Ko J. Neuroanatomical substrates of Rodent Social Behavior: the medial prefrontal cortex and its projection patterns. Front Neural Circuits. 2017;11:41.

Article  PubMed  PubMed Central  Google Scholar 

Robinson GE, Fernald RD, Clayton DF. Genes and social behavior. Sci (80-). 2008;322:896–900.

Article  CAS  Google Scholar 

Chen P, Hong W. Neural Circuit Mechanisms of Social Behavior Neuron. 2018;98:16–30.

CAS  PubMed  Google Scholar 

Rutter M, et al. Quasi-autistic patterns following severe early global privation. English and Romanian Adoptees (ERA) study team. J Child Psychol Psychiatry. 1999;40:537–49.

Article  CAS  PubMed  Google Scholar 

Volkmar FR, Pauls D, Autism. Lancet. 2003;362:1133–41.

Article  PubMed  Google Scholar 

Ozonoff S, Heung K, Byrd R, Hansen R. Hertz-Picciotto, I. The onset of Autism: patterns of Symptom Emergence in the First Years of Life. Autism Res. 2008;1:320–8.

Article  PubMed  PubMed Central  Google Scholar 

Garber K, Visootsak J, Warren J. Fragile X syndrome. Eur J Hum Genet. 2008;1:666–72.

Article  Google Scholar 

Penn DL, Corrigan PW, Bentall RP, Racenstein JM, Newman L. Social Cognition in Schizophrenia. Psychol Bull. 1997;121:114–32.

Article  CAS  PubMed  Google Scholar 

Levy SE, Mandell DS, Schultz RT, Autism. Lancet. 2009;374:1627–38.

Article  PubMed  PubMed Central  Google Scholar 

Lai M, Lombardo MV. Baron-cohen, S. Autism. Lancet. 2014;383:896–910.

Article  PubMed  Google Scholar 

Constantino JN, Charman T. Diagnosis of autism spectrum disorder: reconciling the syndrome, its diverse origins, and variation in expression. Lancet Neurol. 2016;15:279–91.

Article  PubMed  Google Scholar 

Courchesne E, et al. Mapping early Brain Development in Autism. Neuron. 2007;56:399–413.

Article  CAS  PubMed  Google Scholar 

Insel TR, Fernald RD. How the brain processes social information: searching for the Social Brain. Annu Rev Neurosci. 2004;27:697–722.

Article  CAS  PubMed  Google Scholar 

Beckstead RM. An Autoradiographic Examination of Corticocortical and Subcortical Projections of the Mediodorsal-Projection (Prefrontal) Cortex in the Rat. J Comp Neurol 43–62 (1979).

Oades RD, Halliday GM. Ventral tegmental (A10) system: neurobiology. 1. Anatomy and connectivity. Brain Res Rev. 1987;12:117–65.

Article  Google Scholar 

Dölen G, Darvishzadeh A, Huang KW, Malenka RC. Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin. Nature. 2013;501:179–84.

Article  PubMed  PubMed Central  Google Scholar 

Gunaydin LA, et al. Natural neural projection dynamics underlying social behavior. Cell. 2014;157:1535–51.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yizhar O, et al. Neocortical excitation / inhibition balance in information processing and social dysfunction. Nature. 2011;477:171–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bicks LK, Koike H, Akbarian S, Morishita H. Prefrontal Cortex and Social Cognition in Mouse and Man. Front Psychol. 2015;6:1–15.

Article  Google Scholar 

Rogers-Carter MM, Djerdjaj A, Gribbons KB, Varela JA, Christianson JP. Insular cortex projections to nucleus accumbens core mediate social approach to stressed juvenile rats. J Neurosci. 2019;39:8717–29.

Article  PubMed  PubMed Central  Google Scholar 

Williams AV, et al. Social approach and social vigilance are differentially regulated by oxytocin receptors in the nucleus accumbens. Neuropsychopharmacology. 2020;45:1423–30.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Okuyama T, Kitamura T, Roy D, Itohara S, Tonegawa S. Ventral CA1 neurons store social memory. Sci (80-). 2016;353:1536–41.

Article  CAS  Google Scholar 

Park G, et al. Social isolation impairs the prefrontal-nucleus accumbens circuit subserving social recognition in mice. Cell Rep. 2021;35:109104.

