Wang J, Sun M, Liu W, Li Y, Li M. Stem cell-based therapies for liver diseases: an overview and update. Tissue Eng Regen Med. 2019;16(2):107–18.
Article PubMed PubMed Central Google Scholar
Huang H, Guo S, Chen Y-Q, Liu Y-X, Jin J-Y, Liang Y, et al. Increased RTN3 phenocopies nonalcoholic fatty liver disease by inhibiting the AMPK-IDH2 pathway. MedCommun. 2023;4(2):e226.
Ling S, Jiang G, Que Q, Xu S, Chen J, Xu X. Liver transplantation in patients with liver failure: twenty years of experience from China. Liver Int. 2022;42(9):2110–6.
Dwyer BJ, Macmillan MT, Brennan PN, Forbes SJ. Cell therapy for advanced liver diseases: repair or rebuild. J Hepatol. 2021;74(1):185–99.
Article CAS PubMed Google Scholar
Wahid NA, Rosenblatt R, Brown RS. A review of the current state of liver transplantation disparities. Liver Transpl. 2021;27(3):434–43.
Zhou J, Chen J, Wei Q, Saeb-Parsy K, Xu X. The role of ischemia/reperfusion injury in early hepatic allograft dysfunction. Liver Transpl. 2020;26(8):1034–48.
Wang Z, Gao W, Dong C, Sun C, Wang K, Zhang W, et al. Outcome of split-liver transplantation from pediatric donors weighing 25 kg or less. Liver Transpl. 2022;5:417.
Zheng S-S, Yang Z, Wu Y-C. Liver transplantation for intrahepatic and perihilar cholangiocarcinoma: current and future. Hepatobiliary Pancreat Dis Int. 2020;19(2):101–2.
Okano H, Sipp D. New trends in cellular therapy. Development. 2020;147(18):471.
Zheng X, Zhou X, Ma G, Yu J, Zhang M, Yang C, et al. Endogenous Follistatin-like 1 guarantees the immunomodulatory properties of mesenchymal stem cells during liver fibrotic therapy. Stem Cell Res Ther. 2022;13(1):403.
Article CAS PubMed PubMed Central Google Scholar
Margiana R, Markov A, Zekiy AO, Hamza MU, Al-Dabbagh KA, Al-Zubaidi SH, et al. Clinical application of mesenchymal stem cell in regenerative medicine: a narrative review. Stem Cell Res Ther. 2022;13(1):366.
Article CAS PubMed PubMed Central Google Scholar
Bram Y, Nguyen D-HT, Gupta V, Park J, Richardson C, Chandar V, et al. Cell and tissue therapy for the treatment of chronic liver disease. Annu Rev Biomed Eng. 2021;23:517–46.
Article CAS PubMed PubMed Central Google Scholar
Tatsumi K, Okano T. Hepatocyte transplantation: cell sheet technology for liver cell transplantation. Curr Transpl Rep. 2017;4(3):184–92.
Li T-T, Wang Z-R, Yao W-Q, Linghu E-Q, Wang F-S, Shi L. Stem cell therapies for chronic liver diseases: progress and challenges. Stem Cells Transl Med. 2022;11(9):900–11.
Article PubMed PubMed Central Google Scholar
Strom SC, Bruzzone P, Cai H, Ellis E, Lehmann T, Mitamura K, et al. Hepatocyte transplantation: clinical experience and potential for future use. Cell Transpl. 2006;15(Suppl 1):S105–10.
Hansel MC, Gramignoli R, Skvorak KJ, Dorko K, Marongiu F, Blake W, et al. The history and use of human hepatocytes for the treatment of liver diseases: the first 100 patients. Curr Protoc Toxicol. 2014;62:14–1223.
Article PubMed Central Google Scholar
Forbes SJ, Gupta S, Dhawan A. Cell therapy for liver disease: from liver transplantation to cell factory. J Hepatol. 2015;62(1 Suppl):S157–69.
Article CAS PubMed Google Scholar
Shafritz DA, Oertel M. Model systems and experimental conditions that lead to effective repopulation of the liver by transplanted cells. Int J Biochem Cell Biol. 2011;43(2):198–213.
Article CAS PubMed Google Scholar
Karnezis AN, Dorokhov M, Grompe M, Zhu L. Loss of p27(Kip1) enhances the transplantation efficiency of hepatocytes transferred into diseased livers. J Clin Invest. 2001;108(3):383–90.
