Side population cells derived from hUCMSCs and hPMSCs could inhibit the malignant behaviors of Tn+ colorectal cancer cells from modifying their O-glycosylation status

You W, Di A, Zhang L, Zhao G. Effects of wogonin on the growth and metastasis of colon cancer through the Hippo signaling pathway. Bioengineered. 2022;13(2):2586–97.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pan X, Li B, Zhang G, Gong Y, Liu R, Chen B, et al. Identification of RORgamma as a favorable biomarker for colon cancer. J Int Med Res. 2021;49(5):3000605211008338.

Article  CAS  PubMed  Google Scholar 

Meng F, Cao Y, Su H, Liu T, Tian L, Zhang Y, et al. Newcastle disease virus expressing an angiogenic inhibitor exerts an enhanced therapeutic efficacy in colon cancer model. PLoS ONE. 2022;17(4): e0264896.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Moghadamyeghaneh Z, Hanna MH, Hwang G, Mills S, Pigazzi A, Stamos MJ, et al. Outcomes of colon resection in patients with metastatic colon cancer. Am J Surg. 2016;212(2):264–71.

Article  PubMed  Google Scholar 

Klaver CEL, Kappen TM, Borstlap WAA, Bemelman WA, Tanis PJ. Laparoscopic surgery for T4 colon cancer: a systematic review and meta-analysis. Surg Endosc. 2017;31(12):4902–12.

Article  PubMed  PubMed Central  Google Scholar 

O’Malley G, Heijltjes M, Houston AM, Rani S, Ritter T, Egan LJ, et al. Mesenchymal stromal cells (MSCs) and colorectal cancer: a troublesome twosome for the anti-tumour immune response? Oncotarget. 2016;7(37):60752–74.

Article  PubMed  PubMed Central  Google Scholar 

Wang S, Miao Z, Yang Q, Wang Y, Zhang J. The dynamic roles of mesenchymal stem cells in colon cancer. Can J Gastroenterol Hepatol. 2018;2018:7628763.

Article  PubMed  PubMed Central  Google Scholar 

El-Said MM, Emile SH. Cellular therapy: a promising tool in the future of colorectal surgery. World J Gastroenterol. 2019;25(13):1560–5.

Article  PubMed  PubMed Central  Google Scholar 

Yi X, Chen F, Liu F, Peng Q, Li Y, Li S, et al. Comparative separation methods and biological characteristics of human placental and umbilical cord mesenchymal stem cells in serum-free culture conditions. Stem Cell Res Ther. 2020;11(1):183.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nombela-Arrieta C, Ritz J, Silberstein LE. The elusive nature and function of mesenchymal stem cells. Nat Rev Mol Cell Biol. 2011;12(2):126–31.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999;284(5411):143–7.

Article  CAS  PubMed  Google Scholar 

Behbod F, Vivanco MD. Side population. Methods Mol Biol. 2015;1293:73–81.

Article  PubMed  Google Scholar 

Golebiewska A, Brons NH, Bjerkvig R, Niclou SP. Critical appraisal of the side population assay in stem cell and cancer stem cell research. Cell Stem Cell. 2011;8(2):136–47.

Article  CAS  PubMed  Google Scholar 

Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med. 1996;183(4):1797–806.

Article  CAS  PubMed  Google Scholar 

Goodell MA, Rosenzweig M, Kim H, Marks DF, DeMaria M, Paradis G, et al. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat Med. 1997;3(12):1337–45.

Article  CAS  PubMed  Google Scholar 

Kato K, Takao T, Kuboyama A, Tanaka Y, Ohgami T, Yamaguchi S, et al. Endometrial cancer side-population cells show prominent migration and have a potential to differentiate into the mesenchymal cell lineage. Am J Pathol. 2010;176(1):381–92.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gupta R, Leon F, Rauth S, Batra SK, Ponnusamy MP. A systematic review on the implications of O-linked glycan branching and truncating enzymes on cancer progression and metastasis. Cells. 2020;9(2):446.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dong X, Jiang Y, Liu J, Liu Z, Gao T, An G, et al. T-synthase deficiency enhances oncogenic features in human colorectal cancer cells via activation of epithelial-mesenchymal transition. Biomed Res Int. 2018;2018:9532389.

Article  PubMed  PubMed Central  Google Scholar 

Iwai T, Inaba N, Naundorf A, Zhang Y, Gotoh M, Iwasaki H, et al. Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans. J Biol Chem. 2002;277(15):12802–9.

