAS PubMed Google Scholar
Cheng C, Zhu R, Liu M, Yang H, Guo F, Du Q, Wang X, Li M, Song G, Qin R, et al. Kunxian capsule alleviates renal damage by inhibiting the JAK1/STAT1 pathway in lupus nephritis. J Ethnopharmacol. 2023;310:116349.
Article CAS PubMed Google Scholar
Guo J, Zhao Y, Wu X, Li G, Zhang Y, Song Y, Du Q. Mechanism exploration and prognosis study of Astragali Radix-Spreading hedyotis herb for the treatment of lung adenocarcinoma based on bioinformatics approaches and molecular dynamics simulation. Front Chem. 2023;11:1128671.
Article CAS PubMed PubMed Central Google Scholar
Wang K, Li K, Chen Y, Wei G, Yu H, Li Y, Meng W, Wang H, Gao L, Lu A, et al. Computational network pharmacology-based strategy to capture Key Functional Components and decode the mechanism of Chai-Hu-Shu-Gan-San in Treating Depression. Front Pharmacol. 2021;12:782060.
Article CAS PubMed PubMed Central Google Scholar
Wu Q, Yin CH, Li Y, Cai JQ, Yang HY, Huang YY, Zheng YX, Xiong K, Yu HL, Lu AP, et al. Detecting critical functional ingredients group and mechanism of Xuebijing Injection in Treating Sepsis. Front Pharmacol. 2021;12:769190.
Article PubMed PubMed Central Google Scholar
Kibble M, Saarinen N, Tang J, Wennerberg K, Makela S, Aittokallio T. Network pharmacology applications to map the unexplored target space and therapeutic potential of natural products. Nat Prod Rep. 2015;32(8):1249–66.
Article CAS PubMed Google Scholar
Gong X, Sucher NJ. Stroke therapy in traditional chinese medicine (TCM): prospects for drug discovery and development. Phytomedicine. 2002;9(5):478–84.
Article CAS PubMed Google Scholar
Pan L, Peng C, Wang L, Li L, Huang S, Fei C, Wang N, Chu F, Peng D, Duan X. Network pharmacology and experimental validation-based approach to understand the effect and mechanism of Taohong Siwu decoction against ischemic stroke. J Ethnopharmacol. 2022;294:115339.
Article CAS PubMed Google Scholar
Yang YL, Liu CF, Huang JY, Yang HJ, Zhong WL, Li HH, Du SY, Bai J. [Analysis on quality value transfer of substance benchmarks of Taohong Siwu Decoction]. Zhongguo Zhong Yao Za Zhi. 2021;46(4):801–9.
Shi Y, Liu Q, Chen W, Wang R, Wang L, Liu ZQ, Duan XC, Zhang Y, Shen A, Peng D, et al. Protection of Taohong Siwu Decoction on PC12 cells injured by oxygen glucose deprivation/reperfusion via mitophagy-NLRP3 inflammasome pathway in vitro. J Ethnopharmacol. 2023;301:115784.
Article CAS PubMed Google Scholar
Wang N, Fei C, Chu F, Huang S, Pan L, Peng D, Duan X. Taohong Siwu Decoction regulates cell necrosis and neuroinflammation in the Rat Middle cerebral artery occlusion model. Front Pharmacol. 2021;12:732358.
Article CAS PubMed PubMed Central Google Scholar
Wang M, Liu Z, Hu S, Duan X, Zhang Y, Peng C, Peng D, Han L. Taohong Siwu Decoction ameliorates ischemic stroke Injury Via suppressing pyroptosis. Front Pharmacol. 2020;11:590453.
Article CAS PubMed PubMed Central Google Scholar
Mao Z, Tian L, Liu J, Wu Q, Wang N, Wang G, Wang Y, Seto S. Ligustilide ameliorates hippocampal neuronal injury after cerebral ischemia reperfusion through activating PINK1/Parkin-dependent mitophagy. Phytomedicine. 2022;101:154111.