Article CAS PubMed PubMed Central Google Scholar
Pu W, Zhou B. Hepatocyte generation in liver homeostasis, repair, and regeneration. Cell Regen. 2022;11(1):2.
Article CAS PubMed PubMed Central Google Scholar
Deng X, Zhang X, Li W, Feng R-X, Li L, Yi G-R, et al. Chronic liver injury induces conversion of biliary epithelial cells into hepatocytes. Cell Stem Cell. 2018;23(1):4587.
Raven A, Lu W-Y, Man TY, Ferreira-Gonzalez S, O’Duibhir E, Dwyer BJ, et al. Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration. Nature. 2017;547(7663):350–4.
Article CAS PubMed PubMed Central Google Scholar
Sampaziotis F, Muraro D, Tysoe OC, Sawiak S, Beach TE, Godfrey EM, et al. Cholangiocyte organoids can repair bile ducts after transplantation in the human liver. Science. 2021;371(6531):839–46.
Article CAS PubMed PubMed Central Google Scholar
Hallett JM, Ferreira-Gonzalez S, Man TY, Kilpatrick AM, Esser H, Thirlwell K, et al. Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease. Cell Stem Cell. 2022;29(3):589.
Tsuchiya A, Takeuchi S, Watanabe T, Yoshida T, Nojiri S, Ogawa M, et al. Mesenchymal stem cell therapies for liver cirrhosis: MSCs as “conducting cells” for improvement of liver fibrosis and regeneration. Inflamm Regen. 2019;39:18.
Article PubMed PubMed Central Google Scholar
Alfaifi M, Eom YW, Newsome PN, Baik SK. Mesenchymal stromal cell therapy for liver diseases. J Hepatol. 2018;68(6):1272–85.
Article CAS PubMed Google Scholar
Wang X, Willenbring H, Akkari Y, Torimaru Y, Foster M, Al-Dhalimy M, et al. Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature. 2003;422(6934):897–901.
Article CAS PubMed Google Scholar
Vassilopoulos G, Wang P-R, Russell DW. Transplanted bone marrow regenerates liver by cell fusion. Nature. 2003;422(6934):901–4.
Article CAS PubMed Google Scholar
Li W, Li L, Hui L. Cell plasticity in liver regeneration. Trends Cell Biol. 2020;30(4):329–38.
Li B, Wang X, Wang Y, Gou W, Yuan X, Peng J, et al. Past, present, and future of microcarrier-based tissue engineering. J Orthop Translat. 2015;3(2):51–7.
Article PubMed PubMed Central Google Scholar
Dhawan A, Chaijitraruch N, Fitzpatrick E, Bansal S, Filippi C, Lehec SC, et al. Alginate microencapsulated human hepatocytes for the treatment of acute liver failure in children. J Hepatol. 2020;72(5):877–84.
Article CAS PubMed Google Scholar
Merrell AJ, Peng T, Li J, Sun K, Li B, Katsuda T, et al. Dynamic transcriptional and epigenetic changes drive cellular plasticity in the liver. Hepatology. 2021;74(1):444–57.
Article CAS PubMed Google Scholar
Ding J, Yannam GR, Roy-Chowdhury N, Hidvegi T, Basma H, Rennard SI, et al. Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytes. J Clin Invest. 2011;121(5):1930–4.
Article CAS PubMed PubMed Central Google Scholar
Liu Y, Maya S, Ploss A. Animal models of hepatitis B virus infection-success, challenges, and future directions. Viruses. 2021;13(5):4589.
Azuma H, Paulk N, Ranade A, Dorrell C, Al-Dhalimy M, Ellis E, et al. Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice. Nat Biotechnol. 2007;25(8):903–10.
Article CAS PubMed PubMed Central Google Scholar
Fox IJ, Chowdhury JR, Kaufman SS, Goertzen TC, Chowdhury NR, Warkentin PI, et al. Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation. N Engl J Med. 1998;338(20):1422–6.
Article CAS PubMed Google Scholar
Dhawan A, Puppi J, Hughes RD, Mitry RR. Human hepatocyte transplantation: current experience and future challenges. Nat Rev Gastroenterol Hepatol. 2010;7(5):288–98.
Soltys KA, Soto-Gutiérrez A, Nagaya M, Baskin KM, Deutsch M, Ito R, et al. Barriers to the successful treatment of liver disease by hepatocyte transplantation. J Hepatol. 2010;53(4):769–74.
Article PubMed PubMed Central Google Scholar
Enosawa S, Horikawa R, Yamamoto A, Sakamoto
留言 (0)