Article  CAS  PubMed  Google Scholar 

Xing B, et al. A subpopulation of prefrontal cortical neurons is required for Social Memory. Biol Psychiatry. 2021;89:521–31.

Article  CAS  PubMed  Google Scholar 

Murugan M et al. Combined Social and Spatial Coding in a Descending Projection from the Prefrontal Cortex Combined Social and Spatial Coding in a Descending Projection from the Prefrontal Cortex. Cell 1–15 (2017) doi:https://doi.org/10.1016/j.cell.2017.11.002.

Heshmati M, et al. Depression and social defeat stress are associated with inhibitory synaptic changes in the nucleus accumbens. J Neurosci. 2020;40:6228–33.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bagot RC, et al. Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression. Nat Commun. 2015;6:7062.

Article  CAS  PubMed  Google Scholar 

Nam H, et al. Reduced nucleus accumbens enkephalins underlie vulnerability to social defeat stress. Neuropsychopharmacology. 2019;44:1876–85.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chaudhury D, et al. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature. 2013;493:532–6.

Article  CAS  PubMed  Google Scholar 

Vialou V, et al. Prefrontal cortical circuit for Depression- and anxiety- related behaviors mediated by cholecystokinin: role of FosB. J Neurosci. 2014;34:3878–87.

Article  PubMed  PubMed Central  Google Scholar 

Dichter GS, et al. Reward circuitry function in autism spectrum disorders. SCAN. 2012;160–72. https://doi.org/10.1093/scan/nsq095.

Nehrkorn B, et al. Reward system dysfunction in autism spectrum disorders. SCAN. 2013;565–72. https://doi.org/10.1093/scan/nss033.

Zeeland AAS, Dapretto M, Ghahremani DG, Poldrack RA, Bookheimer SY. Reward Processing in Autism. Autism Res. 2010;3:53–67.

Google Scholar 

D’Cruz A-M, Mosconi MW, Ragozzino ME, Cook EH, Sweeney JA. Alterations in the functional neural circuitry supporting fl exible choice behavior in autism spectrum disorders. Transl Psychiatry 1–9 (2016) doi:https://doi.org/10.1038/tp.2016.161.

Langen M et al. Fronto-striatal circuitry and inhibitory control in autism: Findings from diffusion tensor imaging tractography. Cortex 48, (2012).

Martino A, Di, et al. Aberrant Striatal Functional Connectivity in Children with Autism. BPS. 2010;69:847–56.

Google Scholar 

Rothwell PE, et al. Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors. Cell. 2014;158:198–212.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Neuhofer D, et al. Functional and structural deficits at accumbens synapses in a mouse model of Fragile X. Front Cell Neurosci. 2015;9:1–15.

Article  Google Scholar 

Platt RJ, et al. Chd8 mutation leads to autistic-like behaviors and impaired Striatal circuits. Cell Rep. 2017;19:335–50.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bukatova S, et al. Shank3 Deficiency is Associated with altered Profile of neurotransmission markers in pups and adult mice. Neurochem Res. 2021;46:3342–55.

Article  CAS  PubMed  Google Scholar 

Tzanoulinou S, et al. Inhibition of Trpv4 rescues circuit and social deficits unmasked by acute inflammatory response in a Shank3 mouse model of Autism. Mol Psychiatry. 2022. https://doi.org/10.1038/s41380-021-01427-0.

Article  PubMed  PubMed Central  Google Scholar 

Walsh JJ, et al. 5-HT release in nucleus accumbens rescues social deficits in mouse autism model. Nature. 2018;560:589–94.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Folkes OM, et al. An endocannabinoid-regulated basolateral amygdala-nucleus accumbens circuit modulates sociability. J Clin Invest. 2020;130:1728–42.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Choe KY, et al. Oxytocin normalizes altered circuit connectivity for social rescue of the Cntnap2 knockout mouse. Neuron. 2022;110:795–808e6.

Article  CAS  PubMed  Google Scholar 

Pickles A et al. Parent-mediated social communication therapy for young children with autism (PACT): long-term follow-up of a randomised controlled trial. Lancet 388, 2501–9.

Estes A, et al. Long-term outcomes of early intervention in 6-Year-old children with Autism Spectrum Disorder. J Am Acad Child Adolesc Psychiatry. 2015;54:580–7.

Article  PubMed