Article CAS PubMed Google Scholar
Wu Q, Mao Z, Liu J, Huang J, Wang N. Ligustilide attenuates Ischemia Reperfusion-Induced hippocampal neuronal apoptosis via activating the PI3K/Akt pathway. Front Pharmacol. 2020;11:979.
Article CAS PubMed PubMed Central Google Scholar
Cheng CY, Huang HC, Kao ST, Lee YC. Angelica sinensis extract promotes neuronal survival by enhancing p38 MAPK-mediated hippocampal neurogenesis and dendritic growth in the chronic phase of transient global cerebral ischemia in rats. J Ethnopharmacol. 2021;278:114301.
Article CAS PubMed Google Scholar
Zhang Y, Liu Y, Cui Q, Fu Z, Yu H, Liu A, Liu J, Qin X, Ge S, Zhang G. Hydroxysafflor Yellow A alleviates ischemic stroke in rats via HIF-1[Formula: see text], BNIP3, and Notch1-Mediated inhibition of Autophagy. Am J Chin Med. 2022;50(3):799–815.
Article CAS PubMed Google Scholar
Li Y, Liu XT, Zhang PL, Li YC, Sun MR, Wang YT, Wang SP, Yang H, Liu BL, Wang M et al. Hydroxysafflor Yellow A Blocks HIF-1alpha Induction of NOX2 and Protects ZO-1 Protein in Cerebral Microvascular Endothelium. Antioxid (Basel) 2022, 11(4).
Ru J, Li P, Wang J, Zhou W, Li B, Huang C, Li P, Guo Z, Tao W, Yang Y, et al. TCMSP: a database of systems pharmacology for drug discovery from herbal medicines. J Cheminform. 2014;6:13.
Article PubMed PubMed Central Google Scholar
Chen X, Zhou H, Liu YB, Wang JF, Li H, Ung CY, Han LY, Cao ZW, Chen YZ. Database of traditional chinese medicine and its application to studies of mechanism and to prescription validation. Br J Pharmacol. 2006;149(8):1092–103.
Article CAS PubMed PubMed Central Google Scholar
O’Boyle NM, Morley C, Hutchison GR. Pybel: a Python wrapper for the OpenBabel cheminformatics toolkit. Chem Cent J. 2008;2:5.
Article PubMed PubMed Central Google Scholar
Xiong G, Wu Z, Yi J, Fu L, Yang Z, Hsieh C, Yin M, Zeng X, Wu C, Lu A, et al. ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties. Nucleic Acids Res. 2021;49(W1):W5–W14.
Article CAS PubMed PubMed Central Google Scholar
Keiser MJ, Roth BL, Armbruster BN, Ernsberger P, Irwin JJ, Shoichet BK. Relating protein pharmacology by ligand chemistry. Nat Biotechnol. 2007;25(2):197–206.
Article CAS PubMed Google Scholar
Hamad S, Adornetto G, Naveja JJ, Chavan Ravindranath A, Raffler J, Campillos M. HitPickV2: a web server to predict targets of chemical compounds. Bioinformatics. 2019;35(7):1239–40.
Article CAS PubMed Google Scholar
Daina A, Michielin O, Zoete V. SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules. Nucleic Acids Res. 2019;47(W1):W357–64.
Article CAS PubMed PubMed Central Google Scholar
Pinero J, Ramirez-Anguita JM, Sauch-Pitarch J, Ronzano F, Centeno E, Sanz F, Furlong LI. The DisGeNET knowledge platform for disease genomics: 2019 update. Nucleic Acids Res. 2020;48(D1):D845–55.
Oughtred R, Stark C, Breitkreutz BJ, Rust J, Boucher L, Chang C, Kolas N, O’Donnell L, Leung G, McAdam R, et al. The BioGRID interaction database: 2019 update. Nucleic Acids Res. 2019;47(D1):D529–41.
Article CAS PubMed Google Scholar
Pertea M, Kim D, Pertea GM, Leek JT, Salzberg SL. Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown. Nat Protoc. 2016;11(9):1650–67.
留言 (0)