Article  CAS  PubMed  Google Scholar 

Hofmann BT, Schluter L, Lange P, Mercanoglu B, Ewald F, Folster A, et al. COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer. Mol Cancer. 2015;14:109.

Article  PubMed  PubMed Central  Google Scholar 

Jiang Y, Liu Z, Xu F, Dong X, Cheng Y, Hu Y, et al. Aberrant O-glycosylation contributes to tumorigenesis in human colorectal cancer. J Cell Mol Med. 2018;22(10):4875–85.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun X, Ju T, Cummings RD. Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers. BMC Cancer. 2018;18(1):827.

Article  PubMed  PubMed Central  Google Scholar 

Itzkowitz SH, Yuan M, Montgomery CK, Kjeldsen T, Takahashi HK, Bigbee WL, Kim YS. Expression of Tn, sialosyl-Tn, and T antigens in human colon cancer. Cancer Res. 1989;49(1):197–204.

CAS  PubMed  Google Scholar 

Fu C, Zhao H, Wang Y, Cai H, Xiao Y, Zeng Y, et al. Tumor-associated antigens: Tn antigen, sTn antigen, and T antigen. HLA. 2016;88(6):275–86.

Article  CAS  PubMed  Google Scholar 

Yu X, Du Z, Sun X, Shi C, Zhang H, Hu T. Aberrant Cosmc genes result in Tn antigen expression in human colorectal carcinoma cell line HT-29. Int J Clin Exp Pathol. 2015;8(3):2590–602.

PubMed  PubMed Central  Google Scholar 

Ju T, Lanneau GS, Gautam T, Wang Y, Xia B, Stowell SR, et al. Human tumor antigens Tn and sialyl Tn arise from mutations in Cosmc. Cancer Res. 2008;68(6):1636–46.

Article  CAS  PubMed  Google Scholar 

Zhang A, Zhang J, Li X, Zhang H, Xiong Y, Wang Z, et al. hPMSCs inhibit the expression of PD-1 in CD4(+)IL-10(+) T cells and mitigate liver damage in a GVHD mouse model by regulating the crosstalk between Nrf2 and NF-kappaB signaling pathway. Stem Cell Res Ther. 2021;12(1):368.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ding R, Hu X, Hu W, Du Z, Huang P, Wang M, et al. Cosmc transfection decreases malignant behavior of Tn(+) cells and enhances sensitivity to apoptosis when induced by Apo2L/TRAIL via alteration of O-glycan structure. Aging (Albany NY). 2021;13(19):23393–406.

Article  CAS  PubMed  Google Scholar 

Dowling CM, Herranz Ors C, Kiely PA. Using real-time impedance-based assays to monitor the effects of fibroblast-derived media on the adhesion, proliferation, migration and invasion of colon cancer cells. Biosci Rep. 2014;34:4.

Article  Google Scholar 

Ju T, Xia B, Aryal RP, Wang W, Wang Y, Ding X, et al. A novel fluorescent assay for T-synthase activity. Glycobiology. 2011;21(3):352–62.

Article  CAS  PubMed  Google Scholar 

Kudelka MR, Antonopoulos A, Wang Y, Duong DM, Song X, Seyfried NT, et al. Cellular O-glycome reporter/amplification to explore O-glycans of living cells. Nat Methods. 2016;13(1):81–6.

Article  CAS  PubMed  Google Scholar 

Francois S, Usunier B, Forgue-Lafitte ME, L’Homme B, Benderitter M, Douay L, et al. Mesenchymal stem cell administration attenuates colon cancer progression by modulating the immune component within the colorectal tumor microenvironment. Stem Cells Transl Med. 2019;8(3):285–300.

Article  CAS  PubMed  Google Scholar 

Wakao S, Akashi H, Kushida Y, Dezawa M. Muse cells, newly found non-tumorigenic pluripotent stem cells, reside in human mesenchymal tissues. Pathol Int. 2014;64(1):1–9.

Article  CAS  PubMed  Google Scholar 

Young W. Future of muse cells. Adv Exp Med Biol. 2018;1103:309–15.

Article  CAS  PubMed  Google Scholar 

Liu Z, Liu J, Dong X, Hu X, Jiang Y, Li L, et al. Tn antigen promotes human colorectal cancer metastasis via H-Ras mediated epithelial-mesenchymal transition activation. J Cell Mol Med. 2019;23(3):2083–92.

Article  CAS  PubMed  PubMed Central  Google Scholar 

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